AutismKB 2.0

Annotation Detail for GRIN2A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GRIN2A ( NMDAR2A,NR2A )
Gene Full Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Band: 16p13.2
Quick LinksEntrez ID:2903; OMIM: 138253; Uniprot ID:NMDE1_HUMAN; ENSEMBL ID: ENSG00000183454; HGNC ID: 4585
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
75N-linked (GlcNAc...) (Potential).
340N-linked (GlcNAc...) (Potential).
380N-linked (GlcNAc...) (Potential).
443N-linked (GlcNAc...) (Potential).
444N-linked (GlcNAc...) (Potential).
541N-linked (GlcNAc...) (Potential).
888Phosphothreonine (By similarity).
912Phosphoserine.
917Phosphoserine.
929Phosphoserine (By similarity).
943Phosphotyrosine (By similarity).
1025Phosphoserine (By similarity).
1337Phosphoserine.
1459Phosphoserine (By similarity).
1464PDZ-binding (By similarity).
Location(AA) Modifications Resource
75N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
340N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
380N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
443N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
444N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
541N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
888Phosphothreonine (By similarity).Swiss-Prot 53.0
917Phosphoserine (By similarity).Swiss-Prot 53.0
929Phosphoserine (By similarity).Swiss-Prot 53.0
1025Phosphoserine (By similarity).Swiss-Prot 53.0
1232Phosphoserine (CDK
1337Phosphoserine.Swiss-Prot 53.0
1459Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
75N-linkedHMM predict
312Phosphotyrosine(Jak)HMM predict
340N-linkedHMM predict
380N-linkedHMM predict
395Phosphoserine(IKK)HMM predict
444N-linkedHMM predict
447N-linkedHMM predict
478Phosphotyrosine(Jak)HMM predict
502Phosphotyrosine(EGFR)HMM predict
541N-linkedHMM predict
614N-linkedHMM predict
615N-linkedHMM predict
625Phosphothreonine(PKC)HMM predict
676Phosphotyrosine(Syk)HMM predict
687N-linkedHMM predict
693N-linkedHMM predict
769Phosphoserine(CDC2)HMM predict
810Phosphoserine(ATM)HMM predict
868Phosphotyrosine(INSR)HMM predict
882Phosphoserine(CDC2)HMM predict
886N-linkedHMM predict
903N-linkedHMM predict
909N-linkedHMM predict
911N-linkedHMM predict
917Phosphoserine(CDC2)HMM predict
989N-linkedHMM predict
992N-linkedHMM predict
994N-linkedHMM predict
1025Phosphoserine(IKK)HMM predict
1027Phosphoserine(ATM)HMM predict
1032Phosphoserine(ATM)HMM predict
1041N-linkedHMM predict
1045Phosphoserine(PKA)HMM predict
1045Phosphoserine(IKK)HMM predict
1051Phosphotyrosine(INSR)HMM predict
1062Phosphoserine(CK1)HMM predict
1108PhosphothreonineHMM predict
1112Phosphoserine(CDC2)HMM predict
1138N-linkedHMM predict
1144N-linkedHMM predict
1151Phosphotyrosine(Syk)HMM predict
1192Phosphothreonine(PKC)HMM predict
1201Phosphoserine(IKK)HMM predict
1210N-linkedHMM predict
1232Phosphoserine(CDK)HMM predict
1291Phosphoserine(CAMK2)HMM predict
1330Phosphoserine(ATM)HMM predict
1356Phosphoserine(PKG)HMM predict
1393Phosphoserine(ATM)HMM predict
1397N-linkedHMM predict
1410Phosphoserine(PKB)HMM predict
1459Phosphoserine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000833
  • Location:chr16 9762922-10184111
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 10202185 10202316 131 18139
H3K27me3 colorectalcancer 10184876 10185311 435 982
NRSF-mono JurkatQuESTdata 10184642 10184983 341 701
Nanog ESGSE20650 10190562 10190962 400 6651
RNAII Tamoxifen-MCF7GSE14664 10203002 10203088 86 18934
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
KLF4 hESGSE17917 9753535 9753783 248 9264
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 9916101 9916314 213 0
CBP T30-glioblastomaGSE21026 10122153 10123536 1383 0
CBP T30-glioblastomaGSE21026 9798470 9799123 653 0
CTCF CD4GSE12889 10183026 10183169 143 0
CTCF CD4SISSRdata 10183026 10183169 143 0
CTCF HelaGSE12889 10124014 10124190 176 0
CTCF HelaGSE12889 10183015 10183191 176 0
CTCF G2GSE9613 10032883 10033178 295 0
CTCF G2GSE9613 10181813 10182492 679 0
CTCF G2GSE9613 10182988 10183491 503 0
CTCF G2GSE9613 9805710 9806113 403 0
ER E2-MCF7GSE14664 10061649 10061684 35 0
ER E2-MCF7GSE14664 9866309 9866353 44 0
ER E2-MCF7GSE14664 9910585 9910617 32 0
ER E2-MCF7GSE14664 9979841 9979886 45 0
ER Fulvestrant-MCF7GSE14664 10087961 10088011 50 0
ER Fulvestrant-MCF7GSE14664 9866313 9866360 47 0
ER Fulvestrant-MCF7GSE14664 9977677 9977711 34 0
Fos K562GSE19551 9789163 9789465 302 0
Myc K562GSE19551 9789173 9789433 260 0
NFkBII GM12878GSE19485 9914984 9916505 1521 0
NRSF JurkatGSE13047 9837364 9838476 1112 0
NRSF mAbJurkat 9827855 9828467 612 0
NRSF mAbJurkat 9833613 9835076 1463 0
NRSF mAbJurkat 9835381 9835689 308 0
NRSF mAbJurkat 9836040 9839564 3524 0
NRSF mAbJurkat 9839901 9841191 1290 0
NRSF mAbJurkat 9841866 9842448 582 0
NRSF mAbJurkat 9842804 9843285 481 0
NRSF-mono JurkatQuESTdata 9837415 9838189 774 0
NRSF pAbJurkat 9837586 9839564 1978 0
NRSF-poly JurkatQuESTdata 9837364 9838129 765 0
Nanog ESGSE20650 9835284 9835870 586 0
Nanog hESGSE18292 10009498 10010061 563 0
Nanog hESGSE18292 10077550 10077748 198 0
Oct1 H2O2-HelaGSE14283 10090199 10090234 35 0
Oct1 H2O2-HelaGSE14283 9942470 9942498 28 0
Oct1 H2O2-HelaGSE14283 9967379 9967406 27 0
Oct1 H2O2-HelaGSE14283 9968140 9968168 28 0
Oct1 H2O2-HelaGSE14283 9977676 9977712 36 0
Oct1 HelaGSE14283 10031199 10031228 29 0
Oct1 HelaGSE14283 10090168 10090236 68 0
Oct1 HelaGSE14283 9768122 9768163 41 0
Oct1 HelaGSE14283 9773625 9773662 37 0
Oct1 HelaGSE14283 9866317 9866351 34 0
Oct1 HelaGSE14283 9880710 9880743 33 0
Oct1 HelaGSE14283 9910580 9910657 77 0
Oct1 HelaGSE14283 9936975 9937010 35 0
Oct1 HelaGSE14283 9937354 9937387 33 0
Oct1 HelaGSE14283 9950802 9950841 39 0
Oct1 HelaGSE14283 9967372 9967435 63 0
Oct1 HelaGSE14283 9977678 9977712 34 0
Oct4 hESGSE17917 9947453 9947682 229 0
Oct4 hESGSE21916 9947327 9947880 553 0
P300 T30-glioblastomaGSE21026 10115497 10116537 1040 0
P300 T30-glioblastomaGSE21026 10122247 10123557 1310 0
P300 T30-glioblastomaGSE21026 10127746 10128951 1205 0
P300 T30-glioblastomaGSE21026 9798415 9799469 1054 0
P300 T30-glioblastomaGSE21026 9968077 9968658 581 0
RNAII Tamoxifen-MCF7GSE14664 9967374 9967409 35 0
Rb GrowingGSE19898 9883321 9883516 195 0
Rb GrowingGSE19898 9898764 9898934 170 0
TFAP2C MCF7GSE21234 10081607 10082235 628 0
TFAP2C MCF7GSE21234 10179432 10179857 425 0
hScc1 BcellGSE12603 10022159 10022842 683 0
hScc1 BcellGSE12603 10181558 10184139 2581 0
hScc1 BcellGSE12603 9811462 9811725 263 0
hScc1 CdLSGSE12603 10181740 10183524 1784 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125b hsa-mir-125b-1 11 20159450
hsa-miR-125b hsa-mir-125b-2 21 20159450
hsa-miR-132 hsa-mir-132 17 20159450
hsa-miR-132 hsa-mir-132 17 19958814
hsa-miR-132* hsa-mir-132 17 20159450
hsa-miR-132* hsa-mir-132 17 19958814
hsa-miR-9 hsa-mir-9-1 1 19958814
hsa-miR-9 hsa-mir-9-2 5 19958814
hsa-miR-9 hsa-mir-9-3 15 19958814
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved