AutismKB 2.0

Annotation Detail for DDX25


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DDX25 ( GRTH )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
Band: 11q24.2
Quick LinksEntrez ID:29118; OMIM: 607663; Uniprot ID:DDX25_HUMAN; ENSEMBL ID: ENSG00000109832; HGNC ID: 18698
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
74Nuclear export signal (By similarity).
114Nuclear localization signal (By
125Q motif.
250DEAD box.
Location(AA) Modifications Resource
Location(AA) Modification Resource
26Phosphoserine(ATM)HMM predict
91Phosphoserine(MAPK)HMM predict
145Phosphoserine(IKK)HMM predict
259Phosphoserine(ATM)HMM predict
271Phosphoserine(IKK)HMM predict
425Phosphotyrosine(Syk)HMM predict
425SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013264
  • Location:chr11 125279612-125298212
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 125278768 125279675 907 391
NRSF JurkatGSE13047 125277880 125280092 2212 627
NRSF-mono JurkatQuESTdata 125277947 125280091 2144 594
NRSF-poly JurkatQuESTdata 125277996 125280069 2073 580
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 125298226 125298532 306 167
CTCF CD4SISSRdata 125298226 125298532 306 167
CTCF JurkatGSE12889 125298252 125298536 284 182
Nanog hESGSE18292 125306423 125306850 427 8424
STAT1 IFNSISSRdata 125298123 125298563 440 131
TAFII hESGSE17917 125298149 125298497 348 111
hScc1 BcellGSE12603 125298130 125298542 412 124
hScc1 CdLSGSE12603 125297868 125298613 745 28
hScc1 G2GSE9613 125298012 125299058 1046 323
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018