AutismKB 2.0

Annotation Detail for GTF3C1


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Basic Information Top
Gene Symbol:GTF3C1 ( DKFZp686A111,TFIIIC,TFIIIC220,TFIIICalpha )
Gene Full Name: general transcription factor IIIC, polypeptide 1, alpha 220kDa
Band: 16p12.1
Quick LinksEntrez ID:2975; OMIM: 603246; Uniprot ID:TF3C1_HUMAN; ENSEMBL ID: ENSG00000077235; HGNC ID: 4664
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
739Phosphoserine.
751Phosphoserine.
774Phosphothreonine.
1062Phosphoserine.
1064Phosphothreonine.
1068Phosphoserine.
1611Phosphoserine.
1632Phosphoserine.
1653Phosphoserine.
1856Phosphoserine.
1865Phosphoserine.
1868Phosphoserine.
1969Phosphoserine.
Location(AA) Modifications Resource
739Phosphoserine.Swiss-Prot 53.0
739PhosphoserinePhospho.ELM 6.0
1062Phosphoserine.Swiss-Prot 53.0
1062PhosphoserinePhospho.ELM 6.0
1068PhosphoserinePhospho.ELM 6.0
1068Phosphoserine.Swiss-Prot 53.0
1653Phosphoserine.Swiss-Prot 53.0
1653PhosphoserinePhospho.ELM 6.0
1865Phosphoserine.Swiss-Prot 53.0
1865PhosphoserinePhospho.ELM 6.0
1868Phosphoserine.Swiss-Prot 53.0
1868PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
30Phosphothreonine(PKC)HMM predict
75Phosphotyrosine(Syk)HMM predict
122N-linkedHMM predict
125N-linkedHMM predict
253Phosphoserine(CK1)HMM predict
317S-palmitoylHMM predict
326Phosphothreonine(PKA)HMM predict
354Phosphoserine(CK1)HMM predict
381Phosphothreonine(PKC)HMM predict
381Phosphothreonine(PKA)HMM predict
385Phosphoserine(ATM)HMM predict
385Phosphoserine(CK2)HMM predict
425Phosphothreonine(PKC)HMM predict
478Phosphoserine(ATM)HMM predict
480Phosphoserine(CK1)HMM predict
480Phosphoserine(CK2)HMM predict
485Phosphoserine(CK1)HMM predict
486Phosphoserine(CK1)HMM predict
487Phosphoserine(CK1)HMM predict
490MethylarginineHMM predict
514Phosphothreonine(CDK)HMM predict
514Phosphothreonine(CDC2)HMM predict
546Phosphoserine(IKK)HMM predict
552Phosphoserine(IKK)HMM predict
552Phosphoserine(CK1)HMM predict
558Phosphoserine(IKK)HMM predict
558Phosphoserine(CK1)HMM predict
563N-linkedHMM predict
593Phosphoserine(CK2)HMM predict
594Phosphoserine(CDC2)HMM predict
595Phosphoserine(CK1)HMM predict
598Phosphothreonine(PKC)HMM predict
603Phosphoserine(PKB)HMM predict
654S-palmitoylHMM predict
655S-palmitoylHMM predict
665N-linkedHMM predict
667Phosphoserine(CK1)HMM predict
716N-linkedHMM predict
721N-linkedHMM predict
725Phosphothreonine(PKC)HMM predict
726Phosphoserine(PKG)HMM predict
739Phosphoserine(ATM)HMM predict
746O-linkedHMM predict
751Phosphoserine(ATM)HMM predict
759Phosphoserine(CK1)HMM predict
767Phosphoserine(PKG)HMM predict
819Phosphothreonine(PKC)HMM predict
844Phosphoserine(PKA)HMM predict
846O-linkedHMM predict
858Phosphoserine(CK1)HMM predict
861Phosphoserine(IKK)HMM predict
1061N-linkedHMM predict
1062Phosphoserine(PKG)HMM predict
1068PhosphoserineHMM predict
1068Phosphoserine(CK2)HMM predict
1068Phosphoserine(CK2)HMM predict
1202Phosphoserine(CK1)HMM predict
1264Phosphothreonine(PKA)HMM predict
1357Phosphotyrosine(INSR)HMM predict
1357Phosphotyrosine(Syk)HMM predict
1440Phosphoserine(ATM)HMM predict
1442Phosphoserine(ATM)HMM predict
1483N-linkedHMM predict
1732Phosphoserine(ATM)HMM predict
1734Phosphotyrosine(INSR)HMM predict
1767Phosphoserine(PKG)HMM predict
1842Phosphoserine(IKK)HMM predict
1845Phosphoserine(CK1)HMM predict
1845Phosphoserine(ATM)HMM predict
1845Phosphoserine(IKK)HMM predict
1854O-linkedHMM predict
1856Phosphoserine(CDC2)HMM predict
1860Phosphothreonine(PKC)HMM predict
1865Phosphoserine(CAMK2)HMM predict
1865Phosphoserine(PKB)HMM predict
1865Phosphoserine(PKA)HMM predict
1865Phosphoserine(PKG)HMM predict
1865Phosphoserine(IKK)HMM predict
1881Phosphothreonine(CDC2)HMM predict
1891Phosphoserine(IKK)HMM predict
1911Phosphoserine(CDC2)HMM predict
1911O-linkedHMM predict
2059Phosphoserine(IKK)HMM predict
2074Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001520
  • Location:chr16 27379435-27468751
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
HIF1 NormHepG2 27468486 27469122 636 53
PHF8 HeLaGSE20725 27468086 27469493 1407 38
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 27375997 27376221 224 3327
CTCF CD4SISSRdata 27375997 27376221 224 3327
CTCF JurkatGSE12889 27375958 27376350 392 3282
CTCF G2GSE9613 27375981 27376229 248 3331
Oct1 H2O2-HelaGSE14283 27377759 27377790 31 1661
STAT1 IFNSISSRdata 27375875 27376217 342 3390
hScc1 BcellGSE12603 27375981 27376369 388 3261
hScc1 CdLSGSE12603 27375981 27376369 388 3261
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 27434793 27434948 155 0
CTCF CD4SISSRdata 27434793 27434948 155 0
CTCF G2GSE9613 27407608 27407847 239 0
CTCF G2GSE9613 27425577 27425791 214 0
CTCF G2GSE9613 27432814 27433266 452 0
CTCF G2GSE9613 27434860 27435444 584 0
CTCF G2GSE9613 27460531 27460704 173 0
CTCF G2GSE9613 27468426 27468780 354 0
Fos K562GSE19551 27465836 27466533 697 0
H3K4me2 HCT116GSE10453 27468004 27468331 327 0
H3K4me3 colorectalcancer 27468004 27468331 327 0
H3ac HepG2E 27468004 27468426 422 0
TAF HelaGSE8489 27440330 27440498 168 0
TFAP2C MCF7GSE21234 27422511 27422970 459 0
hScc1 BcellGSE12603 27449794 27450151 357 0
hScc1 BcellGSE12603 27468407 27468878 471 0
p130 SenescentGSE19898 27413652 27413889 237 0
p130 SenescentGSE19898 27453134 27453457 323 0
p63 keratinocytesGSE17611 27423936 27425094 1158 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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