AutismKB 2.0

Annotation Detail for ANAPC2


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Basic Information Top
Gene Symbol:ANAPC2 ( APC2,RP11-350O14.5 )
Gene Full Name: anaphase promoting complex subunit 2
Band: 9q34.3
Quick LinksEntrez ID:29882; OMIM: 606946; Uniprot ID:ANC2_HUMAN; ENSEMBL ID: ENSG00000176248; HGNC ID: 19989
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
218Phosphoserine.
314Phosphoserine.
470Phosphoserine.
534Phosphoserine.
810Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
218Phosphoserine.Swiss-Prot 53.0
314Phosphoserine.Swiss-Prot 53.0
314PhosphoserinePhospho.ELM 6.0
534Phosphoserine.Swiss-Prot 53.0
534PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
41O-linkedHMM predict
86N-linkedHMM predict
314O-linkedHMM predict
314Phosphoserine(MAPK)HMM predict
320Phosphothreonine(PKC)HMM predict
457Phosphoserine(CK1)HMM predict
470Phosphoserine(CAMK2)HMM predict
470PhosphoserineHMM predict
470Phosphoserine(CK2)HMM predict
474Phosphoserine(ATM)HMM predict
492Phosphoserine(CDC2)HMM predict
493Phosphoserine(CDC2)HMM predict
534Phosphoserine(CDC2)HMM predict
697Phosphoserine(PKA)HMM predict
697Phosphoserine(PKA)HMM predict
736Phosphoserine(CK1)HMM predict
742Phosphoserine(ATM)HMM predict
769Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013366
  • Location:chr9 139189056-139202877
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAFII hESGSE17917 139202565 139203224 659 17
VDR GM10861-stimGSE22484 139202252 139203527 1275 12
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 139187057 139188125 1068 1466
TFAP2C MCF7GSE21234 139187225 139188135 910 1377
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 139190956 139191129 173 0
CTCF CD4SISSRdata 139190956 139191129 173 0
H3K4me3 colorectalcancer 139201032 139201521 489 0
PHF8 293TGSE20725 139202225 139203401 1176 0
PHF8 Hs68plusFBSGSE20725 139201933 139203717 1784 0
hScc1 BcellGSE12603 139189422 139189969 547 0
hScc1 BcellGSE12603 139192882 139194036 1154 0
hScc1 BcellGSE12603 139195659 139196267 608 0
hScc1 BcellGSE12603 139196806 139197087 281 0
hScc1 BcellGSE12603 139198144 139199059 915 0
hScc1 BcellGSE12603 139199982 139200398 416 0
hScc1 G2GSE9613 139198387 139199636 1249 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018