AutismKB 2.0

Annotation Detail for MKX


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Basic Information Top
Gene Symbol:MKX ( C10orf48,IFRX,IRXL1,MGC39616 )
Gene Full Name: mohawk homeobox
Band: 10p12.1
Quick LinksEntrez ID:283078; OMIM: 601332; Uniprot ID:MKX_HUMAN; ENSEMBL ID: ENSG00000150051; HGNC ID: 23729
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
62Phosphothreonine(PKA)HMM predict
99Phosphothreonine(PKC)HMM predict
158Phosphoserine(CK2)HMM predict
158Phosphoserine(CK1)HMM predict
164Phosphoserine(IKK)HMM predict
164Phosphoserine(CK2)HMM predict
166Phosphoserine(CK2)HMM predict
182Phosphotyrosine(EGFR)HMM predict
182Phosphotyrosine(INSR)HMM predict
182Phosphotyrosine(Abl)HMM predict
212Phosphotyrosine(Jak)HMM predict
212Phosphotyrosine(Syk)HMM predict
228N-linkedHMM predict
238N-linkedHMM predict
249N-linkedHMM predict
265Phosphoserine(IKK)HMM predict
265Phosphoserine(MAPK)HMM predict
265Phosphoserine(CDC2)HMM predict
268Phosphoserine(CK2)HMM predict
269Phosphoserine(CK1)HMM predict
284N-linkedHMM predict
287N-linkedHMM predict
304Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_173576
  • Location:chr10 28001811-28074752
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 28075437 28076493 1056 1213
Rb GrowingGSE19898 28092194 28092391 197 17540
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 27989707 27989736 29 12090
TFAP2C MCF7GSE21234 27985624 27985907 283 16046
hScc1 CdLSGSE12603 27985849 27986028 179 15873
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 28071100 28071368 268 0
CTCF CD4SISSRdata 28071100 28071368 268 0
FoxA1 MCF7MACSdata 28067475 28067805 330 0
H3K27me3 colorectalcancer 28072678 28073193 515 0
H3K27me3 colorectalcancer 28073722 28074125 403 0
TFAP2C MCF7GSE21234 28070759 28071445 686 0
TFAP2C MCF7GSE21234 28073665 28074312 647 0
hScc1 BcellGSE12603 28070932 28071530 598 0
hScc1 BcellGSE12603 28073404 28073826 422 0
hScc1 CdLSGSE12603 28070861 28071530 669 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018