AutismKB 2.0

Annotation Detail for HIVEP2


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Basic Information Top
Gene Symbol:HIVEP2 ( HIV-EP2,MBP-2,MIBP1,SHN2,ZAS2,ZNF40B )
Gene Full Name: human immunodeficiency virus type I enhancer binding protein 2
Band: 6q24.2
Quick LinksEntrez ID:3097; OMIM: 143054; Uniprot ID:ZEP2_HUMAN; ENSEMBL ID: ENSG00000010818; HGNC ID: 4921
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
943Nuclear localization signal (Potential).
2071Phosphoserine.
2077Phosphoserine.
Location(AA) Modifications Resource
2130PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
13Phosphothreonine(PKC)HMM predict
66Phosphoserine(CDK)HMM predict
71Phosphoserine(MAPK)HMM predict
156Phosphoserine(PKA)HMM predict
156Phosphoserine(PKG)HMM predict
189Phosphotyrosine(INSR)HMM predict
194S-palmitoylHMM predict
217Phosphotyrosine(EGFR)HMM predict
273Phosphoserine(CK1)HMM predict
273Phosphoserine(CK2)HMM predict
279Phosphothreonine(CK2)HMM predict
281Phosphothreonine(CK2)HMM predict
296Phosphoserine(IKK)HMM predict
339N-linkedHMM predict
344Phosphotyrosine(INSR)HMM predict
344Phosphotyrosine(Syk)HMM predict
389Phosphoserine(MAPK)HMM predict
392Phosphoserine(IKK)HMM predict
404Phosphoserine(CK2)HMM predict
406Phosphoserine(CK1)HMM predict
406Phosphoserine(IKK)HMM predict
406PhosphoserineHMM predict
433Phosphoserine(CDC2)HMM predict
439O-linkedHMM predict
476Phosphoserine(ATM)HMM predict
476Phosphoserine(IKK)HMM predict
488Phosphoserine(ATM)HMM predict
488Phosphoserine(IKK)HMM predict
491Phosphoserine(IKK)HMM predict
545Phosphoserine(IKK)HMM predict
549Phosphoserine(IKK)HMM predict
550O-linkedHMM predict
552O-linkedHMM predict
553N-linkedHMM predict
555O-linkedHMM predict
565Phosphoserine(CK2)HMM predict
629Phosphoserine(CDC2)HMM predict
658Phosphotyrosine(Syk)HMM predict
769O-linkedHMM predict
774O-linkedHMM predict
787Phosphoserine(CK1)HMM predict
807Phosphoserine(CK1)HMM predict
813Phosphoserine(IKK)HMM predict
817Phosphoserine(CK2)HMM predict
832Phosphoserine(CDC2)HMM predict
832Phosphoserine(CDK)HMM predict
836O-linkedHMM predict
842O-linkedHMM predict
864Phosphoserine(CDC2)HMM predict
866O-linkedHMM predict
866Phosphoserine(ATM)HMM predict
928Phosphoserine(ATM)HMM predict
951Phosphoserine(ATM)HMM predict
954Phosphoserine(CK2)HMM predict
955Phosphoserine(IKK)HMM predict
964O-linkedHMM predict
966Phosphoserine(CDC2)HMM predict
966Phosphoserine(ATM)HMM predict
968Phosphoserine(PKC)HMM predict
968Phosphoserine(CK1)HMM predict
968Phosphoserine(ATM)HMM predict
968Phosphoserine(IKK)HMM predict
968PhosphoserineHMM predict
972N-linkedHMM predict
989Phosphoserine(CK1)HMM predict
992Phosphoserine(PKG)HMM predict
1017Phosphoserine(ATM)HMM predict
1053Phosphotyrosine(INSR)HMM predict
1055N-linkedHMM predict
1062O-linkedHMM predict
1068O-linkedHMM predict
1068O-linkedHMM predict
1068Phosphothreonine(PKC)HMM predict
1070Phosphoserine(CDC2)HMM predict
1085Phosphoserine(CAMK2)HMM predict
1085Phosphoserine(IKK)HMM predict
1087Phosphoserine(ATM)HMM predict
1089Phosphoserine(CDC2)HMM predict
1089Phosphoserine(ATM)HMM predict
1093Phosphoserine(ATM)HMM predict
1147O-linkedHMM predict
1163Phosphoserine(ATM)HMM predict
1179Phosphothreonine(PKC)HMM predict
1302Phosphoserine(IKK)HMM predict
1303Phosphoserine(CK1)HMM predict
1305Phosphoserine(CK1)HMM predict
1308Phosphothreonine(MAPK)HMM predict
1308Phosphothreonine(CDK)HMM predict
1328Phosphoserine(IKK)HMM predict
1372N-linkedHMM predict
1431Phosphoserine(IKK)HMM predict
1443Phosphoserine(CAMK2)HMM predict
1443Phosphoserine(CDC2)HMM predict
1443Phosphoserine(ATM)HMM predict
1466Phosphotyrosine(EGFR)HMM predict
1466Phosphotyrosine(SRC)HMM predict
1466Phosphotyrosine(Abl)HMM predict
1514Phosphoserine(IKK)HMM predict
1516Phosphoserine(CK1)HMM predict
1517O-linkedHMM predict
1519Phosphoserine(CDC2)HMM predict
1519Phosphoserine(MAPK)HMM predict
1519Phosphoserine(ATM)HMM predict
1519Phosphoserine(IKK)HMM predict
1521Phosphoserine(CK1)HMM predict
1523Phosphoserine(ATM)HMM predict
1526Phosphotyrosine(Syk)HMM predict
1528O-linkedHMM predict
1528Phosphoserine(ATM)HMM predict
1530Phosphoserine(CDC2)HMM predict
1566Phosphoserine(CK1)HMM predict
1566Phosphoserine(CK2)HMM predict
1579Phosphoserine(IKK)HMM predict
1584Phosphoserine(IKK)HMM predict
1586Phosphoserine(IKK)HMM predict
1653N-linkedHMM predict
1658N-linkedHMM predict
1681N-linkedHMM predict
1686N-linkedHMM predict
1690Phosphothreonine(PKA)HMM predict
1799Phosphotyrosine(INSR)HMM predict
1799Phosphotyrosine(Jak)HMM predict
1804S-palmitoylHMM predict
1812Phosphoserine(PKC)HMM predict
1841N-linkedHMM predict
1889O-linkedHMM predict
1898Phosphoserine(CK2)HMM predict
1928Phosphothreonine(MAPK)HMM predict
1935O-linkedHMM predict
1935Phosphoserine(PKG)HMM predict
1935Phosphoserine(PKB)HMM predict
1936Phosphothreonine(PKA)HMM predict
1937Phosphoserine(CDC2)HMM predict
1937Phosphoserine(CDK)HMM predict
1937Phosphoserine(ATM)HMM predict
1937Phosphoserine(IKK)HMM predict
1944O-linkedHMM predict
1945Phosphoserine(PKB)HMM predict
1961Phosphoserine(CK1)HMM predict
1962Phosphoserine(CK1)HMM predict
1981O-linkedHMM predict
1985Phosphothreonine(MAPK)HMM predict
2007Phosphothreonine(CK2)HMM predict
2035O-linkedHMM predict
2035Phosphoserine(ATM)HMM predict
2040Phosphoserine(PKB)HMM predict
2046Phosphoserine(CK1)HMM predict
2071PhosphoserineHMM predict
2089PhosphoserineHMM predict
2106PhosphoserineHMM predict
2112Phosphoserine(CDC2)HMM predict
2112Phosphoserine(CDK)HMM predict
2118Phosphoserine(CDC2)HMM predict
2130Phosphoserine(CDC2)HMM predict
2130PhosphoserineHMM predict
2145Phosphoserine(CDC2)HMM predict
2145PhosphoserineHMM predict
2194Phosphotyrosine(SRC)HMM predict
2250Phosphoserine(CDK)HMM predict
2250PhosphoserineHMM predict
2264O-linkedHMM predict
2292O-linkedHMM predict
2293O-linkedHMM predict
2297O-linkedHMM predict
2297Phosphoserine(IKK)HMM predict
2298O-linkedHMM predict
2298O-linkedHMM predict
2298Phosphothreonine(CDC2)HMM predict
2298Phosphothreonine(MAPK)HMM predict
2298Phosphothreonine(CDK)HMM predict
2301Phosphoserine(CDC2)HMM predict
2301Phosphoserine(MAPK)HMM predict
2301Phosphoserine(CDK)HMM predict
2301PhosphoserineHMM predict
2309Phosphoserine(PKG)HMM predict
2314Phosphoserine(IKK)HMM predict
2316N-linkedHMM predict
2383O-linkedHMM predict
2402Phosphothreonine(MAPK)HMM predict
2429Phosphoserine(CK1)HMM predict
2429Phosphoserine(CK2)HMM predict
2430Phosphoserine(CK1)HMM predict
2431Phosphoserine(CK1)HMM predict
2431Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006734
  • Location:chr6 143114297-143308030
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 143305772 143310736 4964 224
CTCF CD4GSE12889 143316676 143316844 168 8730
CTCF CD4SISSRdata 143316676 143316844 168 8730
CTCF G2GSE9613 143307354 143309393 2039 343
CTCF G2GSE9613 143309717 143310229 512 1943
Oct1 HelaGSE14283 143321603 143321652 49 13597
Pol2 GM12878GSE19551 143306582 143310597 4015 559
TFAP2C MCF7GSE21234 143309124 143309420 296 1242
hScc1 BcellGSE12603 143307318 143308885 1567 71
hScc1 BcellGSE12603 143309717 143310368 651 2012
hScc1 G2GSE9613 143307498 143309294 1796 366
p130 SenescentGSE19898 143310409 143310910 501 2629
p130 shRbQuiescentGSE19898 143310429 143310783 354 2576
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 143109486 143109666 180 4722
CTCF CD4SISSRdata 143109486 143109666 180 4722
Oct1 H2O2-HelaGSE14283 143099261 143099294 33 15020
Oct1 H2O2-HelaGSE14283 143108656 143108702 46 5619
Oct1 HelaGSE14283 143094672 143094739 67 19592
Oct1 HelaGSE14283 143097635 143097677 42 16642
Oct1 HelaGSE14283 143099263 143099294 31 15019
Oct1 HelaGSE14283 143104385 143104419 34 9896
Oct1 HelaGSE14283 143108656 143108699 43 5620
RNAII Tamoxifen-MCF7GSE14664 143112043 143112143 100 2205
hScc1 BcellGSE12603 143096328 143096509 181 17879
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 143140472 143140686 214 0
CBP T30-glioblastomaGSE21026 143265330 143266027 697 0
CTCF CD4GSE12889 143185840 143186076 236 0
CTCF CD4GSE12889 143276311 143276801 490 0
CTCF CD4SISSRdata 143185840 143186076 236 0
CTCF CD4SISSRdata 143276311 143276801 490 0
CTCF G2GSE9613 143119072 143119275 203 0
CTCF G2GSE9613 143121270 143121414 144 0
CTCF G2GSE9613 143134236 143134382 146 0
CTCF G2GSE9613 143184650 143184992 342 0
CTCF G2GSE9613 143185667 143186013 346 0
CTCF G2GSE9613 143208743 143208888 145 0
CTCF G2GSE9613 143238012 143238515 503 0
CTCF G2GSE9613 143241414 143241556 142 0
CTCF G2GSE9613 143289620 143290010 390 0
ER E2-MCF7GSE14664 143209257 143209296 39 0
ER E2-MCF7GSE14664 143251434 143251466 32 0
ER E2-MCF7GSE14664 143281350 143281396 46 0
FoxA1 MCF7MACSdata 143205589 143205946 357 0
FoxA1 MCF7MACSdata 143305778 143306044 266 0
H3ac HepG2E 143290533 143290867 334 0
H3ac HepG2E 143306932 143307711 779 0
KLF4 hESGSE17917 143289519 143289896 377 0
Oct1 H2O2-HelaGSE14283 143118674 143118704 30 0
Oct1 H2O2-HelaGSE14283 143122884 143122913 29 0
Oct1 H2O2-HelaGSE14283 143132563 143132590 27 0
Oct1 H2O2-HelaGSE14283 143170944 143170994 50 0
Oct1 H2O2-HelaGSE14283 143219975 143220002 27 0
Oct1 H2O2-HelaGSE14283 143233356 143233383 27 0
Oct1 HelaGSE14283 143118667 143118704 37 0
Oct1 HelaGSE14283 143121181 143121212 31 0
Oct1 HelaGSE14283 143132564 143132595 31 0
Oct1 HelaGSE14283 143140914 143140969 55 0
Oct1 HelaGSE14283 143148634 143148667 33 0
Oct1 HelaGSE14283 143170721 143170761 40 0
Oct1 HelaGSE14283 143170940 143170996 56 0
Oct1 HelaGSE14283 143203390 143203426 36 0
Oct1 HelaGSE14283 143209252 143209304 52 0
P300 T30-glioblastomaGSE21026 143164874 143165604 730 0
P300 T30-glioblastomaGSE21026 143234488 143235347 859 0
P300 T30-glioblastomaGSE21026 143247389 143248983 1594 0
P300 T30-glioblastomaGSE21026 143265176 143266375 1199 0
PHF8 293TGSE20725 143307218 143308440 1222 0
PHF8 Hs68minusFBSGSE20725 143289180 143290130 950 0
RARA MCF7GSE15244 143187357 143187889 532 0
RARA MCF7GSE15244 143205305 143206317 1012 0
RARA MCF7GSE15244 143208185 143208707 522 0
RARG MCF7GSE15244 143187357 143187742 385 0
TFAP2C MCF7GSE21234 143185743 143186510 767 0
TFAP2C MCF7GSE21234 143190176 143190596 420 0
TFAP2C MCF7GSE21234 143208434 143209112 678 0
TFAP2C MCF7GSE21234 143215936 143216635 699 0
VDR GM10855-stimGSE22484 143163727 143167902 4175 0
VDR GM10855-stimGSE22484 143169358 143170914 1556 0
VDR GM10861-stimGSE22484 143163928 143168047 4119 0
VDR GM10861-stimGSE22484 143169408 143171083 1675 0
hScc1 BcellGSE12603 143208595 143208984 389 0
hScc1 BcellGSE12603 143249816 143250100 284 0
hScc1 BcellGSE12603 143276277 143276842 565 0
hScc1 CdLSGSE12603 143182638 143183244 606 0
hScc1 CdLSGSE12603 143249514 143249963 449 0
hScc1 CdLSGSE12603 143275695 143276842 1147 0
p130 QuiescentGSE19898 143307246 143307658 412 0
p130 SenescentGSE19898 143208793 143209030 237 0
p130 shRbQuiescentGSE19898 143307097 143307609 512 0
p130 shRbSenescentGSE19898 143307224 143307775 551 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-155 hsa-mir-155 21 20427544
hsa-miR-155 hsa-mir-155 21 18367535
hsa-miR-155* hsa-mir-155 21 20427544
hsa-miR-155* hsa-mir-155 21 18367535
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23266 EST chr6 143111272 143116589 254 mRNA HIVEP2 chr6 143114298 143137675Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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