AutismKB 2.0

Annotation Detail for GRK4


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Basic Information Top
Gene Symbol:GRK4 ( GPRK2L,GPRK4,GRK4a,IT11 )
Gene Full Name: G protein-coupled receptor kinase 4
Band: 4p16.3
Quick LinksEntrez ID:2868; OMIM: 137026; Uniprot ID:GRK4_HUMAN; ENSEMBL ID: ENSG00000125388; HGNC ID: 4543
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
162SulfotyrosineHMM predict
162Phosphotyrosine(Syk)HMM predict
169Phosphoserine(ATM)HMM predict
352Phosphotyrosine(INSR)HMM predict
404N-linkedHMM predict
419Phosphoserine(IKK)HMM predict
474Phosphotyrosine(Jak)HMM predict
500Phosphotyrosine(Syk)HMM predict
500Phosphotyrosine(EGFR)HMM predict
526N-linkedHMM predict
530Phosphoserine(CK2)HMM predict
544Phosphothreonine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001004056
  • Location:chr4 2935140-3012271
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 Hs68plusFBSGSE20725 2933978 2936207 2229 48
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3019005 3019215 210 6839
CTCF CD4SISSRdata 3019005 3019215 210 6839
CTCF G2GSE9613 3012486 3013676 1190 810
RNAII Tamoxifen-MCF7GSE14664 3012741 3012790 49 494
RNAII Tamoxifen-MCF7GSE14664 3016874 3016965 91 4648
RNAII Tamoxifen-MCF7GSE14664 3017229 3017381 152 5034
RNAII Tamoxifen-MCF7GSE14664 3017448 3017519 71 5212
RNAII Tamoxifen-MCF7GSE14664 3018095 3018143 48 5848
STAT1 HeLaGSE12782 3014463 3015678 1215 2799
STAT1 HeLaGSE12783 3014497 3015644 1147 2799
STAT1 IFNSISSRdata 3014666 3015476 810 2800
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 2950033 2950305 272 0
CTCF CD4GSE12889 3008893 3009194 301 0
CTCF CD4SISSRdata 2950033 2950305 272 0
CTCF CD4SISSRdata 3008893 3009194 301 0
CTCF HelaGSE12889 2950029 2950243 214 0
CTCF G2GSE9613 2935283 2935784 501 0
CTCF G2GSE9613 2936791 2937014 223 0
CTCF G2GSE9613 2944915 2945312 397 0
CTCF G2GSE9613 2953836 2953982 146 0
CTCF G2GSE9613 2978306 2978533 227 0
CTCF G2GSE9613 2980981 2981200 219 0
CTCF G2GSE9613 2988422 2989154 732 0
CTCF G2GSE9613 2992908 2993119 211 0
CTCF G2GSE9613 3001057 3001240 183 0
CTCF G2GSE9613 3002122 3003435 1313 0
CTCF G2GSE9613 3003980 3004353 373 0
CTCF G2GSE9613 3007032 3007871 839 0
CTCF G2GSE9613 3008460 3009065 605 0
CTCF G2GSE9613 3009472 3009934 462 0
H3ac HepG2E 3008320 3009065 745 0
H3ac HepG2E 3010084 3010415 331 0
RNAII Tamoxifen-MCF7GSE14664 3009472 3009556 84 0
STAT1 IFNSISSRdata 3008693 3009115 422 0
hScc1 BcellGSE12603 2935315 2935860 545 0
hScc1 BcellGSE12603 2980981 2981357 376 0
hScc1 BcellGSE12603 3007372 3007692 320 0
hScc1 BcellGSE12603 3008166 3009065 899 0
hScc1 CdLSGSE12603 2980981 2981283 302 0
hScc1 CdLSGSE12603 3008530 3009065 535 0
hScc1 G2GSE9613 3008358 3009065 707 0
p63 keratinocytesGSE17611 2980976 2981956 980 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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