AutismKB 2.0

Annotation Detail for HGF


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Basic Information Top
Gene Symbol:HGF ( DFNB39,F-TCF,HGFB,HPTA,SF )
Gene Full Name: hepatocyte growth factor (hepapoietin A; scatter factor)
Band: 7q21.11
Quick LinksEntrez ID:3082; OMIM: 142409,608265; Uniprot ID:HGF_HUMAN; ENSEMBL ID: ENSG00000019991; HGNC ID: 4893
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
32Pyrrolidone carboxylic acid.
294N-linked (GlcNAc...) (complex).
402N-linked (GlcNAc...) (complex).
476O-linked (GalNAc...).
566N-linked (GlcNAc...) (complex).
653N-linked (GlcNAc...) (complex).
Location(AA) Modifications Resource
32Pyrrolidone carboxylic acid.Swiss-Prot 53.0
294N-linked (GlcNAc...) (complex)./FTId=CAR
402N-linked (GlcNAc...) (complex)./FTId=CAR
475O-linkedOGlycBase6.0
476O-linked (GalNAc...)./FTId=CAR
566N-linked (GlcNAc...) (complex)./FTId=CAR
653N-linked (GlcNAc...) (complex)./FTId=CAR
Location(AA) Modification Resource
119Phosphotyrosine(INSR)HMM predict
239Phosphothreonine(CDC2)HMM predict
294N-linkedHMM predict
331Phosphoserine(ATM)HMM predict
340Phosphothreonine(MAPK)HMM predict
399Phosphotyrosine(INSR)HMM predict
402N-linkedHMM predict
404Phosphoserine(ATM)HMM predict
408Phosphoserine(IKK)HMM predict
602Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000601
  • Location:chr7 81169380-81237387
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 81151763 81152923 1160 17038
P300 T30-glioblastomaGSE21026 81151831 81153073 1242 16929
TFAP2C MCF7GSE21234 81152233 81152677 444 16926
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 81173231 81173267 36 0
Oct1 HelaGSE14283 81199394 81199426 32 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b* hsa-let-7b 22 19396864
hsa-let-7b* hsa-let-7b 22 19396864
hsa-let-7e* hsa-let-7e 19 19396864
hsa-let-7e* hsa-let-7e 19 19396864
hsa-miR-1 hsa-mir-1-2 18 21311168
hsa-miR-1 hsa-mir-1-1 20 21311168
hsa-miR-1 hsa-mir-1-2 18 21311168
hsa-miR-1 hsa-mir-1-1 20 21311168
hsa-miR-1228* hsa-mir-1228 12 19396864
hsa-miR-1228* hsa-mir-1228 12 19396864
hsa-miR-127-3p hsa-mir-127 14 19396864
hsa-miR-127-3p hsa-mir-127 14 19396864
hsa-miR-144* hsa-mir-144 17 19396864
hsa-miR-144* hsa-mir-144 17 19396864
hsa-miR-195* hsa-mir-195 17 19396864
hsa-miR-195* hsa-mir-195 17 19396864
hsa-miR-203 hsa-mir-203 14 19396864
hsa-miR-203 hsa-mir-203 14 19396864
hsa-miR-299-3p hsa-mir-299 14 19396864
hsa-miR-299-3p hsa-mir-299 14 19396864
hsa-miR-301a hsa-mir-301a 17 19396864
hsa-miR-301a hsa-mir-301a 17 19396864
hsa-miR-30b* hsa-mir-30b 8 19396864
hsa-miR-30b* hsa-mir-30b 8 19396864
hsa-miR-32* hsa-mir-32 9 19396864
hsa-miR-32* hsa-mir-32 9 19396864
hsa-miR-340* hsa-mir-340 5 19396864
hsa-miR-340* hsa-mir-340 5 19396864
hsa-miR-345 hsa-mir-345 14 19396864
hsa-miR-345 hsa-mir-345 14 19396864
hsa-miR-34a* hsa-mir-34a 1 19396864
hsa-miR-34a* hsa-mir-34a 1 19396864
hsa-miR-379 hsa-mir-379 14 19396864
hsa-miR-379 hsa-mir-379 14 19396864
hsa-miR-379* hsa-mir-379 14 19396864
hsa-miR-379* hsa-mir-379 14 19396864
hsa-miR-423-3p hsa-mir-423 17 19396864
hsa-miR-423-3p hsa-mir-423 17 19396864
hsa-miR-423-5p hsa-mir-423 17 19396864
hsa-miR-423-5p hsa-mir-423 17 19396864
hsa-miR-455-3p hsa-mir-455 9 19396864
hsa-miR-455-3p hsa-mir-455 9 19396864
hsa-miR-483-3p hsa-mir-483 11 19396864
hsa-miR-483-3p hsa-mir-483 11 19396864
hsa-miR-519c-3p hsa-mir-519c 19 20233879
hsa-miR-519c-3p hsa-mir-519c 19 20233879
hsa-miR-519c-5p hsa-mir-519c 19 20233879
hsa-miR-519c-5p hsa-mir-519c 19 20233879
hsa-miR-582-3p hsa-mir-582 5 19396864
hsa-miR-582-3p hsa-mir-582 5 19396864
hsa-miR-582-5p hsa-mir-582 5 19396864
hsa-miR-582-5p hsa-mir-582 5 19396864
hsa-miR-584 hsa-mir-584 5 19396864
hsa-miR-584 hsa-mir-584 5 19396864
hsa-miR-595 hsa-mir-595 7 19396864
hsa-miR-595 hsa-mir-595 7 19396864
hsa-miR-615-3p hsa-mir-615 12 19396864
hsa-miR-615-3p hsa-mir-615 12 19396864
hsa-miR-7-1* hsa-mir-7-1 9 19396864
hsa-miR-7-1* hsa-mir-7-1 9 19396864
hsa-miR-885-3p hsa-mir-885 3 19396864
hsa-miR-885-3p hsa-mir-885 3 19396864
hsa-miR-9 hsa-mir-9-1 1 19396864
hsa-miR-9 hsa-mir-9-2 5 19396864
hsa-miR-9 hsa-mir-9-3 15 19396864
hsa-miR-9 hsa-mir-9-1 1 19396864
hsa-miR-9 hsa-mir-9-2 5 19396864
hsa-miR-9 hsa-mir-9-3 15 19396864
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018