AutismKB 2.0

Annotation Detail for GNA12


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Basic Information Top
Gene Symbol:GNA12 ( MGC104623,MGC99644,NNX3,RMP,gep )
Gene Full Name: guanine nucleotide binding protein (G protein) alpha 12
Band: 7p22.3-p22.2
Quick LinksEntrez ID:2768; OMIM: 604394; Uniprot ID:GNA12_HUMAN; ENSEMBL ID: ENSG00000146535; HGNC ID: 4380
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
40Phosphoserine (By similarity).
Location(AA) Modifications Resource
11S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
208Phosphothreonine(PKC)HMM predict
233Phosphoserine(ATM)HMM predict
257Phosphotyrosine(Jak)HMM predict
257Phosphotyrosine(Syk)HMM predict
307Phosphothreonine(PKC)HMM predict
341N-linkedHMM predict
351Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007353
  • Location:chr7 2734268-2850484
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
AR prostate-cancerGSE14092 2866646 2867400 754 16539
CBP T30-glioblastomaGSE21026 2868520 2871479 2959 19515
CTCF G2GSE9613 2863812 2863994 182 13419
CTCF G2GSE9613 2869393 2869894 501 19159
FOXA1 MCF7GSE15244 2863582 2863994 412 13304
Fos K562GSE19551 2850228 2851299 1071 279
Fos K562GSE19551 2869669 2870220 551 19460
FoxA1 MCF7MACSdata 2863546 2863847 301 13212
P300 T0-glioblastomaGSE21026 2869316 2870448 1132 19398
P300 T30-glioblastomaGSE21026 2868785 2870896 2111 19356
PHF8 293TGSE20725 2850682 2851419 737 566
Rb QuiescentGSE19898 2850527 2850712 185 135
TAF HelaGSE8489 2855811 2856081 270 5462
p130 QuiescentGSE19898 2869495 2870277 782 19402
p130 SenescentGSE19898 2869673 2869998 325 19351
p130 shRbQuiescentGSE19898 2869563 2870327 764 19461
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2730485 2730808 323 3622
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 2740465 2742117 1652 0
CBP T30-glioblastomaGSE21026 2763283 2765092 1809 0
CTCF G2GSE9613 2740258 2740549 291 0
CTCF G2GSE9613 2741300 2741683 383 0
CTCF G2GSE9613 2742686 2743116 430 0
CTCF G2GSE9613 2766271 2767607 1336 0
CTCF G2GSE9613 2768714 2769170 456 0
CTCF G2GSE9613 2781557 2781916 359 0
CTCF G2GSE9613 2793068 2793209 141 0
CTCF G2GSE9613 2795803 2796097 294 0
CTCF G2GSE9613 2815223 2815357 134 0
CTCF G2GSE9613 2821064 2821398 334 0
CTCF G2GSE9613 2849892 2850440 548 0
ER MCF7GSE19013 2816926 2817744 818 0
FOXA1 MCF7GSE15244 2808566 2809884 1318 0
FOXA1 MCF7GSE15244 2836864 2837487 623 0
Fos K562GSE19551 2763680 2764894 1214 0
H3ac HepG2E 2808566 2810604 2038 0
KLF4 hESGSE17917 2839288 2839463 175 0
NFkBII GM10847GSE19485 2778669 2779776 1107 0
NFkBII GM12878GSE19485 2826969 2829009 2040 0
P300 T30-glioblastomaGSE21026 2763219 2765156 1937 0
PHF8 HeLaGSE20725 2849882 2850847 965 0
PHF8 Hs68plusFBSGSE20725 2849740 2850683 943 0
RARA MCF7GSE15244 2763872 2764290 418 0
RARA MCF7GSE15244 2808670 2809919 1249 0
Rb SenescentGSE19898 2802557 2802755 198 0
Rb SenescentGSE19898 2828039 2828293 254 0
TFAP2C MCF7GSE21234 2763500 2764853 1353 0
TFAP2C MCF7GSE21234 2816902 2817723 821 0
TFAP2C MCF7GSE21234 2835170 2835630 460 0
TFAP2C MCF7GSE21234 2840827 2841706 879 0
hScc1 BcellGSE12603 2849967 2850670 703 0
hScc1 CdLSGSE12603 2849826 2850440 614 0
hScc1 G2GSE9613 2849892 2850633 741 0
p130 SenescentGSE19898 2764469 2764947 478 0
p130 shRbQuiescentGSE19898 2802537 2802899 362 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018