Annotation Detail for METTL5

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	METTL5 ( FLJ10459,HSPC133 )
Gene Full Name:	methyltransferase like 5
Band:	2q31.1
Quick Links	Entrez ID:29081; OMIM: NA; Uniprot ID:METL5_HUMAN; ENSEMBL ID: ENSG00000138382; HGNC ID: 25006
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:4 results

No data

Location(AA)	Modification	Resource
31	Phosphothreonine(PKC)	HMM predict
47	Phosphotyrosine(Syk)	HMM predict
155	O-linked	HMM predict
161	Phosphothreonine(PKC)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_014168
Location:chr2 170376515-170389598
strand:-

Upstream the gene:15 results
Downstream the gene:0 results
Inside the gene:7 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	170389463	170389980	517	123
CTCF	CD4	SISSRdata	170389463	170389980	517	123
CTCF	G2	GSE9613	170389258	170390093	835	77
CTCF	G2	GSE9613	170392088	170393179	1091	3035
H3K4me3	colorectal	cancer	170392927	170394153	1226	3942
H3ac	HepG2	E	170392849	170393811	962	3732
Myc	hES	GSE17917	170389652	170389957	305	206
TAF	Hela	GSE8489	170390897	170391459	562	1580
TAF	k562	GSE8489	170390897	170391459	562	1580
TAF	k562	GSE8489	170392994	170394153	1159	3975
hScc1	Bcell	GSE12603	170389360	170390093	733	128
hScc1	Bcell	GSE12603	170392088	170392771	683	2831
hScc1	CdLS	GSE12603	170389360	170390093	733	128
hScc1	G2	GSE9613	170389360	170390093	733	128
p130	shRbSenescent	GSE19898	170389563	170389915	352	141

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3K4me3	colorectal	cancer	170388716	170389360	644	0
H3ac	HepG2	E	170387328	170387712	384	0
H3ac	HepG2	E	170388611	170389514	903	0
Oct1	H2O2-Hela	GSE14283	170380839	170380869	30	0
Oct1	Hela	GSE14283	170380833	170380909	76	0
PHF8	HeLa	GSE20725	170389016	170390168	1152	0
PolII	HeLa	GSE12783	170388857	170390235	1378	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
15252	mRNA	SSB	chr2	170480895	170494082	62	mRNA	METTL5	chr2	170492097	170506922	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved