Annotation Detail for GRIA2
Basic Information Top
| Gene Symbol: | GRIA2 ( GLUR2,GLURB,GluA2,GluR-K2,HBGR2 ) |
|---|---|
| Gene Full Name: | glutamate receptor, ionotropic, AMPA 2 |
| Band: | 4q32.1 |
| Quick Links | Entrez ID:2891; OMIM: 138247; Uniprot ID:GRIA2_HUMAN; ENSEMBL ID: ENSG00000120251; HGNC ID: 4572 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 256 | N-linked (GlcNAc...) (Potential). | |
| 370 | N-linked (GlcNAc...) (Potential). | |
| 406 | N-linked (GlcNAc...) (Potential). | |
| 413 | N-linked (GlcNAc...) (Potential). | |
| 683 | Phosphoserine; by PKC (By similarity). | |
| 717 | Phosphoserine; by PKG (By similarity). | |
| 869 | Phosphotyrosine (By similarity). | |
| 876 | Phosphotyrosine (By similarity). | |
| 880 | Phosphoserine (By similarity). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 256 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 370 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 406 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 413 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 610 | S-palmitoyl cysteine (By similarity). | Swiss-Prot 53.0 |
| 836 | S-palmitoyl cysteine (By similarity). | Swiss-Prot 53.0 |
| 880 | Phosphoserine | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 41 | Phosphotyrosine(EGFR) | HMM predict |
| 142 | Sulfotyrosine | HMM predict |
| 143 | Sulfotyrosine | HMM predict |
| 192 | Phosphotyrosine(EGFR) | HMM predict |
| 256 | N-linked | HMM predict |
| 279 | Phosphothreonine(PKC) | HMM predict |
| 292 | O-linked | HMM predict |
| 406 | N-linked | HMM predict |
| 413 | N-linked | HMM predict |
| 420 | O-linked | HMM predict |
| 585 | Phosphoserine(IKK) | HMM predict |
| 652 | Phosphoserine(CAMK2) | HMM predict |
| 661 | Phosphoserine(CK1) | HMM predict |
| 683 | Phosphoserine(PKC) | HMM predict |
| 717 | Phosphoserine(PKC) | HMM predict |
| 717 | Phosphoserine(PKG) | HMM predict |
| 801 | O-linked | HMM predict |
| 856 | N-linked | HMM predict |
| 860 | Phosphoserine(ATM) | HMM predict |
| 860 | Phosphoserine(CK1) | HMM predict |
| 862 | N-linked | HMM predict |
| 873 | Phosphotyrosine(Syk) | HMM predict |
- RefSeq ID: NM_000826
- Location:chr4 158361296-158506673
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 158345152 | 158345494 | 342 | 15974 |
| CTCF | G2 | GSE9613 | 158360787 | 158361484 | 697 | 161 |
| NRSF | Jurkat | GSE13047 | 158360620 | 158361633 | 1013 | 170 |
| NRSF-mono | Jurkat | QuESTdata | 158360648 | 158361587 | 939 | 179 |
| NRSF-poly | Jurkat | QuESTdata | 158360620 | 158361548 | 928 | 213 |
| TFAP2C | MCF7 | GSE21234 | 158360722 | 158361083 | 361 | 394 |
| hScc1 | Bcell | GSE12603 | 158345261 | 158345494 | 233 | 15919 |
| hScc1 | Bcell | GSE12603 | 158360858 | 158361301 | 443 | 217 |
| hScc1 | CdLS | GSE12603 | 158345109 | 158345494 | 385 | 15995 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Sox2 | hES | GSE18292 | 158516729 | 158516942 | 213 | 10162 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 158362666 | 158363040 | 374 | 0 |
| CTCF | G2 | GSE9613 | 158384635 | 158384812 | 177 | 0 |
| NRSF | mAb | Jurkat | 158359643 | 158364478 | 4835 | 0 |
| PAX3-FKHR | Rh4 | GSE19063 | 158497711 | 158499318 | 1607 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-181b | hsa-mir-181b-1 | 1 | 20347265 |
| hsa-miR-181b | hsa-mir-181b-2 | 9 | 20347265 |
| hsa-miR-181b | hsa-mir-181b-1 | 1 | 18184693 |
| hsa-miR-181b | hsa-mir-181b-2 | 9 | 18184693 |
| hsa-miR-198 | hsa-mir-198 | 0 | 20347265 |
| hsa-miR-206 | hsa-mir-206 | 6 | 20347265 |
| hsa-miR-24 | hsa-mir-24-1 | 9 | 20347265 |
| hsa-miR-24 | hsa-mir-24-2 | 19 | 20347265 |
| hsa-miR-24-1* | hsa-mir-24-1 | 9 | 20347265 |
| hsa-miR-24-2* | hsa-mir-24-2 | 19 | 20347265 |
| hsa-miR-26b | hsa-mir-26b | 2 | 20347265 |
| hsa-miR-26b* | hsa-mir-26b | 2 | 20347265 |
| hsa-miR-30a | hsa-mir-30a | 6 | 20582287 |
| hsa-miR-30a* | hsa-mir-30a | 6 | 20582287 |
| hsa-miR-30b | hsa-mir-30b | 8 | 20347265 |
| hsa-miR-30b | hsa-mir-30b | 8 | 20582287 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 20347265 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 20582287 |
| hsa-miR-30c | hsa-mir-30c-2 | 6 | 20582287 |
| hsa-miR-30c | hsa-mir-30c-1 | 1 | 20582287 |
| hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 20582287 |
| hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 20582287 |
| hsa-miR-30d | hsa-mir-30d | 8 | 20582287 |
| hsa-miR-30d* | hsa-mir-30d | 8 | 20582287 |
| hsa-miR-30e | hsa-mir-30e | 1 | 20347265 |
| hsa-miR-30e | hsa-mir-30e | 1 | 20582287 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 20347265 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 20582287 |
| hsa-miR-92a | hsa-mir-92a-1 | 13 | 20347265 |
| hsa-miR-92a | hsa-mir-92a-2 | X | 20347265 |
| hsa-miR-92a-1* | hsa-mir-92a-1 | 13 | 20347265 |
| hsa-miR-92a-2* | hsa-mir-92a-2 | X | 20347265 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 497 | Unknown | TRUE | miR-181b | GRIA2 | Luciferase assay - mutant MRE | 18184693 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000120251 | cortical grey matter from the superior temporal gyrus | schizophrenia | up regulated | "lymphocyte, muscle cell" | "malignant tumour, benign tumour, carcinoma" |
Cis-Nats regulation