AutismKB 2.0

Annotation Detail for LAMA1


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Basic Information Top
Gene Symbol:LAMA1 ( LAMA )
Gene Full Name: laminin, alpha 1
Band: 18p11.31
Quick LinksEntrez ID:284217; OMIM: 150320; Uniprot ID:LAMA1_HUMAN; ENSEMBL ID: ENSG00000101680; HGNC ID: 6481
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
38N-linked (GlcNAc...) (Potential).
555N-linked (GlcNAc...) (Potential).
665N-linked (GlcNAc...) (Potential).
763N-linked (GlcNAc...) (Potential).
926N-linked (GlcNAc...) (Potential).
952N-linked (GlcNAc...) (Potential).
1045N-linked (GlcNAc...) (Potential).
1407N-linked (GlcNAc...) (Potential).
1579N-linked (GlcNAc...) (Potential).
1596N-linked (GlcNAc...) (Potential).
1678N-linked (GlcNAc...) (Potential).
1689N-linked (GlcNAc...) (Potential).
1698N-linked (GlcNAc...) (Potential).
1717N-linked (GlcNAc...) (Potential).
1804N-linked (GlcNAc...) (Potential).
1894N-linked (GlcNAc...) (Potential).
1898N-linked (GlcNAc...) (Potential).
1957N-linked (GlcNAc...) (Potential).
1974N-linked (GlcNAc...) (Potential).
1991N-linked (GlcNAc...) (Potential).
2038N-linked (GlcNAc...) (Potential).
2047N-linked (GlcNAc...) (Potential).
2094N-linked (GlcNAc...) (Potential).
2098N-linked (GlcNAc...) (Potential).
2243N-linked (GlcNAc...).
2244N-linked (GlcNAc...) (Potential).
2384N-linked (GlcNAc...) (Potential).
2408N-linked (GlcNAc...) (Potential).
2518N-linked (GlcNAc...) (Potential).
2536Cell attachment site.
2619N-linked (GlcNAc...) (Potential).
2729N-linked (GlcNAc...) (Potential).
2852N-linked (GlcNAc...) (Potential).
2915N-linked (GlcNAc...) (Potential).
2983N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
38N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
351PhosphothreoninePhospho.ELM 6.0
555N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
665N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
763N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
926N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
952N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1045N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1407N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1579N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1596N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1678N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1689N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1698N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1717N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1804N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1894N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1898N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1957N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1974N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1991N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2038N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2047N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2094N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2098N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2243N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2244N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2384N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2408N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2518N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2619N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2729N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2852N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2915N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2983N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
12S-palmitoylHMM predict
38N-linkedHMM predict
157Phosphoserine(IKK)HMM predict
164N-linkedHMM predict
254Phosphothreonine(PKC)HMM predict
304S-palmitoylHMM predict
305S-palmitoylHMM predict
319O-linkedHMM predict
337Phosphotyrosine(Syk)HMM predict
380Phosphotyrosine(Jak)HMM predict
381Phosphotyrosine(Jak)HMM predict
381Phosphotyrosine(Jak)HMM predict
416Phosphoserine(CK1)HMM predict
514Phosphoserine(CK1)HMM predict
555N-linkedHMM predict
556N-linkedHMM predict
631Phosphotyrosine(Syk)HMM predict
634Phosphotyrosine(Syk)HMM predict
665N-linkedHMM predict
742S-palmitoylHMM predict
763N-linkedHMM predict
801N-linkedHMM predict
838N-linkedHMM predict
849S-palmitoylHMM predict
926N-linkedHMM predict
952N-linkedHMM predict
990SulfotyrosineHMM predict
998S-palmitoylHMM predict
1045N-linkedHMM predict
1063S-palmitoylHMM predict
1150S-palmitoylHMM predict
1165Phosphotyrosine(EGFR)HMM predict
1183Phosphoserine(CAMK2)HMM predict
1195Phosphotyrosine(SRC)HMM predict
1312Phosphoserine(IKK)HMM predict
1407N-linkedHMM predict
1445Phosphoserine(IKK)HMM predict
1454S-palmitoylHMM predict
1457Phosphoserine(MAPK)HMM predict
1457Phosphoserine(IKK)HMM predict
1463O-linkedHMM predict
1493Phosphoserine(CK1)HMM predict
1496Phosphotyrosine(INSR)HMM predict
1496Phosphotyrosine(Syk)HMM predict
1501Phosphothreonine(MAPK)HMM predict
1509S-palmitoylHMM predict
1579N-linkedHMM predict
1596N-linkedHMM predict
1678N-linkedHMM predict
1689N-linkedHMM predict
1694N-linkedHMM predict
1698N-linkedHMM predict
1717N-linkedHMM predict
1730Phosphoserine(CK1)HMM predict
1755Phosphoserine(CK1)HMM predict
1804N-linkedHMM predict
1898N-linkedHMM predict
1931O-linkedHMM predict
1970Phosphoserine(CK1)HMM predict
1974N-linkedHMM predict
1977N-linkedHMM predict
2017O-linkedHMM predict
2017O-linkedHMM predict
2021O-linkedHMM predict
2021Phosphoserine(IKK)HMM predict
2025Phosphothreonine(PKC)HMM predict
2047N-linkedHMM predict
2098N-linkedHMM predict
2100Phosphoserine(CAMK2)HMM predict
2137O-linkedHMM predict
2226Phosphoserine(CDC2)HMM predict
2226Phosphoserine(CDK)HMM predict
2226Phosphoserine(IKK)HMM predict
2230O-linkedHMM predict
2230Phosphothreonine(PKC)HMM predict
2231O-linkedHMM predict
2233O-linkedHMM predict
2233Phosphoserine(CDC2)HMM predict
2244N-linkedHMM predict
2260Phosphoserine(CDC2)HMM predict
2300Phosphoserine(CDK)HMM predict
2301Phosphoserine(ATM)HMM predict
2315Phosphotyrosine(INSR)HMM predict
2337Phosphoserine(CDK)HMM predict
2350Phosphothreonine(PKC)HMM predict
2384N-linkedHMM predict
2408N-linkedHMM predict
2411N-linkedHMM predict
2419Phosphothreonine(MAPK)HMM predict
2505Phosphoserine(CK2)HMM predict
2505Phosphoserine(CDC2)HMM predict
2505Phosphoserine(MAPK)HMM predict
2518N-linkedHMM predict
2638Phosphothreonine(PKC)HMM predict
2843Phosphoserine(ATM)HMM predict
2852N-linkedHMM predict
2900Phosphotyrosine(INSR)HMM predict
2908Phosphotyrosine(Syk)HMM predict
2915N-linkedHMM predict
2924Phosphoserine(IKK)HMM predict
2983N-linkedHMM predict
2990Phosphothreonine(PKA)HMM predict
3008O-linkedHMM predict
3009Phosphoserine(IKK)HMM predict
3017Phosphotyrosine(INSR)HMM predict
3017SulfotyrosineHMM predict
3035Phosphoserine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005559
  • Location:chr18 6931887-7107812
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 7114692 7114730 38 6899
Oct1 H2O2-HelaGSE14283 7119269 7119298 29 11471
Oct1 HelaGSE14283 7114692 7114730 38 6899
Oct1 HelaGSE14283 7119267 7119305 38 11474
Rb GrowingGSE19898 7122976 7123122 146 15237
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 6926903 6926949 46 4962
hScc1 BcellGSE12603 6919420 6920131 711 12112
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 6935531 6935788 257 0
CTCF G2GSE9613 6942754 6943173 419 0
CTCF G2GSE9613 6944640 6944898 258 0
CTCF G2GSE9613 6988203 6988392 189 0
CTCF G2GSE9613 6990274 6990943 669 0
CTCF G2GSE9613 7010697 7010989 292 0
CTCF G2GSE9613 7012082 7012983 901 0
CTCF G2GSE9613 7028116 7028653 537 0
CTCF G2GSE9613 7107034 7108044 1010 0
ER E2-MCF7GSE14664 7042370 7042403 33 0
H3K27me3 colorectalcancer 7105375 7105632 257 0
H3K27me3 colorectalcancer 7105981 7106889 908 0
Myc K562GSE19551 7012213 7012714 501 0
Oct1 H2O2-HelaGSE14283 6983607 6983639 32 0
Oct1 H2O2-HelaGSE14283 6994397 6994429 32 0
Oct1 HelaGSE14283 6983606 6983639 33 0
Oct1 HelaGSE14283 6994395 6994437 42 0
Oct1 HelaGSE14283 7042371 7042399 28 0
Oct1 HelaGSE14283 7049995 7050041 46 0
Oct1 HelaGSE14283 7063975 7064007 32 0
Rb QuiescentGSE19898 7028634 7028986 352 0
Rb QuiescentGSE19898 7106798 7107067 269 0
Rb SenescentGSE19898 7106878 7107132 254 0
hScc1 BcellGSE12603 7010512 7011102 590 0
hScc1 BcellGSE12603 7028177 7028542 365 0
hScc1 BcellGSE12603 7058160 7058344 184 0
hScc1 BcellGSE12603 7106961 7108377 1416 0
hScc1 G2GSE9613 6990017 6990909 892 0
p63 keratinocytesGSE17611 6983737 6985392 1655 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-25 hsa-mir-25 7 20036482
hsa-miR-25* hsa-mir-25 7 20036482
hsa-miR-377 hsa-mir-377 14 20036482
hsa-miR-377* hsa-mir-377 14 20036482
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
11904 mRNA LAMA1 chr18 6944675 6947415 230 mRNA LAMA1 chr18 6931887 7107813Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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