AutismKB 2.0

Annotation Detail for GPD2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GPD2 ( GDH2,GPDM,mGPDH )
Gene Full Name: glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
Band: 2q24.1
Quick LinksEntrez ID:2820; OMIM: 138430; Uniprot ID:GPDM_HUMAN; ENSEMBL ID: ENSG00000115159; HGNC ID: 4456
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
600Phosphotyrosine (By similarity).
601Phosphotyrosine (By similarity).
634N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
25Phosphoserine(ATM)HMM predict
47Phosphoserine(CK1)HMM predict
66N-linkedHMM predict
82Phosphoserine(IKK)HMM predict
288N-linkedHMM predict
357Phosphothreonine(MAPK)HMM predict
415Phosphoserine(IKK)HMM predict
439Phosphothreonine(PKC)HMM predict
605Phosphotyrosine(Syk)HMM predict
628Phosphotyrosine(Jak)HMM predict
697Phosphoserine(PKG)HMM predict
720ValineHMM predict
725GlycineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000408
  • Location:chr2 157001165-157148161
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 157000582 157001202 620 274
ER E2-MCF7GSE14664 156985612 156985644 32 15538
FOXA1 MCF7GSE15244 156995222 156996087 865 5511
Myc hESGSE17917 157000699 157001085 386 274
PHF8 HeLaGSE20725 157000072 157001600 1528 330
PHF8 Hs68minusFBSGSE20725 157000088 157001473 1385 385
PHF8 Hs68plusFBSGSE20725 157000109 157001464 1355 379
RARA MCF7GSE15244 156995222 156996044 822 5533
Rb QuiescentGSE19898 157001021 157001258 237 26
Rb shRbSenescenceGSE19898 157001021 157001219 198 46
hScc1 BcellGSE12603 157000746 157001165 419 210
p130 QuiescentGSE19898 157000570 157001595 1025 83
p130 SenescentGSE19898 157000610 157001699 1089 11
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 157159226 157159303 77 11103
hScc1 BcellGSE12603 157154332 157154884 552 6447
hScc1 CdLSGSE12603 157154141 157155025 884 6422
hScc1 G2GSE9613 157154254 157155095 841 6513
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 157001123 157001695 572 0
ER E2-MCF7GSE14664 157001668 157001745 77 0
ER E2-MCF7GSE14664 157006244 157006286 42 0
ER E2-MCF7GSE14664 157122029 157122064 35 0
ER E2-MCF7GSE14664 157138449 157138483 34 0
ER Fulvestrant-MCF7GSE14664 157029976 157030017 41 0
ER MCF7GSE19013 157101769 157102302 533 0
FOXA1 MCF7GSE15244 157020163 157021054 891 0
GABP k562GSE8489 157017795 157018347 552 0
H3K4me3 colorectalcancer 157001268 157002162 894 0
LIN9 G0GSE7516 157001165 157002057 892 0
Oct1 HelaGSE14283 157029925 157030013 88 0
Oct1 HelaGSE14283 157040159 157040186 27 0
Oct1 HelaGSE14283 157090742 157090771 29 0
Oct1 HelaGSE14283 157122029 157122067 38 0
Oct1 HelaGSE14283 157128889 157128966 77 0
Oct1 HelaGSE14283 157134125 157134155 30 0
Oct1 HelaGSE14283 157138446 157138483 37 0
Rb GrowingGSE19898 157001317 157001707 390 0
Rb QuiescentGSE19898 157001291 157001606 315 0
Rb SenescentGSE19898 157000788 157001639 851 0
Rb shRbQuiescentGSE19898 157011169 157011316 147 0
STAT1 HeLaGSE12783 157101379 157102616 1237 0
TAF HelaGSE8489 157001245 157002230 985 0
TAF k562GSE8489 157001331 157002230 899 0
TAF k562GSE8489 157017547 157018347 800 0
TAF k562GSE8489 157073791 157074030 239 0
TFAP2C MCF7GSE21234 157031825 157032261 436 0
p130 QuiescentGSE19898 157001615 157001853 238 0
p130 shRbQuiescentGSE19898 157001193 157001609 416 0
p130 shRbSenescentGSE19898 157000480 157001857 1377 0
p63 keratinocytesGSE17611 157002037 157003280 1243 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1161 Unknown pSILAC miR-1 GPD2 down 75-50% 18668040
1234 Unknown pSILAC miR-30 GPD2 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000115159 n_a n_a n_a "lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, sarcoma"
ENSG00000115159 n_a n_a n_a "lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved