AutismKB 2.0

Annotation Detail for GOT2


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Basic Information Top
Gene Symbol:GOT2 ( FLJ40994,KAT4,KATIV,mitAAT )
Gene Full Name: glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
Band: 16q21
Quick LinksEntrez ID:2806; OMIM: 138150; Uniprot ID:AATM_HUMAN; ENSEMBL ID: ENSG00000125166; HGNC ID: 4433
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
73N6-acetyllysine.
90N6-acetyllysine.
94N6-acetyllysine (By similarity).
96Phosphotyrosine.
150N6-acetyllysine.
159N6-acetyllysine.
185N6-acetyllysine (By similarity).
234N6-acetyllysine.
279N6-(pyridoxal phosphate)lysine (By
296N6-acetyllysine.
345N6-acetyllysine (By similarity).
363N6-acetyllysine (By similarity).
396N6-acetyllysine.
401Phosphotyrosine.
404N6-acetyllysine.
Location(AA) Modifications Resource
94N6-acetyllysine (By similarity).Swiss-Prot 53.0
159N6-acetyllysine (By similarity).Swiss-Prot 53.0
185N6-acetyllysine (By similarity).Swiss-Prot 53.0
296N6-acetyllysine (By similarity).Swiss-Prot 53.0
345N6-acetyllysine (By similarity).Swiss-Prot 53.0
363N6-acetyllysine (By similarity).Swiss-Prot 53.0
401Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
26O-linkedHMM predict
55Phosphothreonine(PKA)HMM predict
75Phosphotyrosine(INSR)HMM predict
96Phosphotyrosine(Syk)HMM predict
164N-linkedHMM predict
215N-linkedHMM predict
231Phosphothreonine(PKC)HMM predict
401Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002080
  • Location:chr16 57298535-57325746
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 57325651 57325930 279 44
CTCF CD4SISSRdata 57325651 57325930 279 44
CTCF JurkatGSE12889 57325671 57325901 230 40
Oct1 H2O2-HelaGSE14283 57342418 57342448 30 16687
Oct1 HelaGSE14283 57342388 57342449 61 16672
Oct4 hESGSE17917 57325707 57325936 229 75
p130 SenescentGSE19898 57325823 57326043 220 187
p63 keratinocytesGSE17611 57334549 57335221 672 9139
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 57324960 57325995 1035 0
FOXA1 MCF7GSE15244 57312290 57312799 509 0
H3K4me3 colorectalcancer 57324216 57325202 986 0
H3ac HepG2E 57323893 57324768 875 0
Oct1 H2O2-HelaGSE14283 57312849 57312900 51 0
Oct1 H2O2-HelaGSE14283 57312920 57312946 26 0
Oct1 HelaGSE14283 57312669 57313037 368 0
Oct1 HelaGSE14283 57325563 57325594 31 0
PHF8 293TGSE20725 57324903 57326176 1273 0
PHF8 HeLaGSE20725 57324832 57325975 1143 0
PHF8 Hs68plusFBSGSE20725 57324816 57326219 1403 0
Rb GrowingGSE19898 57325011 57325130 119 0
Rb QuiescentGSE19898 57324911 57325156 245 0
hScc1 BcellGSE12603 57324921 57325305 384 0
hScc1 CdLSGSE12603 57324960 57325234 274 0
p130 SenescentGSE19898 57324919 57325130 211 0
p130 SenescentGSE19898 57325352 57325798 446 0
p130 shRbSenescentGSE19898 57325208 57325610 402 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018