Annotation Detail for DLL1

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Basic Information Top

Gene Symbol:	DLL1 ( DELTA1,DL1,Delta )
Gene Full Name:	delta-like 1 (Drosophila)
Band:	6q27
Quick Links	Entrez ID:28514; OMIM: 606582; Uniprot ID:DLL1_HUMAN; ENSEMBL ID: ENSG00000198719; HGNC ID: 2908
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
477	N-linked (GlcNAc...) (Potential).

Location(AA)	Modifications	Resource
477	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	170442443	170442980	537	1090
CTCF	G2	GSE9613	170443516	170444112	596	2193
CTCF	G2	GSE9613	170446409	170447028	619	5097
CTCF	G2	GSE9613	170447361	170447698	337	5908
CTCF	G2	GSE9613	170448133	170448368	235	6629
H3K27me3	colorectal	cancer	170443084	170443958	874	1900
H3K27me3	colorectal	cancer	170444284	170446373	2089	3707
Myc	hES	GSE17917	170447083	170447388	305	5614
Oct4	hES	GSE21916	170446082	170447443	1361	5141
hScc1	Bcell	GSE12603	170446509	170446993	484	5130
hScc1	Bcell	GSE12603	170447361	170448297	936	6208
hScc1	CdLS	GSE12603	170442803	170443267	464	1414

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	170413372	170413582	210	19744
CTCF	G2	GSE9613	170417750	170418755	1005	14968
CTCF	G2	GSE9613	170419529	170419665	136	13624
CTCF	G2	GSE9613	170423716	170423893	177	9416
CTCF	G2	GSE9613	170431637	170431989	352	1408
FOXA1	MCF7	GSE15244	170430784	170431989	1205	1834
FoxA1	MCF7	MACSdata	170430905	170431390	485	2073
RARA	MCF7	GSE15244	170430849	170431601	752	1996
RARG	MCF7	GSE15244	170430748	170431989	1241	1852
TFAP2C	MCF7	GSE21234	170430820	170431873	1053	1874
hScc1	Bcell	GSE12603	170417831	170418638	807	14986

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	170434047	170434983	936
CTCF	G2	GSE9613	170438357	170438900	543
CTCF	G2	GSE9613	170440169	170441883	1714
H3K27me3	colorectal	cancer	170438756	170440028	1272
hScc1	Bcell	GSE12603	170440251	170442339	2088

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-1	hsa-mir-1-2	18	14697198
hsa-miR-1	hsa-mir-1-1	20	14697198
hsa-miR-101	hsa-mir-101-1	1	14697198
hsa-miR-101	hsa-mir-101-2	9	14697198
hsa-miR-130a	hsa-mir-130a	11	14697198
hsa-miR-130a*	hsa-mir-130a	11	14697198
hsa-miR-19a	hsa-mir-19a	13	14697198
hsa-miR-19a*	hsa-mir-19a	13	14697198
hsa-miR-23a	hsa-mir-23a	19	14697198
hsa-miR-23a*	hsa-mir-23a	19	14697198
hsa-miR-23b	hsa-mir-23b	9	14697198
hsa-miR-23b*	hsa-mir-23b	9	14697198
hsa-miR-26a	hsa-mir-26a-1	3	14697198
hsa-miR-26a	hsa-mir-26a-2	12	14697198
hsa-miR-34a	hsa-mir-34a	1	20213410
hsa-miR-34a	hsa-mir-34a	1	14697198
hsa-miR-34a*	hsa-mir-34a	1	20213410
hsa-miR-34a*	hsa-mir-34a	1	14697198
hsa-miR-34b	hsa-mir-34b	11	20213410
hsa-miR-34b*	hsa-mir-34b	11	20213410
hsa-miR-34c-3p	hsa-mir-34c	11	20213410
hsa-miR-34c-5p	hsa-mir-34c	11	20213410

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
613	mRNA repression	TRUE	miR-34	DLL1	in vitro reporter gene assay (Luciferase)	14697198
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000198719		n_a	n_a	n_a	n_a	n_a

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018