AutismKB 2.0

Annotation Detail for HELLS


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Basic Information Top
Gene Symbol:HELLS ( FLJ10339,LSH,PASG,SMARCA6 )
Gene Full Name: helicase, lymphoid-specific
Band: 10q23.33
Quick LinksEntrez ID:3070; OMIM: 603946; Uniprot ID:HELLS_HUMAN; ENSEMBL ID: ENSG00000119969; HGNC ID: 4861
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
357DEAH box.
505Phosphothreonine.
832Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
9O-linkedHMM predict
12O-linkedHMM predict
143Phosphoserine(CK1)HMM predict
162N-linkedHMM predict
163Phosphoserine(CK1)HMM predict
164Phosphoserine(CK1)HMM predict
164Phosphoserine(CK2)HMM predict
167N-linkedHMM predict
294Phosphothreonine(PKA)HMM predict
322Phosphothreonine(PKA)HMM predict
391Phosphoserine(CK1)HMM predict
421Phosphoserine(CK2)HMM predict
485N-linkedHMM predict
490N-linkedHMM predict
512Phosphothreonine(PKA)HMM predict
512Phosphothreonine(PKC)HMM predict
514MethyllysineHMM predict
517N-linkedHMM predict
518Phosphotyrosine(INSR)HMM predict
571S-palmitoylHMM predict
682N-linkedHMM predict
780Phosphotyrosine(EGFR)HMM predict
780Phosphotyrosine(INSR)HMM predict
793Phosphoserine(CK2)HMM predict
836S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018063
  • Location:chr10 96295563-96351844
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
LIN9 SGSE7516 96294921 96296158 1237 24
Oct1 HelaGSE14283 96286455 96286491 36 9091
PHF8 HeLaGSE20725 96294847 96296032 1185 124
PHF8 Hs68minusFBSGSE20725 96294950 96295986 1036 96
Rb GrowingGSE19898 96295284 96295702 418 71
p130 shRbQuiescentGSE19898 96295092 96295989 897 23
p130 SGSE7516 96294991 96296124 1133 6
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 96295229 96296124 895 0
H3K4me3 colorectalcancer 96294991 96296530 1539 0
H3ac HepG2E 96294665 96297197 2532 0
LIN9 G0GSE7516 96295196 96296348 1152 0
Oct1 H2O2-HelaGSE14283 96324593 96324632 39 0
Oct1 H2O2-HelaGSE14283 96330945 96330973 28 0
Oct1 HelaGSE14283 96297754 96297792 38 0
Oct1 HelaGSE14283 96324593 96324633 40 0
PHF8 293TGSE20725 96295030 96296206 1176 0
Rb QuiescentGSE19898 96295373 96295957 584 0
Rb SenescentGSE19898 96295322 96296071 749 0
TAF HelaGSE8489 96294665 96296899 2234 0
TAF k562GSE8489 96295766 96296850 1084 0
hScc1 CdLSGSE12603 96316218 96316361 143 0
p130 QuiescentGSE19898 96295359 96296068 709 0
p130 SenescentGSE19898 96295160 96296338 1178 0
p130 shRbSenescentGSE19898 96295118 96296050 932 0
p130 G0GSE7516 96295229 96296270 1041 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-29a hsa-mir-29a 7 19959559
hsa-miR-29a* hsa-mir-29a 7 19959559
hsa-miR-29b hsa-mir-29b-1 7 19959559
hsa-miR-29b hsa-mir-29b-2 1 19959559
hsa-miR-29b-1* hsa-mir-29b-1 7 19959559
hsa-miR-29b-2* hsa-mir-29b-2 1 19959559
hsa-miR-29c hsa-mir-29c 1 19959559
hsa-miR-29c* hsa-mir-29c 1 19959559
hsa-miR-34a hsa-mir-34a 1 18823940
hsa-miR-34a* hsa-mir-34a 1 18823940
hsa-miR-7 hsa-mir-7-1 9 18823940
hsa-miR-7 hsa-mir-7-2 15 18823940
hsa-miR-7 hsa-mir-7-3 19 18823940
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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