AutismKB 2.0

Annotation Detail for GRM2


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Basic Information Top
Gene Symbol:GRM2 ( GLUR2,GPRC1B,MGLUR2,mGlu2 )
Gene Full Name: glutamate receptor, metabotropic 2
Band: 3p21.2
Quick LinksEntrez ID:2912; OMIM: 604099; Uniprot ID:GRM2_HUMAN; ENSEMBL ID: ENSG00000164082; HGNC ID: 4594
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
203N-linked (GlcNAc...) (Potential).
286N-linked (GlcNAc...) (Potential).
338N-linked (GlcNAc...) (Potential).
402N-linked (GlcNAc...) (Potential).
547N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000839
  • Location:chr3 51718003-51727662
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 51715775 51716543 768 1845
NRSF JurkatGSE13047 51715596 51716063 467 2174
NRSF-mono JurkatQuESTdata 51715810 51716687 877 1755
NRSF-poly JurkatQuESTdata 51715596 51716339 743 2036
Rb shRbQuiescentGSE19898 51716090 51716265 175 1826
hScc1 BcellGSE12603 51715746 51716689 943 1786
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 51728263 51728537 274 738
CTCF CD4SISSRdata 51728263 51728537 274 738
CTCF HelaGSE12889 51728268 51728500 232 722
CTCF G2GSE9613 51727843 51729339 1496 929
ER E2-MCF7GSE14664 51739204 51739261 57 11570
ER Fulvestrant-MCF7GSE14664 51739208 51739261 53 11572
Oct1 H2O2-HelaGSE14283 51742535 51742572 37 14891
Oct1 HelaGSE14283 51739176 51739265 89 11558
Oct1 HelaGSE14283 51742537 51742572 35 14892
TFAP2C MCF7GSE21234 51728125 51728553 428 677
hScc1 BcellGSE12603 51728210 51729025 815 955
hScc1 G2GSE9613 51727843 51729061 1218 790
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 51717961 51718365 404 0
CTCF G2GSE9613 51719653 51720236 583 0
CTCF G2GSE9613 51720918 51721317 399 0
CTCF G2GSE9613 51725701 51726125 424 0
CTCF G2GSE9613 51726426 51726753 327 0
hScc1 BcellGSE12603 51726426 51726753 327 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018