Annotation Detail for HADHA
Basic Information Top
| Gene Symbol: | HADHA ( ECHA,GBP,HADH,LCEH,LCHAD,MGC1728,MTPA,TP-ALPHA ) |
|---|---|
| Gene Full Name: | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| Band: | 2p23.3 |
| Quick Links | Entrez ID:3030; OMIM: 600890; Uniprot ID:ECHA_HUMAN; ENSEMBL ID: ENSG00000084754; HGNC ID: 4801 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 129 | N6-acetyllysine (By similarity). | |
| 295 | N6-acetyllysine. | |
| 303 | N6-acetyllysine. | |
| 326 | N6-acetyllysine (By similarity). | |
| 350 | N6-acetyllysine (By similarity). | |
| 353 | N6-acetyllysine. | |
| 359 | N6-acetyllysine. | |
| 406 | N6-acetyllysine. | |
| 505 | N6-acetyllysine. | |
| 540 | N6-acetyllysine. | |
| 569 | N6-acetyllysine (By similarity). | |
| 644 | N6-acetyllysine. | |
| 728 | N6-acetyllysine (By similarity). | |
| 756 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 756 | Phosphoserine. | Swiss-Prot 53.0 |
| 756 | Phosphoserine | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 28 | N-linked | HMM predict |
| 63 | Phosphothreonine(PKC) | HMM predict |
| 142 | N-linked | HMM predict |
| 162 | Phosphothreonine(PKC) | HMM predict |
| 257 | Phosphoserine(CDC2) | HMM predict |
| 274 | Phosphothreonine(PKC) | HMM predict |
| 283 | Phosphotyrosine(Syk) | HMM predict |
| 320 | Phosphotyrosine(INSR) | HMM predict |
| 320 | Phosphotyrosine(Jak) | HMM predict |
| 406 | Methyllysine | HMM predict |
| 411 | Methyllysine | HMM predict |
| 428 | N-linked | HMM predict |
| 475 | N-linked | HMM predict |
| 482 | O-linked | HMM predict |
| 631 | O-linked | HMM predict |
| 632 | Phosphoserine(PKA) | HMM predict |
| 668 | Phosphoserine(CK2) | HMM predict |
| 669 | Phosphoserine(CK1) | HMM predict |
| 713 | S-palmitoyl | HMM predict |
| 756 | Phosphoserine(CDK) | HMM predict |
| 756 | Phosphoserine(CDC2) | HMM predict |
- RefSeq ID: NM_000182
- Location:chr2 26267008-26321097
- strand:-
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 26247976 | 26248139 | 163 | 18951 |
| CTCF | CD4 | GSE12889 | 26261121 | 26261371 | 250 | 5763 |
| CTCF | CD4 | SISSRdata | 26247976 | 26248139 | 163 | 18951 |
| CTCF | CD4 | SISSRdata | 26261121 | 26261371 | 250 | 5763 |
| CTCF | Jurkat | GSE12889 | 26247940 | 26248187 | 247 | 18945 |
| CTCF | G2 | GSE9613 | 26247221 | 26248167 | 946 | 19315 |
| CTCF | G2 | GSE9613 | 26249588 | 26250070 | 482 | 17180 |
| CTCF | G2 | GSE9613 | 26250752 | 26251287 | 535 | 15989 |
| CTCF | G2 | GSE9613 | 26252343 | 26252661 | 318 | 14507 |
| CTCF | G2 | GSE9613 | 26255397 | 26255819 | 422 | 11401 |
| CTCF | G2 | GSE9613 | 26258642 | 26259475 | 833 | 7950 |
| CTCF | G2 | GSE9613 | 26260625 | 26261778 | 1153 | 5807 |
| CTCF | G2 | GSE9613 | 26262290 | 26262727 | 437 | 4500 |
| CTCF | G2 | GSE9613 | 26263487 | 26264235 | 748 | 3148 |
| Myc | K562 | GSE19551 | 26260879 | 26261472 | 593 | 5833 |
| hScc1 | Bcell | GSE12603 | 26247975 | 26248167 | 192 | 18938 |
| hScc1 | Bcell | GSE12603 | 26249588 | 26249828 | 240 | 17301 |
| hScc1 | Bcell | GSE12603 | 26251420 | 26251776 | 356 | 15411 |
| hScc1 | Bcell | GSE12603 | 26260586 | 26261734 | 1148 | 5849 |
| hScc1 | Bcell | GSE12603 | 26263838 | 26264300 | 462 | 2940 |
| hScc1 | G2 | GSE9613 | 26247221 | 26248167 | 946 | 19315 |
| p130 | Senescent | GSE19898 | 26260841 | 26261057 | 216 | 6060 |
| p130 | shRbSenescent | GSE19898 | 26261033 | 26261208 | 175 | 5888 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 26267739 | 26268261 | 522 | 0 |
| CTCF | G2 | GSE9613 | 26320805 | 26321258 | 453 | 0 |
| H3K4me3 | colorectal | cancer | 26319624 | 26320805 | 1181 | 0 |
| H3ac | HepG2 | E | 26319590 | 26320884 | 1294 | 0 |
| LIN9 | G0 | GSE7516 | 26319667 | 26321022 | 1355 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 26276938 | 26276973 | 35 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 26279147 | 26279184 | 37 | 0 |
| Oct1 | Hela | GSE14283 | 26276936 | 26276972 | 36 | 0 |
| Oct1 | Hela | GSE14283 | 26279154 | 26279184 | 30 | 0 |
| TAF | Hela | GSE8489 | 26319590 | 26320805 | 1215 | 0 |
| TAF | k562 | GSE8489 | 26319590 | 26320884 | 1294 | 0 |
| p130 | Quiescent | GSE19898 | 26320174 | 26320547 | 373 | 0 |
| p130 | Senescent | GSE19898 | 26320048 | 26320860 | 812 | 0 |
| p130 | shRbQuiescent | GSE19898 | 26319808 | 26320802 | 994 | 0 |
| p130 | shRbSenescent | GSE19898 | 26320092 | 26320786 | 694 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 14041 | mRNA | chr2 | 26328738 | 26330967 | 210 | mRNA | HADHA | chr2 | 26325159 | 26379140 | Sense/Antisense (SA) pairs | |