AutismKB 2.0

Annotation Detail for BLNK


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Basic Information Top
Gene Symbol:BLNK ( AGM4,BASH,BLNK-S,LY57,MGC111051,SLP-65,SLP65 )
Gene Full Name: B-cell linker
Band: 10q24.1
Quick LinksEntrez ID:29760; OMIM: 604515; Uniprot ID:BLNK_HUMAN; ENSEMBL ID: ENSG00000095585; HGNC ID: 14211
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
72Phosphotyrosine.
84Phosphotyrosine.
96Phosphotyrosine.
178Phosphotyrosine.
189Phosphotyrosine.
Location(AA) Modifications Resource
72Phosphotyrosine.Swiss-Prot 53.0
72Phosphotyrosine (Syk)Phospho.ELM 6.0
84Phosphotyrosine.Swiss-Prot 53.0
84Phosphotyrosine (Syk)Phospho.ELM 6.0
96Phosphotyrosine.Swiss-Prot 53.0
96Phosphotyrosine (Syk)Phospho.ELM 6.0
178Phosphotyrosine.Swiss-Prot 53.0
178Phosphotyrosine (Syk)Phospho.ELM 6.0
189Phosphotyrosine.Swiss-Prot 53.0
189PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
70Phosphoserine(CK2)HMM predict
72Phosphotyrosine(INSR)HMM predict
72SulfotyrosineHMM predict
72Phosphotyrosine(Syk)HMM predict
79Phosphoserine(IKK)HMM predict
79Phosphoserine(CK1)HMM predict
84Phosphotyrosine(Syk)HMM predict
96Phosphotyrosine(EGFR)HMM predict
96Phosphotyrosine(Syk)HMM predict
122N-linkedHMM predict
125Phosphoserine(ATM)HMM predict
129Phosphoserine(IKK)HMM predict
129Phosphoserine(CDC2)HMM predict
135O-linkedHMM predict
141Phosphoserine(IKK)HMM predict
178SulfotyrosineHMM predict
178Phosphotyrosine(INSR)HMM predict
189Phosphotyrosine(EGFR)HMM predict
189SulfotyrosineHMM predict
189Phosphotyrosine(INSR)HMM predict
196O-linkedHMM predict
197Phosphoserine(ATM)HMM predict
197O-linkedHMM predict
197Phosphoserine(CDC2)HMM predict
207N-linkedHMM predict
210Phosphothreonine(PKA)HMM predict
213N-linkedHMM predict
215O-linkedHMM predict
216Phosphothreonine(CDK)HMM predict
216O-linkedHMM predict
219O-linkedHMM predict
219Phosphoserine(CDK)HMM predict
219Phosphoserine(IKK)HMM predict
219Phosphoserine(CDC2)HMM predict
225O-linkedHMM predict
234Phosphothreonine(PKC)HMM predict
236Phosphoserine(CDC2)HMM predict
236O-linkedHMM predict
236Phosphoserine(CDK)HMM predict
243O-linkedHMM predict
243Phosphoserine(CDC2)HMM predict
243Phosphoserine(CDK)HMM predict
253Phosphothreonine(PKA)HMM predict
254Phosphothreonine(CDK)HMM predict
254Phosphothreonine(MAPK)HMM predict
254PhosphothreonineHMM predict
266N-linkedHMM predict
284Phosphoserine(PKA)HMM predict
318N-linkedHMM predict
331N-linkedHMM predict
375Phosphoserine(PKB)HMM predict
394Phosphotyrosine(Abl)HMM predict
421Phosphoserine(CK2)HMM predict
441N-linkedHMM predict
442N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013314
  • Location:chr10 97941452-98021315
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARG MCF7GSE15244 98027183 98027396 213 5974
TFAP2C MCF7GSE21234 98037322 98037826 504 16259
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 97928959 97928991 32 12478
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 97979325 97979557 232 0
CTCF CD4SISSRdata 97979325 97979557 232 0
CTCF HelaGSE12889 97979356 97979637 281 0
Myc K562GSE19551 97979278 97979548 270 0
Nanog hESGSE18292 97971967 97972643 676 0
Oct1 H2O2-HelaGSE14283 97971186 97971227 41 0
Oct1 HelaGSE14283 97971185 97971226 41 0
Oct1 HelaGSE14283 98001969 98002003 34 0
Oct4 hESGSE17917 97979352 97979602 250 0
RARG MCF7GSE15244 97988159 97988609 450 0
RARG MCF7GSE15244 98017035 98017349 314 0
hScc1 BcellGSE12603 97979133 97979594 461 0
hScc1 CdLSGSE12603 97979099 97980109 1010 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3511 HTC chr10 97879818 97955034 117 mRNA BLNK chr10 97941446 98021316Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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