AutismKB 2.0

Annotation Detail for GNAI1


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Basic Information Top
Gene Symbol:GNAI1 ( Gi )
Gene Full Name: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Band: 7q21.11
Quick LinksEntrez ID:2770; OMIM: 139310; Uniprot ID:GNAI1_HUMAN; ENSEMBL ID: ENSG00000127955; HGNC ID: 4384
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
178ADP-ribosylarginine; by cholera toxin (By
351ADP-ribosylcysteine; by pertussis toxin
Location(AA) Modifications Resource
2N-myristoyl glycine (By similarity).Swiss-Prot 53.0
3S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
178ADP-ribosylarginine; by cholera toxin (Bysimilarity).Swiss-Prot 53.0
351ADP-ribosylcysteine; by pertussis toxin(By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
61Phosphotyrosine(EGFR)HMM predict
149N-linkedHMM predict
167SulfotyrosineHMM predict
252Phosphoserine(IKK)HMM predict
281Phosphoserine(CDC2)HMM predict
296Phosphotyrosine(INSR)HMM predict
296Phosphotyrosine(SRC)HMM predict
296Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002069
  • Location:chr7 79602075-79686656
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog ESGSE20650 79595019 79595527 508 6803
Nanog hESGSE18292 79594954 79595514 560 6842
Oct1 H2O2-HelaGSE14283 79593989 79594026 37 8068
Oct1 HelaGSE14283 79589756 79589833 77 12281
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 79698235 79698280 45 11601
ER E2-MCF7GSE14664 79699922 79699959 37 13284
Oct1 HelaGSE14283 79698237 79698283 46 11604
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 79601667 79602878 1211 0
ER E2-MCF7GSE14664 79684789 79684834 45 0
ER Fulvestrant-MCF7GSE14664 79603428 79603471 43 0
ER Fulvestrant-MCF7GSE14664 79674687 79674725 38 0
GABP k562GSE8489 79616241 79616379 138 0
Nanog ESGSE20650 79632477 79632806 329 0
Oct1 H2O2-HelaGSE14283 79606805 79606836 31 0
Oct1 H2O2-HelaGSE14283 79617522 79617554 32 0
Oct1 H2O2-HelaGSE14283 79623750 79623782 32 0
Oct1 HelaGSE14283 79606805 79606834 29 0
Oct1 HelaGSE14283 79617522 79617554 32 0
Oct1 HelaGSE14283 79623752 79623782 30 0
Oct1 HelaGSE14283 79630380 79630428 48 0
Oct1 HelaGSE14283 79673208 79673240 32 0
Oct1 HelaGSE14283 79674685 79674724 39 0
PAX3-FKHR Rh4GSE19063 79677260 79678366 1106 0
PHF8 293TGSE20725 79601677 79602517 840 0
PHF8 HeLaGSE20725 79601428 79602961 1533 0
RNAII Tamoxifen-MCF7GSE14664 79671477 79671575 98 0
USF1 HepG2E 79677343 79678188 845 0
hScc1 BcellGSE12603 79602503 79602937 434 0
hScc1 G2GSE9613 79601576 79603259 1683 0
p63 keratinocytesGSE17611 79618008 79619030 1022 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018