AutismKB 2.0

Annotation Detail for PACSIN3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PACSIN3 ( FLJ17861,SDPIII )
Gene Full Name: protein kinase C and casein kinase substrate in neurons 3
Band: 11p11.2
Quick LinksEntrez ID:29763; OMIM: 606513; Uniprot ID:PACN3_HUMAN; ENSEMBL ID: ENSG00000165912; HGNC ID: 8572
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
276Phosphoserine.
319Phosphoserine.
324Phosphothreonine.
327Phosphoserine.
344Phosphoserine.
354Phosphoserine.
383Phosphoserine.
Location(AA) Modifications Resource
276Phosphoserine.Swiss-Prot 53.0
276PhosphoserinePhospho.ELM 6.0
319Phosphoserine.Swiss-Prot 53.0
319PhosphoserinePhospho.ELM 6.0
354Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
25Phosphothreonine(PKC)HMM predict
74Phosphotyrosine(INSR)HMM predict
216Phosphotyrosine(INSR)HMM predict
256Phosphoserine(CK1)HMM predict
276Phosphoserine(CK2)HMM predict
276Phosphoserine(CK2)HMM predict
341Phosphoserine(CDC2)HMM predict
341O-linkedHMM predict
344Phosphoserine(ATM)HMM predict
344O-linkedHMM predict
344Phosphoserine(CDC2)HMM predict
354Phosphoserine(CK2)HMM predict
354Phosphoserine(CK1)HMM predict
358PhosphoserineHMM predict
364Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016223
  • Location:chr11 47155660-47164533
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 47167393 47167739 346 3033
H3ac HepG2E 47164880 47165347 467 580
H3ac HepG2E 47165935 47166571 636 1720
Oct1 H2O2-HelaGSE14283 47174337 47174366 29 9818
Oct1 HelaGSE14283 47174337 47174366 29 9818
RARA MCF7GSE15244 47166158 47166693 535 1892
RARA MCF7GSE15244 47167393 47167739 346 3033
RARA MCF7GSE15244 47172009 47172597 588 7770
RARA MCF7GSE15244 47172935 47173277 342 8573
RARG MCF7GSE15244 47167393 47167739 346 3033
RARG MCF7GSE15244 47172009 47172597 588 7770
STAT1 HeLaGSE12783 47171631 47173620 1989 8092
TFAP2C MCF7GSE21234 47171847 47172798 951 7789
USF1 HepG2E 47167393 47167739 346 3033
USF2 HepG2E 47167393 47167739 346 3033
hScc1 BcellGSE12603 47169499 47169765 266 5099
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 47155412 47155819 407 45
hScc1 BcellGSE12603 47155066 47155991 925 132
hScc1 CdLSGSE12603 47154742 47155991 1249 294
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 HeLaGSE20725 47162748 47165297 2549 0
Rb QuiescentGSE19898 47163804 47164008 204 0
Rb SenescentGSE19898 47163649 47163821 172 0
TFAP2C MCF7GSE21234 47163198 47164085 887 0
hScc1 BcellGSE12603 47164207 47164808 601 0
hScc1 CdLSGSE12603 47160349 47160747 398 0
hScc1 G2GSE9613 47155066 47156519 1453 0
hScc1 G2GSE9613 47163735 47164808 1073 0
p130 SenescentGSE19898 47163378 47163746 368 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018