AutismKB 2.0

Annotation Detail for UHRF1


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Basic Information Top
Gene Symbol:UHRF1 ( FLJ21925,ICBP90,MGC138707,Np95,RNF106,hNP95 )
Gene Full Name: ubiquitin-like with PHD and ring finger domains 1
Band: 19p13.3
Quick LinksEntrez ID:29128; OMIM: 607990; Uniprot ID:UHRF1_HUMAN; ENSEMBL ID: ENSG00000034063; HGNC ID: 12556
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
76Phosphoserine.
91Phosphoserine.
287Phosphoserine.
298Phosphoserine; by PKA; in vitro.
399N6-acetyllysine.
546N6-acetyllysine.
639Phosphoserine.
707Phosphoserine.
Location(AA) Modifications Resource
287Phosphoserine.Swiss-Prot 53.0
298Phosphoserine; by PKA; in vitro.Swiss-Prot 53.0
639Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
66N-linkedHMM predict
88Phosphoserine(CK1)HMM predict
91Phosphoserine(CK2)HMM predict
91Phosphoserine(CK1)HMM predict
104Phosphoserine(ATM)HMM predict
107Phosphoserine(CK1)HMM predict
108Phosphoserine(CK1)HMM predict
135Phosphotyrosine(INSR)HMM predict
160Phosphothreonine(PKC)HMM predict
172Phosphoserine(CK1)HMM predict
249Phosphothreonine(PKA)HMM predict
298Phosphoserine(IKK)HMM predict
298Phosphoserine(PKA)HMM predict
354Phosphoserine(CK1)HMM predict
380Phosphoserine(PKG)HMM predict
391Phosphoserine(CK1)HMM predict
418Phosphotyrosine(SRC)HMM predict
547Phosphotyrosine(INSR)HMM predict
555Phosphotyrosine(INSR)HMM predict
559Phosphotyrosine(Syk)HMM predict
611Phosphotyrosine(Syk)HMM predict
625Phosphoserine(CK1)HMM predict
625Phosphoserine(CK2)HMM predict
657O-linkedHMM predict
661PhosphoserineHMM predict
661Phosphoserine(CDC2)HMM predict
665Phosphothreonine(PKC)HMM predict
666Phosphoserine(PKG)HMM predict
666Phosphoserine(PKA)HMM predict
736Phosphothreonine(PKA)HMM predict
791AsparagineHMM predict
793ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001048201
  • Location:chr19 4860509-4913163
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 4860708 4861335 627 0
p130 SenescentGSE19898 4860906 4861205 299 0
p130 shRbQuiescentGSE19898 4860863 4861206 343 0
Validated miRNA targets Top
No data
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
355 Unknown MicroArray miR-124 UHRF1 n_a 15685193
908 Unknown pSILAC let-7b UHRF1 down 50-25% 18668040
1210 Unknown pSILAC miR-1 UHRF1 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000034063 G1-to-S transition n_a n_a "epithelium, lymphocyte, muscle cell" "tumour, malignant tumour, carcinoma, leukaemia"
ENSG00000034063 n_a n_a n_a "epithelium, lymphocyte, muscle cell" "tumour, malignant tumour, carcinoma, leukaemia"
ENSG00000034063 n_a n_a n_a "epithelium, lymphocyte, muscle cell" "tumour, malignant tumour, carcinoma, leukaemia"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
12542 mRNA UHRF1 chr19 4860512 4913160 155 mRNA C19orf31 chr19 4858741 4861019Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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