Annotation Detail for GRM6

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Basic Information Top

Gene Symbol:	GRM6 ( CSNB1B,DKFZp686H1993,GPRC1F,MGLUR6,mGlu6 )
Gene Full Name:	glutamate receptor, metabotropic 6
Band:	5q35.3
Quick Links	Entrez ID:2916; OMIM: 604096; Uniprot ID:GRM6_HUMAN; ENSEMBL ID: ENSG00000113262; HGNC ID: 4598
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:4 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
296	N-linked (GlcNAc...) (Potential).
451	N-linked (GlcNAc...) (Potential).
479	N-linked (GlcNAc...) (Potential).
567	N-linked (GlcNAc...) (Potential).

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_000843
Location:chr5 178337935-178354729
strand:-

Upstream the gene:3 results
Downstream the gene:0 results
Inside the gene:7 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	178356395	178356787	392	1862
CTCF	G2	GSE9613	178361109	178361410	301	6530
hScc1	Bcell	GSE12603	178358065	178358404	339	3505

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	178343783	178344389	606	0
CTCF	G2	GSE9613	178345672	178346655	983	0
CTCF	G2	GSE9613	178350949	178351929	980	0
CTCF	G2	GSE9613	178353181	178353844	663	0
CTCF	G2	GSE9613	178354096	178355017	921	0
hScc1	Bcell	GSE12603	178353005	178353279	274	0
hScc1	Bcell	GSE12603	178354060	178354613	553	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
21964	EST		chr5	178328996	178349723	11786	mRNA	GRM6	chr5	178337937	178354730	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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