AutismKB 2.0

Annotation Detail for TSEN54


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Basic Information Top
Gene Symbol:TSEN54 ( FLJ37147,PCH2A,PCH4,SEN54L,sen54 )
Gene Full Name: tRNA splicing endonuclease 54 homolog (S. cerevisiae)
Band: 17q25.1
Quick LinksEntrez ID:283989; OMIM: 608755; Uniprot ID:SEN54_HUMAN; ENSEMBL ID: ENSG00000182173; HGNC ID: 27561
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
225Phosphoserine.
230Phosphoserine.
235Phosphoserine.
249Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
30Phosphoserine(IKK)HMM predict
30Phosphoserine(ATM)HMM predict
93Phosphoserine(CDC2)HMM predict
166Phosphotyrosine(Jak)HMM predict
175Phosphoserine(IKK)HMM predict
178Phosphoserine(CDC2)HMM predict
203Phosphoserine(IKK)HMM predict
203Phosphoserine(PKG)HMM predict
203Phosphoserine(PKA)HMM predict
204Phosphoserine(PKA)HMM predict
205Phosphoserine(CK1)HMM predict
206Phosphoserine(ATM)HMM predict
206Phosphoserine(CDC2)HMM predict
225Phosphoserine(IKK)HMM predict
229O-linkedHMM predict
230O-linkedHMM predict
235Phosphoserine(ATM)HMM predict
267Phosphoserine(ATM)HMM predict
267Phosphoserine(CDC2)HMM predict
406Phosphothreonine(MAPK)HMM predict
406Phosphothreonine(CDK)HMM predict
416O-linkedHMM predict
416Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_207346
  • Location:chr17 71024203-71032414
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 71023104 71024707 1603 298
NRSF-mono JurkatQuESTdata 71022880 71024618 1738 455
NRSF-poly JurkatQuESTdata 71023104 71024760 1656 272
Rb QuiescentGSE19898 71023930 71024195 265 141
Rb shRbQuiescentGSE19898 71023578 71023889 311 470
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 71032558 71032828 270 279
CTCF CD4SISSRdata 71032558 71032828 270 279
CTCF HelaGSE12889 71032645 71032828 183 322
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 71029049 71029327 278 0
CTCF G2GSE9613 71029789 71030058 269 0
H3ac HepG2E 71024876 71026295 1419 0
NRSF mAbJurkat 71025392 71026236 844 0
RARG MCF7GSE15244 71024903 71026090 1187 0
hScc1 BcellGSE12603 71024243 71024669 426 0
hScc1 BcellGSE12603 71029406 71029951 545 0
hScc1 CdLSGSE12603 71024243 71024631 388 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
11654 mRNA TSEN54 chr17 71024234 71032410 273 EST chr17 71028823 71029551Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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