AutismKB 2.0

Annotation Detail for GNAS


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Basic Information Top
Gene Symbol:GNAS ( AHO,C20orf45,GNAS1,GPSA,GSA,GSP,MGC33735,NESP,PHP1A,PHP1B,PHP1C,POH )
Gene Full Name: GNAS complex locus
Band: 20q13.32
Quick LinksEntrez ID:2778; OMIM: 139320; Uniprot ID:ALEX_HUMAN; ENSEMBL ID: ENSG00000087460,ENSG00000213705; HGNC ID: 4392
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
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Location(AA) Modification Resource
11N-linkedHMM predict
40Phosphothreonine(PKA)HMM predict
61Phosphoserine(CDC2)HMM predict
61Phosphoserine(IKK)HMM predict
76Phosphoserine(IKK)HMM predict
78Phosphoserine(MAPK)HMM predict
79Phosphoserine(CK2)HMM predict
84Phosphoserine(CK1)HMM predict
93O-linkedHMM predict
95O-linkedHMM predict
95Phosphoserine(ATM)HMM predict
103Phosphoserine(MAPK)HMM predict
109Phosphotyrosine(EGFR)HMM predict
109Phosphotyrosine(INSR)HMM predict
109Phosphotyrosine(Syk)HMM predict
109SulfotyrosineHMM predict
134O-linkedHMM predict
135Phosphothreonine(CDK)HMM predict
139Phosphoserine(CDC2)HMM predict
139Phosphoserine(CDK)HMM predict
139Phosphoserine(ATM)HMM predict
147Phosphotyrosine(Syk)HMM predict
154Phosphotyrosine(INSR)HMM predict
154Phosphotyrosine(Jak)HMM predict
155O-linkedHMM predict
169Phosphotyrosine(INSR)HMM predict
169Phosphotyrosine(SRC)HMM predict
170Phosphoserine(CDK)HMM predict
174Phosphoserine(CDC2)HMM predict
174Phosphoserine(CDK)HMM predict
174PhosphoserineHMM predict
176O-linkedHMM predict
181O-linkedHMM predict
181O-linkedHMM predict
182O-linkedHMM predict
182O-linkedHMM predict
187Phosphoserine(ATM)HMM predict
188Phosphothreonine(PKA)HMM predict
190Phosphotyrosine(Jak)HMM predict
204Phosphoserine(PKA)HMM predict
213MethylarginineHMM predict
215O-linkedHMM predict
215Phosphoserine(ATM)HMM predict
216Phosphotyrosine(INSR)HMM predict
216Phosphotyrosine(Jak)HMM predict
217O-linkedHMM predict
219O-linkedHMM predict
225Phosphothreonine(PKC)HMM predict
230O-linkedHMM predict
230Phosphoserine(CAMK2)HMM predict
230Phosphoserine(IKK)HMM predict
233Phosphoserine(CDC2)HMM predict
233Phosphoserine(CDK)HMM predict
235Phosphoserine(CK1)HMM predict
237Phosphoserine(ATM)HMM predict
256O-linkedHMM predict
256O-linkedHMM predict
261N-linkedHMM predict
261O-linkedHMM predict
262O-linkedHMM predict
264N-linkedHMM predict
267O-linkedHMM predict
271O-linkedHMM predict
275Phosphoserine(PKG)HMM predict
277Phosphoserine(CDC2)HMM predict
277Phosphoserine(CDK)HMM predict
294N-linkedHMM predict
316Phosphothreonine(PKA)HMM predict
318Phosphotyrosine(INSR)HMM predict
321Phosphothreonine(CDC2)HMM predict
325O-linkedHMM predict
325Phosphothreonine(CDC2)HMM predict
325Phosphothreonine(MAPK)HMM predict
335Phosphothreonine(PKC)HMM predict
350O-linkedHMM predict
359Phosphothreonine(MAPK)HMM predict
363Phosphoserine(ATM)HMM predict
378Phosphotyrosine(INSR)HMM predict
378Phosphotyrosine(Abl)HMM predict
380O-linkedHMM predict
380Phosphothreonine(CDK)HMM predict
380Phosphoserine(CDC2)HMM predict
386Phosphothreonine(MAPK)HMM predict
392Phosphothreonine(CDK)HMM predict
398Phosphothreonine(MAPK)HMM predict
404Phosphoserine(IKK)HMM predict
407Phosphothreonine(CDC2)HMM predict
413Phosphoserine(IKK)HMM predict
431Phosphoserine(IKK)HMM predict
443O-linkedHMM predict
443Phosphoserine(IKK)HMM predict
455O-linkedHMM predict
455Phosphoserine(IKK)HMM predict
464Phosphoserine(IKK)HMM predict
466Phosphoserine(ATM)HMM predict
492Phosphoserine(CDC2)HMM predict
503O-linkedHMM predict
503O-linkedHMM predict
513Phosphothreonine(MAPK)HMM predict
513Phosphothreonine(CDK)HMM predict
515Phosphoserine(PKG)HMM predict
515Phosphoserine(PKB)HMM predict
518O-linkedHMM predict
520O-linkedHMM predict
520O-linkedHMM predict
532Phosphoserine(CDC2)HMM predict
532Phosphoserine(MAPK)HMM predict
540Phosphoserine(IKK)HMM predict
542O-linkedHMM predict
542O-linkedHMM predict
542O-linkedHMM predict
542Phosphothreonine(MAPK)HMM predict
544O-linkedHMM predict
546O-linkedHMM predict
548O-linkedHMM predict
550O-linkedHMM predict
564Phosphotyrosine(Syk)HMM predict
565Phosphoserine(CDC2)HMM predict
571Phosphoserine(CK2)HMM predict
572Phosphoserine(CK2)HMM predict
572Phosphoserine(ATM)HMM predict
576Phosphoserine(CK1)HMM predict
576Phosphoserine(CK2)HMM predict
577Phosphoserine(CK1)HMM predict
577Phosphoserine(CK2)HMM predict
609N-linkedHMM predict
610N-linkedHMM predict
613Phosphothreonine(PKC)HMM predict
622ThreonineHMM predict
625CysteineHMM predict
625Phosphoserine(CDC2)HMM predict
625Phosphoserine(CDK)HMM predict
625Phosphoserine(ATM)HMM predict
680Phosphotyrosine(INSR)HMM predict
790Phosphotyrosine(Syk)HMM predict
812Phosphotyrosine(INSR)HMM predict
812Phosphotyrosine(SRC)HMM predict
833Phosphotyrosine(Jak)HMM predict
904N-linkedHMM predict
907N-linkedHMM predict
961Phosphotyrosine(INSR)HMM predict
968O-linkedHMM predict
968Phosphothreonine(CDC2)HMM predict
968Phosphothreonine(MAPK)HMM predict
978Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001077488
  • Location:chr20 56900163-56919643
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 56916196 56916774 578 0
hScc1 BcellGSE12603 56901069 56901450 381 0
hScc1 BcellGSE12603 56912044 56912276 232 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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