AutismKB 2.0

Annotation Detail for GPS1


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Basic Information Top
Gene Symbol:GPS1 ( COPS1,CSN1,MGC71287 )
Gene Full Name: G protein pathway suppressor 1
Band: 17q25.3
Quick LinksEntrez ID:2873; OMIM: 601934; Uniprot ID:CSN1_HUMAN; ENSEMBL ID: ENSG00000169727; HGNC ID: 4549
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
377Phosphotyrosine.
467N6-acetyllysine.
468Phosphoserine.
474Phosphoserine.
479Phosphothreonine.
483Phosphoserine.
488Phosphoserine.
Location(AA) Modifications Resource
459Phosphothreonine.Swiss-Prot 53.0
463Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
83Phosphoserine(PKG)HMM predict
132Phosphotyrosine(INSR)HMM predict
207Phosphoserine(CK2)HMM predict
265Phosphoserine(CDC2)HMM predict
265Phosphoserine(CDK)HMM predict
337Phosphotyrosine(Jak)HMM predict
374N-linkedHMM predict
459Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004127
  • Location:chr17 77603051-77608634
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 77607702 77608444 742 0
ETS1 JurkatGSE17954 77602843 77603463 620 0
Oct1 H2O2-HelaGSE14283 77606404 77606431 27 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018