AutismKB 2.0

Annotation Detail for HKR1


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Basic Information Top
Gene Symbol:HKR1 ( ZNF875 )
Gene Full Name: HKR1, GLI-Kruppel zinc finger family member
Band: 19q13.13
Quick LinksEntrez ID:284459; OMIM: 165250; Uniprot ID:HKR1_HUMAN; ENSEMBL ID: ENSG00000181666; HGNC ID: 4928
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
32Phosphoserine(CDC2)HMM predict
87Phosphoserine(CK2)HMM predict
108Phosphoserine(ATM)HMM predict
171N-linkedHMM predict
201Phosphoserine(CDK)HMM predict
201Phosphoserine(CDC2)HMM predict
254Phosphotyrosine(SRC)HMM predict
254Phosphotyrosine(Abl)HMM predict
277Phosphoserine(IKK)HMM predict
282Phosphotyrosine(Jak)HMM predict
310Phosphotyrosine(Jak)HMM predict
361Phosphothreonine(PKC)HMM predict
366Phosphotyrosine(Jak)HMM predict
366Phosphotyrosine(Jak)HMM predict
387Phosphothreonine(PKA)HMM predict
389Phosphoserine(IKK)HMM predict
394Phosphotyrosine(Jak)HMM predict
404Phosphoserine(ATM)HMM predict
422Phosphotyrosine(EGFR)HMM predict
422Phosphotyrosine(Jak)HMM predict
450Phosphotyrosine(Jak)HMM predict
483S-palmitoylHMM predict
488Phosphothreonine(PKC)HMM predict
492Phosphothreonine(PKA)HMM predict
539S-palmitoylHMM predict
609Phosphothreonine(PKA)HMM predict
616Phosphotyrosine(Jak)HMM predict
637ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_181786
  • Location:chr19 42517419-42547194
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 42516872 42517820 948 74
P300 T0-glioblastomaGSE21026 42500198 42501112 914 16765
P300 T0-glioblastomaGSE21026 42517192 42517601 409 23
P300 T30-glioblastomaGSE21026 42500141 42501240 1099 16729
P300 T30-glioblastomaGSE21026 42516926 42517874 948 20
PHF8 293TGSE20725 42500391 42500988 597 16730
PHF8 HeLaGSE20725 42500115 42501259 1144 16733
PHF8 Hs68minusFBSGSE20725 42500594 42500947 353 16649
Rb SenescentGSE19898 42500621 42500926 305 16646
TAFII hESGSE17917 42500250 42500870 620 16860
hScc1 BcellGSE12603 42500284 42500979 695 16788
p130 shRbSenescentGSE19898 42500273 42500889 616 16839
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 42553389 42553993 604 6497
ETS1 JurkatGSE17954 42553171 42554566 1395 6674
H3K4me3 colorectalcancer 42559892 42560401 509 12952
H3ac HepG2E 42554029 42554359 330 7000
P300 T30-glioblastomaGSE21026 42553463 42554438 975 6756
PHF8 HeLaGSE20725 42553117 42554659 1542 6694
PHF8 Hs68minusFBSGSE20725 42553475 42554561 1086 6824
VDR GM10855-UnstimGSE22484 42553115 42554458 1343 6592
VDR GM10855-stimGSE22484 42553198 42554423 1225 6616
hScc1 BcellGSE12603 42553317 42553750 433 6339
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 42545564 42545925 361 0
H3K4me3 colorectalcancer 42546418 42546710 292 0
KLF4 hESGSE17917 42517350 42517724 374 0
Oct1 HelaGSE14283 42532836 42532877 41 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018