AutismKB 2.0

Annotation Detail for ZDHHC8


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Basic Information Top
Gene Symbol:ZDHHC8 ( DHHC8,ZDHHCL1,ZNF378 )
Gene Full Name: zinc finger, DHHC-type containing 8
Band: 22q11.21
Quick LinksEntrez ID:29801; OMIM: 608784; Uniprot ID:ZDHC8_HUMAN; ENSEMBL ID: ENSG00000099904; HGNC ID: 18474
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
337Phosphoserine (By similarity).
438Phosphoserine.
675Phosphoserine (By similarity).
741Phosphoserine.
743Phosphoserine.
Location(AA) Modifications Resource
337Phosphoserine (By similarity).Swiss-Prot 53.0
675Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
19O-linkedHMM predict
44Phosphoserine(CDC2)HMM predict
44Phosphoserine(PKG)HMM predict
222Phosphothreonine(PKC)HMM predict
332Phosphothreonine(MAPK)HMM predict
343Phosphoserine(CK1)HMM predict
347O-linkedHMM predict
348O-linkedHMM predict
348Phosphoserine(CDC2)HMM predict
348Phosphoserine(CDK)HMM predict
405Phosphotyrosine(INSR)HMM predict
417Phosphoserine(MAPK)HMM predict
417Phosphoserine(ATM)HMM predict
417O-linkedHMM predict
459Phosphothreonine(MAPK)HMM predict
459Phosphothreonine(CDK)HMM predict
459Phosphothreonine(CDC2)HMM predict
474N-linkedHMM predict
487Phosphoserine(CDC2)HMM predict
508Phosphotyrosine(Syk)HMM predict
567Phosphoserine(ATM)HMM predict
579Phosphotyrosine(INSR)HMM predict
579Phosphotyrosine(Syk)HMM predict
586Phosphoserine(CK1)HMM predict
632Phosphoserine(CK1)HMM predict
634Phosphoserine(CK1)HMM predict
642Phosphoserine(CK1)HMM predict
642O-linkedHMM predict
643Phosphoserine(PKA)HMM predict
643Phosphoserine(IKK)HMM predict
643Phosphoserine(CK1)HMM predict
661O-linkedHMM predict
664O-linkedHMM predict
675Phosphoserine(MAPK)HMM predict
675Phosphoserine(CDC2)HMM predict
675O-linkedHMM predict
679Phosphothreonine(CDC2)HMM predict
684O-linkedHMM predict
716Phosphothreonine(MAPK)HMM predict
716Phosphothreonine(CDK)HMM predict
741O-linkedHMM predict
743O-linkedHMM predict
743Phosphoserine(CDC2)HMM predict
748Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013373
  • Location:chr22 18499364-18513957
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 18496856 18497217 361 2328
PHF8 HeLaGSE20725 18497850 18499186 1336 847
hScc1 CdLSGSE12603 18498646 18499072 426 506
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 18524574 18524795 221 10727
CTCF CD4SISSRdata 18524574 18524795 221 10727
CTCF HelaGSE12889 18524456 18524847 391 10694
CTCF JurkatGSE12889 18524556 18524815 259 10728
CTCF G2GSE9613 18524413 18525088 675 10793
CTCF G2GSE9613 18526607 18527245 638 12969
Myc K562GSE19551 18524317 18524885 568 10644
RUNX JurkatGSE17954 18530724 18530816 92 16813
Rb shRbQuiescentGSE19898 18520075 18520219 144 6190
hScc1 BcellGSE12603 18514437 18514884 447 703
hScc1 BcellGSE12603 18524413 18525442 1029 10970
hScc1 CdLSGSE12603 18524389 18525195 806 10835
hScc1 G2GSE9613 18524389 18525125 736 10800
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 18501549 18502055 506 0
hScc1 BcellGSE12603 18499447 18499598 151 0
hScc1 BcellGSE12603 18508947 18509309 362 0
hScc1 BcellGSE12603 18510525 18512021 1496 0
hScc1 BcellGSE12603 18512990 18513638 648 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17153 mRNA ZDHHC8 chr22 18501561 18508527 33 EST chr22 18508494 18508888Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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