AutismKB 2.0

Annotation Detail for MDFIC


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Basic Information Top
Gene Symbol:MDFIC ( HIC )
Gene Full Name: MyoD family inhibitor domain containing
Band: 7q31.1-q31.2
Quick LinksEntrez ID:29969; OMIM: NA; Uniprot ID:MDFIC_HUMAN; ENSEMBL ID: ENSG00000135272; HGNC ID: 28870
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
140Phosphoserine.
143Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
15O-linkedHMM predict
15O-linkedHMM predict
85Phosphoserine(MAPK)HMM predict
85Phosphoserine(IKK)HMM predict
87O-linkedHMM predict
88O-linkedHMM predict
111Phosphoserine(IKK)HMM predict
233Phosphoserine(PKG)HMM predict
237Phosphoserine(ATM)HMM predict
249Phosphoserine(ATM)HMM predict
249Phosphoserine(CK1)HMM predict
249Phosphoserine(CK2)HMM predict
270Phosphoserine(CK2)HMM predict
345CysteineHMM predict
349S-palmitoylHMM predict
350GlycineHMM predict
351IsoleucineHMM predict
352S-farnesylHMM predict
352CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_199072
  • Location:chr7 114349444-114446498
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM12878GSE19485 114342821 114346025 3204 5022
NFkBII GM15510GSE19485 114343249 114345366 2117 5137
NFkBII GM18505GSE19485 114343146 114345292 2146 5226
RNAII Tamoxifen-MCF7GSE14664 114331481 114331566 85 17921
VDR GM10855-stimGSE22484 114342728 114346476 3748 4843
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 114451951 114452198 247 5576
CTCF CD4SISSRdata 114451951 114452198 247 5576
Oct1 HelaGSE14283 114454108 114454149 41 7630
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 114442801 114443580 779 0
CTCF G2GSE9613 114349267 114350358 1091 0
Nanog ESGSE20650 114357245 114357835 590 0
Nanog hESGSE18292 114357213 114357775 562 0
Oct1 HelaGSE14283 114397086 114397116 30 0
P300 T30-glioblastomaGSE21026 114442705 114443658 953 0
Rb QuiescentGSE19898 114350289 114350805 516 0
Rb SenescentGSE19898 114350421 114350874 453 0
TFAP2C MCF7GSE21234 114431344 114431759 415 0
hScc1 BcellGSE12603 114349309 114350468 1159 0
hScc1 CdLSGSE12603 114356801 114357239 438 0
hScc1 CdLSGSE12603 114358657 114359323 666 0
hScc1 CdLSGSE12603 114366991 114367244 253 0
hScc1 G2GSE9613 114349208 114350211 1003 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018