AutismKB 2.0

Annotation Detail for SEC61A1


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Basic Information Top
Gene Symbol:SEC61A1 ( HSEC61,SEC61,SEC61A )
Gene Full Name: Sec61 alpha 1 subunit (S. cerevisiae)
Band: 3q21.3
Quick LinksEntrez ID:29927; OMIM: 609213; Uniprot ID:S61A1_HUMAN; ENSEMBL ID: ENSG00000058262; HGNC ID: 18276
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
45S-palmitoylHMM predict
46S-palmitoylHMM predict
56Phosphoserine(ATM)HMM predict
75Phosphothreonine(PKC)HMM predict
105Phosphothreonine(MAPK)HMM predict
197Phosphoserine(CDC2)HMM predict
199O-linkedHMM predict
328O-linkedHMM predict
346Phosphoserine(ATM)HMM predict
416Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013336
  • Location:chr3 129253901-129273214
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 129252890 129254776 1886 69
FOXA1 MCF7GSE15244 129252986 129253548 562 635
H3K4me2 HCT116GSE10453 129252695 129253368 673 870
H3K4me3 colorectalcancer 129252804 129253512 708 744
H3ac HepG2E 129252583 129253821 1238 700
PHF8 293TGSE20725 129253128 129254589 1461 43
p130 SenescentGSE19898 129252798 129253830 1032 588
p130 shRbQuiescentGSE19898 129253009 129253680 671 557
p63 keratinocytesGSE17611 129241416 129242206 790 12091
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 129277060 129277416 356 4024
CTCF CD4SISSRdata 129277060 129277416 356 4024
CTCF G2GSE9613 129274074 129274372 298 1009
Rb SenescentGSE19898 129277179 129277459 280 4105
TFAP2C MCF7GSE21234 129273861 129274547 686 990
hScc1 BcellGSE12603 129276943 129277730 787 4122
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 129269603 129269864 261 0
CTCF CD4SISSRdata 129269603 129269864 261 0
CTCF G2GSE9613 129253619 129254279 660 0
CTCF G2GSE9613 129269269 129270261 992 0
CTCF G2GSE9613 129272199 129273552 1353 0
ER E2-MCF7GSE14664 129264668 129264701 33 0
FOXA1 MCF7GSE15244 129254182 129254742 560 0
H3K4me3 colorectalcancer 129254279 129256142 1863 0
H3ac HepG2E 129254182 129256349 2167 0
Myc K562GSE19551 129269624 129269983 359 0
PHF8 HeLaGSE20725 129253114 129254702 1588 0
TAF k562GSE8489 129254253 129255855 1602 0
hScc1 BcellGSE12603 129253619 129254279 660 0
hScc1 BcellGSE12603 129268273 129268520 247 0
hScc1 G2GSE9613 129253760 129254253 493 0
hScc1 G2GSE9613 129269557 129270199 642 0
hScc1 G2GSE9613 129272345 129272924 579 0
p63 keratinocytesGSE17611 129262349 129263245 896 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
18644 mRNA SEC61A1 chr3 129253909 129273223 718 EST chr3 129272202 129273220Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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