Annotation Detail for NEK8
Basic Information Top
| Gene Symbol: | NEK8 ( JCK,MGC138445,NEK12A,NPHP9 ) |
|---|---|
| Gene Full Name: | NIMA (never in mitosis gene a)- related kinase 8 |
| Band: | 17q11.1 |
| Quick Links | Entrez ID:284086; OMIM: 609799; Uniprot ID:NEK8_HUMAN; ENSEMBL ID: ENSG00000160602; HGNC ID: 13387 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 162 | Phosphothreonine; by autocatalysis (By | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 162 | Phosphothreonine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 41 | Phosphothreonine(PKC) | HMM predict |
| 98 | Phosphoserine(CK1) | HMM predict |
| 98 | Phosphoserine(PKG) | HMM predict |
| 169 | Phosphotyrosine(INSR) | HMM predict |
| 180 | Phosphotyrosine(Abl) | HMM predict |
| 280 | Phosphoserine(IKK) | HMM predict |
| 284 | Phosphoserine(IKK) | HMM predict |
| 288 | O-linked | HMM predict |
| 323 | Phosphothreonine(MAPK) | HMM predict |
| 323 | Phosphothreonine(CDK) | HMM predict |
| 432 | Phosphoserine(ATM) | HMM predict |
| 484 | Phosphoserine(IKK) | HMM predict |
| 577 | O-linked | HMM predict |
| 601 | Phosphoserine(PKG) | HMM predict |
| 635 | Phosphotyrosine(SRC) | HMM predict |
| 666 | Phosphotyrosine(Syk) | HMM predict |
| 669 | O-linked | HMM predict |
| 674 | S-palmitoyl | HMM predict |
| 676 | Glycine | HMM predict |
- RefSeq ID: NM_178170
- Location:chr17 24079958-24093908
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| H3K4me3 | colorectal | cancer | 24079071 | 24079393 | 322 | 727 |
| H3ac | HepG2 | E | 24079071 | 24079724 | 653 | 561 |
| NFkBII | GM12878 | GSE19485 | 24077728 | 24080795 | 3067 | 697 |
| NFkBII | GM15510 | GSE19485 | 24077152 | 24080643 | 3491 | 1061 |
| NFkBII | GM18526 | GSE19485 | 24077570 | 24080585 | 3015 | 881 |
| RARG | MCF7 | GSE15244 | 24079071 | 24079616 | 545 | 615 |
| Rb | shRbSenescence | GSE19898 | 24079175 | 24079392 | 217 | 675 |
| hScc1 | Bcell | GSE12603 | 24079071 | 24079548 | 477 | 649 |
| hScc1 | CdLS | GSE12603 | 24079071 | 24080268 | 1197 | 289 |
| p130 | Quiescent | GSE19898 | 24079694 | 24079898 | 204 | 163 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| TFAP2C | MCF7 | GSE21234 | 24094105 | 24094862 | 757 | 575 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 24079863 | 24080064 | 201 | 0 |
| Fos | K562 | GSE19551 | 24086250 | 24086936 | 686 | 0 |
| Gata1 | K562 | GSE18868 | 24085743 | 24086902 | 1159 | 0 |
| NFkBII | GM10847 | GSE19485 | 24088662 | 24090730 | 2068 | 0 |
| NFkBII | GM12878 | GSE19485 | 24088780 | 24090751 | 1971 | 0 |
| NFkBII | GM12892 | GSE19485 | 24088750 | 24090769 | 2019 | 0 |
| NFkBII | GM15510 | GSE19485 | 24088369 | 24090764 | 2395 | 0 |
| NFkBII | GM18526 | GSE19485 | 24088656 | 24090777 | 2121 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 24090920 | 24090951 | 31 | 0 |
| Rb | Growing | GSE19898 | 24080004 | 24080251 | 247 | 0 |
| Rb | shRbQuiescent | GSE19898 | 24091474 | 24091745 | 271 | 0 |
| TAF | Hela | GSE8489 | 24081006 | 24081221 | 215 | 0 |
| TFAP2C | MCF7 | GSE21234 | 24079882 | 24080576 | 694 | 0 |
| p130 | Quiescent | GSE19898 | 24079930 | 24080184 | 254 | 0 |
| p130 | Senescent | GSE19898 | 24079942 | 24080373 | 431 | 0 |
| p130 | Senescent | GSE19898 | 24086644 | 24086895 | 251 | 0 |
Validated miRNA targets