AutismKB 2.0

Annotation Detail for BRF1


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Basic Information Top
Gene Symbol:BRF1 ( BRF,FLJ42674,FLJ43034,GTF3B,MGC105048,TAF3B2,TAF3C,TAFIII90,TF3B90,TFIIIB90,hBRF )
Gene Full Name: BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)
Band: 14q32.33
Quick LinksEntrez ID:2972; OMIM: 604902; Uniprot ID:TF3B_HUMAN; ENSEMBL ID: ENSG00000185024; HGNC ID: 11551
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
365Phosphothreonine.
433Phosphoserine.
450Phosphoserine.
553Phosphoserine.
Location(AA) Modifications Resource
433Phosphoserine (By similarity).Swiss-Prot 53.0
553Phosphoserine.Swiss-Prot 53.0
553PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
85Phosphothreonine(PKC)HMM predict
123Phosphothreonine(PKC)HMM predict
145Phosphothreonine(PKA)HMM predict
245Phosphothreonine(PKC)HMM predict
270Phosphothreonine(MAPK)HMM predict
365Phosphothreonine(CK2)HMM predict
382Phosphotyrosine(EGFR)HMM predict
393O-linkedHMM predict
393O-linkedHMM predict
398Phosphoserine(ATM)HMM predict
433Phosphoserine(ATM)HMM predict
442Phosphoserine(CK2)HMM predict
450Phosphoserine(CK2)HMM predict
463N-linkedHMM predict
571O-linkedHMM predict
575Phosphothreonine(MAPK)HMM predict
575Phosphothreonine(PKA)HMM predict
575Phosphothreonine(CDK)HMM predict
580Phosphoserine(IKK)HMM predict
614Phosphoserine(CDK)HMM predict
614Phosphoserine(MAPK)HMM predict
667Phosphotyrosine(INSR)HMM predict
669S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001519
  • Location:chr14 104746670-104838373
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 104841386 104841546 160 3093
Nanog ESGSE20650 104844392 104844848 456 6247
Oct4 ESGSE20650 104844503 104844834 331 6295
PHF8 HeLaGSE20725 104837636 104839155 1519 22
hScc1 BcellGSE12603 104841386 104841546 160 3093
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 104819288 104819589 301 0
CTCF CD4SISSRdata 104819288 104819589 301 0
CTCF G2GSE9613 104799034 104799538 504 0
CTCF G2GSE9613 104805372 104805780 408 0
CTCF G2GSE9613 104806360 104806738 378 0
CTCF G2GSE9613 104807065 104807296 231 0
CTCF G2GSE9613 104808204 104808432 228 0
CTCF G2GSE9613 104808846 104809772 926 0
CTCF G2GSE9613 104813305 104814970 1665 0
CTCF G2GSE9613 104818178 104819471 1293 0
CTCF G2GSE9613 104827873 104828363 490 0
CTCF G2GSE9613 104829952 104831043 1091 0
CTCF G2GSE9613 104831619 104831751 132 0
CTCF G2GSE9613 104837440 104838366 926 0
H3ac HepG2E 104813305 104814274 969 0
KLF4 hESGSE17917 104805034 104805259 225 0
Oct1 H2O2-HelaGSE14283 104792058 104792101 43 0
Oct1 H2O2-HelaGSE14283 104807313 104807341 28 0
PHF8 Hs68minusFBSGSE20725 104837679 104838982 1303 0
RARA MCF7GSE15244 104813305 104814907 1602 0
RARA MCF7GSE15244 104817897 104819332 1435 0
RARG MCF7GSE15244 104817897 104819191 1294 0
RARG MCF7GSE15244 104821065 104822039 974 0
TFAP2C MCF7GSE21234 104805337 104805783 446 0
TFAP2C MCF7GSE21234 104830609 104831206 597 0
TFAP2C MCF7GSE21234 104837140 104837625 485 0
hScc1 BcellGSE12603 104785512 104786148 636 0
hScc1 BcellGSE12603 104800686 104800999 313 0
hScc1 BcellGSE12603 104807065 104807334 269 0
hScc1 BcellGSE12603 104809237 104809622 385 0
hScc1 BcellGSE12603 104817897 104819259 1362 0
hScc1 BcellGSE12603 104828021 104828503 482 0
hScc1 BcellGSE12603 104830431 104830900 469 0
hScc1 BcellGSE12603 104831652 104831968 316 0
hScc1 BcellGSE12603 104837404 104838241 837 0
hScc1 CdLSGSE12603 104785794 104786148 354 0
hScc1 CdLSGSE12603 104819158 104819530 372 0
hScc1 CdLSGSE12603 104837472 104838031 559 0
p130 QuiescentGSE19898 104837774 104837929 155 0
p130 shRbQuiescentGSE19898 104831444 104831856 412 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8455 mRNA BTBD6 chr14 104786052 104788475 136 mRNA BRF1 chr14 104746670 104786786Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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