AutismKB 2.0

Annotation Detail for CPSF1


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Basic Information Top
Gene Symbol:CPSF1 ( CPSF160,HSU37012,P/cl.18 )
Gene Full Name: cleavage and polyadenylation specific factor 1, 160kDa
Band: 8q24.3
Quick LinksEntrez ID:29894; OMIM: 606027; Uniprot ID:CPSF1_HUMAN; ENSEMBL ID: ENSG00000071894; HGNC ID: 2324
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
739Phosphothreonine.
908Nuclear localization signal (Potential).
Location(AA) Modifications Resource
739Phosphothreonine.Swiss-Prot 53.0
739PhosphothreoninePhospho.ELM 6.0
766PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
24N-linkedHMM predict
25N-linkedHMM predict
29N-linkedHMM predict
104Phosphoserine(PKG)HMM predict
168Phosphoserine(PKG)HMM predict
224N-linkedHMM predict
246N-linkedHMM predict
290N-linkedHMM predict
308O-linkedHMM predict
562PhosphothreonineHMM predict
756Phosphoserine(CDC2)HMM predict
765Phosphoserine(CDK)HMM predict
765Phosphoserine(PKG)HMM predict
766Phosphoserine(PKG)HMM predict
766Phosphoserine(ATM)HMM predict
766Phosphoserine(PKA)HMM predict
791N-linkedHMM predict
946S-palmitoylHMM predict
999Phosphoserine(PKG)HMM predict
1034Phosphotyrosine(Syk)HMM predict
1034Phosphotyrosine(SRC)HMM predict
1040O-linkedHMM predict
1042Phosphothreonine(MAPK)HMM predict
1042O-linkedHMM predict
1066Phosphotyrosine(INSR)HMM predict
1066SulfotyrosineHMM predict
1110Phosphoserine(CK1)HMM predict
1184Phosphoserine(CAMK2)HMM predict
1356Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013291
  • Location:chr8 145589254-145605540
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 145605492 145605722 230 67
CTCF CD4SISSRdata 145605492 145605722 230 67
Myc K562GSE19551 145605253 145606000 747 86
PHF8 HeLaGSE20725 145605003 145606258 1255 90
Rb shRbQuiescentGSE19898 145605449 145605656 207 12
hScc1 BcellGSE12603 145605225 145606140 915 142
hScc1 CdLSGSE12603 145605225 145605912 687 28
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 145604608 145606419 1811 0
Gata1 K562GSE18868 145597999 145598609 610 0
Gata2 K562GSE18868 145597854 145598562 708 0
H3K4me3 colorectalcancer 145604472 145604836 364 0
H3ac HepG2E 145604231 145604953 722 0
NRSF pAbJurkat 145589622 145591028 1406 0
NRSF pAbJurkat 145593220 145594403 1183 0
NRSF pAbJurkat 145596296 145597445 1149 0
NRSF pAbJurkat 145597686 145598121 435 0
Rb QuiescentGSE19898 145605453 145605592 139 0
Rb SenescentGSE19898 145604963 145605983 1020 0
VDR GM10855-stimGSE22484 145604802 145606241 1439 0
VDR GM10861-UnstimGSE22484 145604452 145606213 1761 0
VDR GM10861-stimGSE22484 145604841 145606193 1352 0
p130 QuiescentGSE19898 145605166 145605416 250 0
p130 SenescentGSE19898 145605207 145605751 544 0
p130 shRbSenescentGSE19898 145605249 145605523 274 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018