AutismKB 2.0

Annotation Detail for SFN


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Basic Information Top
Gene Symbol:SFN ( YWHAS )
Gene Full Name: stratifin
Band: 1p36.11
Quick LinksEntrez ID:2810; OMIM: 601290; Uniprot ID:1433S_HUMAN; ENSEMBL ID: ENSG00000175793; HGNC ID: 10773
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
64Phosphoserine (By similarity).
216Phosphoserine (By similarity).
248Phosphoserine.
Location(AA) Modifications Resource
64Phosphoserine (By similarity).Swiss-Prot 53.0
186Phosphoserine (MAPK8)Phospho.ELM 6.0
216Phosphoserine (By similarity).Swiss-Prot 53.0
248Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
19Phosphotyrosine(Syk)HMM predict
19SulfotyrosineHMM predict
74Phosphoserine(CK1)HMM predict
136Phosphothreonine(CK2)HMM predict
175N-linkedHMM predict
186Phosphoserine(CDC2)HMM predict
213Phosphotyrosine(Syk)HMM predict
226N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006142
  • Location:chr1 27062219-27063533
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27060348 27062954 2606 569
H3ac HepG2E 27060998 27061810 812 816
RARA MCF7GSE15244 27060249 27060968 719 1611
TAF HelaGSE8489 27060687 27061840 1153 956
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27063340 27064520 1180 397
Fos K562GSE19551 27063834 27064803 969 785
H3ac HepG2E 27066671 27067299 628 3452
LIN9 G0GSE7516 27063986 27064520 534 720
PHF8 293TGSE20725 27063679 27064966 1287 789
PHF8 Hs68minusFBSGSE20725 27063602 27064315 713 425
PHF8 Hs68minusFBSGSE20725 27064443 27064953 510 1165
Pol2 GM12878GSE19551 27063662 27065254 1592 925
Rb GrowingGSE19898 27063841 27064422 581 598
Rb QuiescentGSE19898 27064079 27064659 580 836
Rb SenescentGSE19898 27063944 27064700 756 789
TAF HelaGSE8489 27063366 27064189 823 244
hScc1 BcellGSE12603 27063949 27064520 571 701
p130 SenescentGSE19898 27063846 27064447 601 613
p130 SenescentGSE19898 27064564 27064827 263 1162
p130 shRbQuiescentGSE19898 27063867 27064785 918 793
p130 shRbSenescentGSE19898 27063800 27064787 987 760
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 27062341 27064225 1884 0
p130 shRbSenescentGSE19898 27062663 27062806 143 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018