AutismKB 2.0

Annotation Detail for H2AFZ


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Basic Information Top
Gene Symbol:H2AFZ ( H2A.z,H2A/z,H2AZ,MGC117173 )
Gene Full Name: H2A histone family, member Z
Band: 4q23
Quick LinksEntrez ID:3015; OMIM: 142763; Uniprot ID:H2AZ_HUMAN; ENSEMBL ID: ENSG00000164032; HGNC ID: 4741
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
5N6-acetyllysine.
8N6-acetyllysine.
12N6-acetyllysine.
14N6-acetyllysine.
Location(AA) Modifications Resource
5N6-acetyllysine.Swiss-Prot 53.0
8N6-acetyllysine.Swiss-Prot 53.0
12N6-acetyllysine.Swiss-Prot 53.0
14N6-acetyllysine.Swiss-Prot 53.0
122Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin).Swiss-Prot 53.0
Location(AA) Modification Resource
21Phosphoserine(ATM)HMM predict
83Phosphothreonine(PKA)HMM predict
83Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002106
  • Location:chr4 101088266-101090534
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 101090822 101091101 279 427
H3K4me3 colorectalcancer 101091101 101091662 561 847
Pol2 GM12878GSE19551 101090106 101091237 1131 137
Rb QuiescentGSE19898 101090291 101091046 755 134
Rb SenescentGSE19898 101090143 101091184 1041 129
USF1 HepG2E 101090334 101091628 1294 447
USF2 HepG2E 101090822 101091597 775 675
c MYCMCF7 101090681 101091279 598 446
hScc1 BcellGSE12603 101090779 101091101 322 406
p130 QuiescentGSE19898 101090147 101090927 780 3
p130 shRbQuiescentGSE19898 101090150 101090964 814 23
p130 shRbSenescentGSE19898 101090171 101091209 1038 156
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 101089194 101089508 314 0
CTCF CD4SISSRdata 101089194 101089508 314 0
CTCF G2GSE9613 101088972 101090549 1577 0
E2F4 G0GSE7516 101089930 101091024 1094 0
Fos K562GSE19551 101090088 101090947 859 0
H3ac HepG2E 101087223 101089789 2566 0
LIN9 G0GSE7516 101089858 101091058 1200 0
NRSF mAbJurkat 101088282 101088681 399 0
PHF8 293TGSE20725 101089792 101091241 1449 0
PHF8 HeLaGSE20725 101089544 101091409 1865 0
PolII HeLaGSE12783 101088975 101091662 2687 0
Rb QuiescentGSE19898 101089154 101089917 763 0
TAF HelaGSE8489 101088779 101089930 1151 0
hScc1 BcellGSE12603 101088972 101089858 886 0
hScc1 CdLSGSE12603 101088972 101091058 2086 0
p130 SenescentGSE19898 101090118 101090882 764 0
p130 shRbQuiescentGSE19898 101089279 101089969 690 0
p130 G0GSE7516 101089930 101091024 1094 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018