AutismKB 2.0

Annotation Detail for GRIK4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GRIK4 ( EAA1,GRIK,KA1 )
Gene Full Name: glutamate receptor, ionotropic, kainate 4
Band: 11q23.3
Quick LinksEntrez ID:2900; OMIM: 600282; Uniprot ID:GRIK4_HUMAN; ENSEMBL ID: ENSG00000149403; HGNC ID: 4582
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
158N-linked (GlcNAc...) (Potential).
220N-linked (GlcNAc...) (Potential).
272N-linked (GlcNAc...) (Potential).
286N-linked (GlcNAc...) (Potential).
323N-linked (GlcNAc...) (Potential).
408N-linked (GlcNAc...) (Potential).
415N-linked (GlcNAc...) (Potential).
479N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
158N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
220N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
272N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
286N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
323N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
408N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
415N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
479N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
77Phosphotyrosine(Syk)HMM predict
77Phosphotyrosine(EGFR)HMM predict
77Phosphotyrosine(SRC)HMM predict
77Phosphotyrosine(INSR)HMM predict
99O-linkedHMM predict
100Phosphoserine(ATM)HMM predict
100O-linkedHMM predict
100Phosphoserine(CDC2)HMM predict
135Phosphothreonine(PKA)HMM predict
158N-linkedHMM predict
201Phosphothreonine(MAPK)HMM predict
201Phosphothreonine(CDK)HMM predict
220N-linkedHMM predict
272N-linkedHMM predict
286N-linkedHMM predict
292N-linkedHMM predict
325Phosphoserine(ATM)HMM predict
405Phosphotyrosine(INSR)HMM predict
408N-linkedHMM predict
415N-linkedHMM predict
422O-linkedHMM predict
428Phosphotyrosine(Syk)HMM predict
473Phosphotyrosine(SRC)HMM predict
473Phosphotyrosine(Abl)HMM predict
473Phosphotyrosine(INSR)HMM predict
473PhosphotyrosineHMM predict
479N-linkedHMM predict
686Phosphothreonine(PKC)HMM predict
729Phosphotyrosine(Jak)HMM predict
730Phosphotyrosine(Jak)HMM predict
736N-linkedHMM predict
936Phosphoserine(CDC2)HMM predict
936Phosphoserine(CDK)HMM predict
940Phosphoserine(CK1)HMM predict
943Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014619
  • Location:chr11 120036237-120362178
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM12878GSE19485 120032962 120034819 1857 2347
NFkBII GM12892GSE19485 120033290 120034807 1517 2189
NRSF JurkatGSE13047 120028611 120029461 850 7202
NRSF mAbJurkat 120028249 120030096 1847 7065
NRSF mAbJurkat 120030797 120031956 1159 4861
NRSF-mono JurkatQuESTdata 120028616 120029394 778 7233
NRSF pAbJurkat 120028249 120028811 562 7708
NRSF pAbJurkat 120029254 120029798 544 6712
NRSF-poly JurkatQuESTdata 120028627 120029284 657 7282
Nanog ESGSE20650 120021445 120022321 876 14355
Oct1 H2O2-HelaGSE14283 120035348 120035378 30 875
Oct1 HelaGSE14283 120035349 120035385 36 871
Oct1 HelaGSE14283 120035787 120035820 33 434
STAT1 HeLaGSE12783 120016813 120017912 1099 18875
TFAP2C MCF7GSE21234 120024785 120025209 424 11241
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 120373941 120373974 33 11779
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 120050257 120051208 951 0
CTCF CD4GSE12889 120060929 120061139 210 0
CTCF CD4GSE12889 120091346 120091542 196 0
CTCF CD4GSE12889 120178169 120178545 376 0
CTCF CD4GSE12889 120305661 120305882 221 0
CTCF CD4GSE12889 120310147 120310295 148 0
CTCF CD4GSE12889 120328707 120329051 344 0
CTCF CD4GSE12889 120361953 120362103 150 0
CTCF CD4SISSRdata 120060929 120061139 210 0
CTCF CD4SISSRdata 120091346 120091542 196 0
CTCF CD4SISSRdata 120178169 120178545 376 0
CTCF CD4SISSRdata 120305661 120305882 221 0
CTCF CD4SISSRdata 120310147 120310295 148 0
CTCF CD4SISSRdata 120328707 120329051 344 0
CTCF CD4SISSRdata 120361953 120362103 150 0
CTCF JurkatGSE12889 120178246 120178429 183 0
ER E2-MCF7GSE14664 120049031 120049131 100 0
ER E2-MCF7GSE14664 120156799 120156832 33 0
ER MCF7GSE19013 120039046 120039632 586 0
ER MCF7GSE19013 120188445 120189419 974 0
ER MCF7GSE19013 120306862 120307505 643 0
ER MCF7GSE19013 120308832 120309328 496 0
ER MCF7GSE19013 120328244 120328950 706 0
FOXA1 MCF7GSE15244 120183436 120184030 594 0
FOXA1 MCF7GSE15244 120288405 120288927 522 0
Fos K562GSE19551 120218158 120218411 253 0
GABP HelaGSE8489 120356636 120357094 458 0
GATA3 MCF7GSE15244 120086387 120087452 1065 0
KLF4 hESGSE17917 120260484 120260652 168 0
NRSF JurkatGSE13047 120122323 120122709 386 0
NRSF-mono JurkatQuESTdata 120122184 120122708 524 0
NRSF-mono JurkatQuESTdata 120230876 120231238 362 0
NRSF-mono JurkatQuESTdata 120276527 120276997 470 0
NRSF pAbJurkat 120073585 120073975 390 0
NRSF pAbJurkat 120169371 120170291 920 0
NRSF pAbJurkat 120259833 120260552 719 0
NRSF-poly JurkatQuESTdata 120122329 120122639 310 0
NRSF-poly JurkatQuESTdata 120231016 120231367 351 0
Nanog ESGSE20650 120147348 120147918 570 0
Nanog hESGSE18292 120147421 120147709 288 0
Oct1 H2O2-HelaGSE14283 120081593 120081630 37 0
Oct1 H2O2-HelaGSE14283 120123981 120124020 39 0
Oct1 H2O2-HelaGSE14283 120338621 120338655 34 0
Oct1 HelaGSE14283 120048850 120048896 46 0
Oct1 HelaGSE14283 120081566 120081621 55 0
Oct1 HelaGSE14283 120084187 120084263 76 0
Oct1 HelaGSE14283 120123984 120124015 31 0
Oct1 HelaGSE14283 120152037 120152072 35 0
Oct1 HelaGSE14283 120152172 120152202 30 0
Oct1 HelaGSE14283 120157387 120157424 37 0
Oct1 HelaGSE14283 120162476 120162540 64 0
Oct1 HelaGSE14283 120170766 120170809 43 0
Oct1 HelaGSE14283 120253658 120253731 73 0
Oct1 HelaGSE14283 120276620 120276694 74 0
Oct1 HelaGSE14283 120280710 120280748 38 0
Oct1 HelaGSE14283 120283810 120283863 53 0
Oct1 HelaGSE14283 120338621 120338655 34 0
Oct1 HelaGSE14283 120349774 120349804 30 0
P300 T30-glioblastomaGSE21026 120050134 120051311 1177 0
P300 T30-glioblastomaGSE21026 120182999 120184069 1070 0
RARA MCF7GSE15244 120183472 120184030 558 0
RARA MCF7GSE15244 120188633 120189429 796 0
RARA MCF7GSE15244 120284787 120285146 359 0
RARG MCF7GSE15244 120122792 120123258 466 0
RARG MCF7GSE15244 120183508 120184030 522 0
RARG MCF7GSE15244 120188707 120189351 644 0
RARG MCF7GSE15244 120284787 120284960 173 0
TFAP2C MCF7GSE21234 120086346 120086824 478 0
TFAP2C MCF7GSE21234 120191522 120192109 587 0
TFAP2C MCF7GSE21234 120239386 120239791 405 0
TFAP2C MCF7GSE21234 120243309 120243812 503 0
TFAP2C MCF7GSE21234 120253791 120254205 414 0
TFAP2C MCF7GSE21234 120279976 120280481 505 0
TFAP2C MCF7GSE21234 120284275 120285232 957 0
TFAP2C MCF7GSE21234 120329865 120330241 376 0
USF1 HepG2E 120085212 120086774 1562 0
USF1 HepG2E 120087346 120088352 1006 0
USF2 HepG2E 120085760 120086623 863 0
hScc1 BcellGSE12603 120035950 120036609 659 0
hScc1 BcellGSE12603 120060922 120061106 184 0
hScc1 BcellGSE12603 120091072 120091595 523 0
hScc1 BcellGSE12603 120177936 120178579 643 0
hScc1 BcellGSE12603 120305231 120306238 1007 0
hScc1 BcellGSE12603 120328408 120329250 842 0
hScc1 BcellGSE12603 120361739 120362357 618 0
hScc1 CdLSGSE12603 120060922 120061106 184 0
hScc1 CdLSGSE12603 120090932 120091405 473 0
hScc1 CdLSGSE12603 120177903 120178791 888 0
hScc1 CdLSGSE12603 120211663 120212057 394 0
hScc1 CdLSGSE12603 120288188 120289163 975 0
hScc1 CdLSGSE12603 120305418 120306238 820 0
hScc1 CdLSGSE12603 120310151 120310347 196 0
hScc1 CdLSGSE12603 120328372 120329174 802 0
hScc1 G2GSE9613 120090932 120091334 402 0
hScc1 G2GSE9613 120178139 120178615 476 0
hScc1 G2GSE9613 120305275 120305786 511 0
hScc1 G2GSE9613 120328294 120329174 880 0
p63 keratinocytesGSE17611 120122485 120123767 1282 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
5314 mRNA GRIK4 chr11 120036237 120362179 26860 HTC chr11 120243856 120270716 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved