AutismKB 2.0

Annotation Detail for ANXA1


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Basic Information Top
Gene Symbol:ANXA1 ( ANX1,LPC1 )
Gene Full Name: annexin A1
Band: 9q21.13
Quick LinksEntrez ID:301; OMIM: 151690; Uniprot ID:ANXA1_HUMAN; ENSEMBL ID: ENSG00000135046; HGNC ID: 533
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
5Phosphoserine; by TRPM7.
21Phosphotyrosine; by EGFR.
24Phosphothreonine.
27Phosphoserine; by PKC.
39Phosphotyrosine.
161N6-acetyllysine.
207Phosphotyrosine.
239N6-acetyllysine.
250N6-acetyllysine.
281N6-acetyllysine.
312N6-acetyllysine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
4PhosphoserinePhospho.ELM 6.0
5Phosphoserine (by TRPM7).Swiss-Prot 53.0
19Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?).Swiss-Prot 53.0
20Phosphotyrosine (Abl;Src;EGFR)Phospho.ELM 6.0
21Phosphotyrosine (by EGFR).Swiss-Prot 53.0
23Phosphothreonine (PKC
24Phosphothreonine.Swiss-Prot 53.0
26Phosphoserine (PKC alpha;PK)Phospho.ELM 6.0
27Phosphoserine (by PKC).Swiss-Prot 53.0
27Phosphoserine (PKC
207Phosphotyrosine.Swiss-Prot 53.0
215Phosphothreonine (PKA
Location(AA) Modification Resource
21Phosphotyrosine(Jak)HMM predict
21Phosphotyrosine(Abl)HMM predict
21Phosphotyrosine(SRC)HMM predict
21Phosphotyrosine(EGFR)HMM predict
24Phosphothreonine(PKC)HMM predict
34O-linkedHMM predict
37Phosphoserine(CDC2)HMM predict
41O-linkedHMM predict
170Phosphoserine(CK1)HMM predict
216Phosphothreonine(PKA)HMM predict
226Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000700
  • Location:chr9 74956600-74975126
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 74942005 74942472 467 14362
Fos K562GSE19551 74948629 74949061 432 7756
Fos K562GSE19551 74954106 74954650 544 2223
P300 T30-glioblastomaGSE21026 74948432 74949249 817 7760
PolII HeLaGSE12783 74936221 74938186 1965 19397
STAT1 HeLaGSE12783 74936625 74937675 1050 19451
TFAP2C MCF7GSE21234 74948701 74948989 288 7756
p130 shRbSenescentGSE19898 74937178 74937419 241 19302
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T30-glioblastomaGSE21026 74980875 74981878 1003 6250
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 74963772 74964249 477 0
PolII HeLaGSE12783 74956180 74959169 2989 0
TAF k562GSE8489 74958527 74959083 556 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-196a hsa-mir-196a-1 17 18663355
hsa-miR-196a hsa-mir-196a-2 12 18663355
hsa-miR-196b hsa-mir-196b 7 18663355
hsa-miR-21 hsa-mir-21 17 19737943
hsa-miR-21* hsa-mir-21 17 19737943
hsa-miR-584 hsa-mir-584 5 18663355
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
26587 mRNA ANXA1 chr9 72996334 73014861 18527 mRNA chr9 72935321 73068662 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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