AutismKB 2.0

Annotation Detail for HIST1H2AE


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Basic Information Top
Gene Symbol:HIST1H2AE ( H2A.1,H2A.2,H2A/a,H2AFA,HIST1H2AB )
Gene Full Name: histone cluster 1, H2ae
Band: 6p22.2
Quick LinksEntrez ID:3012; OMIM: 602786; Uniprot ID:H2A1B_HUMAN; ENSEMBL ID: ENSG00000168274; HGNC ID: 4724
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine.
2Phosphoserine (By similarity).
4Citrulline; alternate.
4Symmetric dimethylarginine; alternate (By
6N6-acetyllysine (By similarity).
121Phosphothreonine.
123Phosphoserine.
Location(AA) Modifications Resource
2N-acetylserine.Swiss-Prot 53.0
2Phosphoserine (By similarity).Swiss-Prot 53.0
4Citrulline; alternate.Swiss-Prot 53.0
4Symmetric dimethylarginine; alternate (Bysimilarity).Swiss-Prot 53.0
6N6-acetyllysine (By similarity).Swiss-Prot 53.0
120Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin).Swiss-Prot 53.0
121Phosphothreonine (Probable).Swiss-Prot 53.0
Location(AA) Modification Resource
17Phosphothreonine(PKC)HMM predict
20Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003513
  • Location:chr6 26141298-26141774
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 26144471 26144501 30 2712
Oct1 HelaGSE14283 26144471 26144501 30 2712
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 SGSE7516 26139886 26141903 2017 404
p130 G0GSE7516 26139771 26141863 2092 482
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 26141356 26141754 398 0
H3K4me3 colorectalcancer 26140886 26141939 1053 0
H3ac HepG2E 26140886 26141754 868 0
Pol2 GM12878GSE19551 26140638 26142256 1618 0
hScc1 BcellGSE12603 26141536 26141790 254 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7f hsa-let-7f-1 9 20969724
hsa-let-7f hsa-let-7f-2 X 20969724
hsa-let-7f hsa-let-7f-1 9 20969724
hsa-let-7f hsa-let-7f-2 X 20969724
hsa-miR-125b hsa-mir-125b-1 11 20969724
hsa-miR-125b hsa-mir-125b-2 21 20969724
hsa-miR-125b hsa-mir-125b-1 11 20969724
hsa-miR-125b hsa-mir-125b-2 21 20969724
hsa-miR-221 hsa-mir-221 X 20969724
hsa-miR-221 hsa-mir-221 X 20969724
hsa-miR-221* hsa-mir-221 X 20969724
hsa-miR-221* hsa-mir-221 X 20969724
hsa-miR-222 hsa-mir-222 X 20969724
hsa-miR-222 hsa-mir-222 X 20969724
hsa-miR-222* hsa-mir-222 X 20969724
hsa-miR-222* hsa-mir-222 X 20969724
hsa-miR-23a hsa-mir-23a 19 20969724
hsa-miR-23a hsa-mir-23a 19 20969724
hsa-miR-23a* hsa-mir-23a 19 20969724
hsa-miR-23a* hsa-mir-23a 19 20969724
hsa-miR-558 hsa-mir-558 2 20969724
hsa-miR-558 hsa-mir-558 2 20969724
hsa-miR-766 hsa-mir-766 X 20969724
hsa-miR-766 hsa-mir-766 X 20969724
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018