Annotation Detail for ZDHHC22

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Basic Information Top

Gene Symbol:	ZDHHC22 ( C14orf59 )
Gene Full Name:	zinc finger, DHHC-type containing 22
Band:	14q24.3
Quick Links	Entrez ID:283576; OMIM: NA; Uniprot ID:ZDH22_HUMAN; ENSEMBL ID: ENSG00000177108; HGNC ID: 20106
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:5 results

No data

Location(AA)	Modification	Resource
87	O-linked	HMM predict
87	Phosphothreonine(MAPK)	HMM predict
104	Phosphothreonine(PKA)	HMM predict
133	O-linked	HMM predict
247	Leucine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_174976
Location:chr14 76667373-76677886
strand:-

Upstream the gene:13 results
Downstream the gene:5 results
Inside the gene:17 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	76687537	76688327	790	10046
ER	MCF7	GSE19013	76680529	76681454	925	3105
Fos	K562	GSE19551	76684685	76685069	384	6991
H3K27me3	colorectal	cancer	76678732	76680310	1578	1635
H3K27me3	colorectal	cancer	76681583	76682756	1173	4283
Oct1	H2O2-Hela	GSE14283	76678117	76678144	27	244
P300	T30-glioblastoma	GSE21026	76694238	76694820	582	16643
Rb	Growing	GSE19898	76694332	76694589	257	16574
TFAP2C	MCF7	GSE21234	76681660	76682369	709	4128
hScc1	Bcell	GSE12603	76687537	76687889	352	9827
hScc1	CdLS	GSE12603	76687537	76687848	311	9806
hScc1	CdLS	GSE12603	76688327	76688698	371	10626
p130	shRbQuiescent	GSE19898	76693915	76694856	941	16499

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	76661033	76661324	291	6195
CTCF	CD4	SISSRdata	76661033	76661324	291	6195
NRSF	mAb	Jurkat	76664158	76668567	4409	1011
hScc1	Bcell	GSE12603	76660511	76661454	943	6391
hScc1	CdLS	GSE12603	76660760	76661350	590	6319

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	76675762	76675969	207	0
CTCF	CD4	SISSRdata	76675762	76675969	207	0
CTCF	G2	GSE9613	76667969	76668488	519	0
CTCF	G2	GSE9613	76675477	76675988	511	0
CTCF	G2	GSE9613	76677210	76677682	472	0
NRSF	Jurkat	GSE13047	76669005	76671149	2144	0
NRSF	mAb	Jurkat	76668941	76672056	3115	0
NRSF	mAb	Jurkat	76672673	76673555	882	0
NRSF	mAb	Jurkat	76673948	76674345	397	0
NRSF	mAb	Jurkat	76674691	76675667	976	0
NRSF-mono	Jurkat	QuESTdata	76668967	76670821	1854	0
NRSF-poly	Jurkat	QuESTdata	76669011	76671149	2138	0
Oct1	H2O2-Hela	GSE14283	76674497	76674537	40	0
Oct1	Hela	GSE14283	76674498	76674537	39	0
hScc1	Bcell	GSE12603	76675477	76676178	701	0
hScc1	Bcell	GSE12603	76677065	76677426	361	0
hScc1	CdLS	GSE12603	76675604	76676063	459	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
8171	mRNA		chr14	76676778	76679092	189	mRNA	ZDHHC22	chr14	76667373	76677887	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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