Annotation Detail for LIN9

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Basic Information Top

Gene Symbol:	LIN9 ( BARA,BARPsv,Lin-9,TGS,TGS1 )
Gene Full Name:	lin-9 homolog (C. elegans)
Band:	1q42.12
Quick Links	Entrez ID:286826; OMIM: 609375; Uniprot ID:LIN9_HUMAN; ENSEMBL ID: ENSG00000183814; HGNC ID: 30830
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:7 results
Experimental PTM Sites from dbPTM:1 results
Predicted PTM Sites by profile HMM from dbPTM:14 results

Location(AA)	Modification
2	N-acetylalanine.
65	Phosphoserine.
96	Phosphothreonine.
297	Phosphothreonine.
304	Phosphothreonine.
309	Phosphoserine.
321	Phosphoserine.

Location(AA)	Modification	Resource
46	N-linked	HMM predict
65	Phosphoserine(CK1)	HMM predict
76	Phosphoserine(CDK)	HMM predict
210	Methyllysine	HMM predict
227	Phosphothreonine(PKA)	HMM predict
249	N-linked	HMM predict
269	Sulfotyrosine	HMM predict
390	Phosphothreonine(PKA)	HMM predict
447	N-linked	HMM predict
448	Phosphoserine(CK1)	HMM predict
449	O-linked	HMM predict
459	N-linked	HMM predict
506	N-linked	HMM predict
512	N-linked	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_173083
Location:chr1 224485487-224563820
strand:-

Upstream the gene:4 results
Downstream the gene:0 results
Inside the gene:17 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Fos	K562	GSE19551	224575134	224575655	521	11574
H3K4me3	colorectal	cancer	224564072	224564656	584	544
TAF	Hela	GSE8489	224564154	224565059	905	786
TAF	k562	GSE8489	224563992	224565774	1782	1063

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	224562774	224563444	670	0
E2F4	G0	GSE7516	224562774	224563713	939	0
H3K4me3	colorectal	cancer	224562244	224562808	564	0
LIN9	G0	GSE7516	224562585	224563754	1169	0
LIN9	S	GSE7516	224562808	224563790	982	0
P300	T30-glioblastoma	GSE21026	224562904	224564675	1771	0
PHF8	293T	GSE20725	224562363	224564281	1918	0
PHF8	HeLa	GSE20725	224562591	224564515	1924	0
Rb	Quiescent	GSE19898	224563194	224563616	422	0
TAF	k562	GSE8489	224559844	224560344	500	0
TAF	k562	GSE8489	224560688	224561637	949	0
TAF	k562	GSE8489	224562244	224562702	458	0
TAFII	hES	GSE17917	224563035	224563806	771	0
p130	Quiescent	GSE19898	224563095	224563742	647	0
p130	Senescent	GSE19898	224563147	224563635	488	0
p130	shRbQuiescent	GSE19898	224563095	224563696	601	0
p130	shRbSenescent	GSE19898	224562954	224563627	673	0

Validated miRNA targets

miR Walk:14 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-320a	hsa-mir-320a	8	18852463
hsa-miR-320a	hsa-mir-320a	8	18852463
hsa-miR-320b	hsa-mir-320b-1	1	18852463
hsa-miR-320b	hsa-mir-320b-2	1	18852463
hsa-miR-320b	hsa-mir-320b-1	1	18852463
hsa-miR-320b	hsa-mir-320b-2	1	18852463
hsa-miR-320c	hsa-mir-320c-1	18	18852463
hsa-miR-320c	hsa-mir-320c-2	18	18852463
hsa-miR-320c	hsa-mir-320c-1	18	18852463
hsa-miR-320c	hsa-mir-320c-2	18	18852463
hsa-miR-320d	hsa-mir-320d-1	13	18852463
hsa-miR-320d	hsa-mir-320d-2	X	18852463
hsa-miR-320d	hsa-mir-320d-1	13	18852463
hsa-miR-320d	hsa-mir-320d-2	X	18852463

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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