AutismKB 2.0

Annotation Detail for TNPO2


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Basic Information Top
Gene Symbol:TNPO2 ( FLJ12155,IPO3,KPNB2B,TRN2 )
Gene Full Name: transportin 2
Band: 19p13.13
Quick LinksEntrez ID:30000; OMIM: 603002; Uniprot ID:TNPO2_HUMAN; ENSEMBL ID: ENSG00000105576; HGNC ID: 19998
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
862N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
20Phosphoserine(ATM)HMM predict
57Phosphoserine(CAMK2)HMM predict
64Phosphoserine(CK1)HMM predict
78Phosphotyrosine(EGFR)HMM predict
344Phosphothreonine(PKA)HMM predict
344Phosphothreonine(PKC)HMM predict
368Phosphoserine(CK2)HMM predict
548Phosphoserine(ATM)HMM predict
630Phosphotyrosine(SRC)HMM predict
630Phosphotyrosine(Syk)HMM predict
724N-linkedHMM predict
743Phosphotyrosine(Abl)HMM predict
760Phosphothreonine(MAPK)HMM predict
773Phosphoserine(CAMK2)HMM predict
775O-linkedHMM predict
787Phosphotyrosine(INSR)HMM predict
787Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013433
  • Location:chr19 12671016-12694077
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 12694114 12696338 2224 1149
Fos K562GSE19551 12694213 12694939 726 499
H3K4me3 colorectalcancer 12695000 12695930 930 1388
H3ac HepG2E 12694613 12696242 1629 1350
LIN9 SGSE7516 12693422 12694756 1334 12
PHF8 293TGSE20725 12693430 12695105 1675 190
TAF HelaGSE8489 12694724 12695930 1206 1250
TAF k562GSE8489 12694687 12695930 1243 1231
USF1 HepG2E 12694226 12696242 2016 1157
USF2 HepG2E 12694302 12696242 1940 1195
p130 QuiescentGSE19898 12694420 12694759 339 512
p130 QuiescentGSE19898 12694782 12694932 150 780
p130 SenescentGSE19898 12694240 12695061 821 573
p130 shRbQuiescentGSE19898 12694335 12694848 513 514
p130 shRbSenescentGSE19898 12694244 12694963 719 526
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 12688703 12689018 315 0
CTCF CD4SISSRdata 12688703 12689018 315 0
CTCF G2GSE9613 12673615 12673956 341 0
Fos K562GSE19551 12674675 12675296 621 0
H3ac HepG2E 12693198 12693939 741 0
KLF4 hESGSE17917 12677873 12678040 167 0
Oct1 H2O2-HelaGSE14283 12672200 12672229 29 0
USF1 HepG2E 12693236 12693904 668 0
hScc1 BcellGSE12603 12672617 12673709 1092 0
hScc1 BcellGSE12603 12691077 12691302 225 0
hScc1 BcellGSE12603 12692786 12694226 1440 0
p130 shRbQuiescentGSE19898 12693295 12694065 770 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018