AutismKB 2.0

Annotation Detail for ANGPT2


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Basic Information Top
Gene Symbol:ANGPT2 ( AGPT2,ANG2 )
Gene Full Name: angiopoietin 2
Band: 8p23.1
Quick LinksEntrez ID:285; OMIM: 601922; Uniprot ID:ANGP2_HUMAN; ENSEMBL ID: ENSG00000091879; HGNC ID: 485
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
89N-linked (GlcNAc...) (Potential).
119N-linked (GlcNAc...) (Potential).
133N-linked (GlcNAc...) (Potential).
151N-linked (GlcNAc...) (Potential).
240N-linked (GlcNAc...) (Potential).
304N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
89N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
119N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
133N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
151N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
240N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
304N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
55Phosphoserine(CK1)HMM predict
58Phosphoserine(CDC2)HMM predict
58Phosphoserine(ATM)HMM predict
60Phosphotyrosine(Jak)HMM predict
60Phosphotyrosine(INSR)HMM predict
73SulfotyrosineHMM predict
89N-linkedHMM predict
90N-linkedHMM predict
100Phosphotyrosine(INSR)HMM predict
119N-linkedHMM predict
133N-linkedHMM predict
151N-linkedHMM predict
164Phosphoserine(CK1)HMM predict
225Phosphoserine(CK2)HMM predict
304N-linkedHMM predict
348N-linkedHMM predict
384Phosphotyrosine(SRC)HMM predict
385Phosphoserine(CK1)HMM predict
414O-linkedHMM predict
417Phosphoserine(ATM)HMM predict
482Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001147
  • Location:chr8 6347600-6408171
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 6383269 6383411 142 0
CTCF G2GSE9613 6395194 6395409 215 0
FOXA1 DLD1GSE12801 6404585 6406024 1439 0
FOXA1 MCF7GSE15244 6405306 6406089 783 0
FoxA1 MCF7MACSdata 6405480 6405798 318 0
KLF4 hESGSE17917 6381109 6381264 155 0
Oct1 H2O2-HelaGSE14283 6364043 6364074 31 0
p63 keratinocytesGSE17611 6361352 6362253 901 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018