AutismKB 2.0

Annotation Detail for HK1


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Basic Information Top
Gene Symbol:HK1 ( HK1-ta,HK1-tb,HK1-tc,HKI,HXK1 )
Gene Full Name: hexokinase 1
Band: 10q22.1
Quick LinksEntrez ID:3098; OMIM: 142600; Uniprot ID:HXK1_HUMAN; ENSEMBL ID: ENSG00000156515; HGNC ID: 4922
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
27Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
56N-linkedHMM predict
112Phosphotyrosine(SRC)HMM predict
112Phosphotyrosine(INSR)HMM predict
112Phosphotyrosine(Abl)HMM predict
112Phosphotyrosine(Syk)HMM predict
199Phosphotyrosine(INSR)HMM predict
208N-linkedHMM predict
219SulfotyrosineHMM predict
335N-linkedHMM predict
408Phosphothreonine(PKA)HMM predict
519Phosphothreonine(PKA)HMM predict
588Phosphotyrosine(INSR)HMM predict
656N-linkedHMM predict
667Phosphotyrosine(Syk)HMM predict
733Phosphoserine(CK1)HMM predict
741Phosphotyrosine(INSR)HMM predict
741Phosphotyrosine(EGFR)HMM predict
810N-linkedHMM predict
855N-linkedHMM predict
913Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000188
  • Location:chr10 70748628-70831640
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 70803729 70806182 2453 0
CTCF CD4GSE12889 70822350 70822683 333 0
CTCF CD4SISSRdata 70822350 70822683 333 0
CTCF HelaGSE12889 70822224 70822624 400 0
CTCF JurkatGSE12889 70822285 70822567 282 0
ER E2-MCF7GSE14664 70752276 70752324 48 0
ER MCF7GSE19013 70748915 70749663 748 0
ER MCF7GSE19013 70772042 70772285 243 0
FOXA1 MCF7GSE15244 70790408 70791489 1081 0
FoxA1 MCF7MACSdata 70790566 70790788 222 0
LIN9 G0GSE7516 70749180 70749734 554 0
Nanog hESGSE18292 70759240 70759898 658 0
Nanog hESGSE18292 70766980 70767530 550 0
Oct1 H2O2-HelaGSE14283 70766234 70766262 28 0
Oct1 H2O2-HelaGSE14283 70783771 70783803 32 0
Oct1 H2O2-HelaGSE14283 70795765 70795794 29 0
Oct1 H2O2-HelaGSE14283 70829324 70829352 28 0
Oct1 HelaGSE14283 70755941 70755972 31 0
Oct1 HelaGSE14283 70757089 70757127 38 0
Oct1 HelaGSE14283 70782726 70782762 36 0
Oct1 HelaGSE14283 70783771 70783802 31 0
Oct1 HelaGSE14283 70795715 70795795 80 0
Oct1 HelaGSE14283 70829324 70829353 29 0
RARA MCF7GSE15244 70762439 70763368 929 0
RARG MCF7GSE15244 70762439 70763167 728 0
RARG MCF7GSE15244 70789564 70789909 345 0
RARG MCF7GSE15244 70815910 70816224 314 0
RNAII Tamoxifen-MCF7GSE14664 70795764 70795804 40 0
Rb SenescentGSE19898 70822298 70822565 267 0
Sox2 hESGSE18292 70767206 70767493 287 0
TFAP2C MCF7GSE21234 70762731 70763615 884 0
TFAP2C MCF7GSE21234 70792056 70792601 545 0
TFAP2C MCF7GSE21234 70817278 70817576 298 0
hScc1 BcellGSE12603 70748477 70748868 391 0
hScc1 BcellGSE12603 70778824 70779261 437 0
hScc1 BcellGSE12603 70812206 70812421 215 0
hScc1 BcellGSE12603 70821547 70822621 1074 0
hScc1 CdLSGSE12603 70748045 70749551 1506 0
hScc1 CdLSGSE12603 70822075 70822621 546 0
hScc1 G2GSE9613 70822229 70822621 392 0
p130 shRbQuiescentGSE19898 70822162 70822605 443 0
p63 keratinocytesGSE17611 70814150 70815864 1714 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 20440510
hsa-let-7a hsa-let-7a-2 11 20440510
hsa-let-7a hsa-let-7a-3 22 20440510
hsa-let-7a* hsa-let-7a-1 9 20440510
hsa-let-7a* hsa-let-7a-3 22 20440510
hsa-let-7b hsa-let-7b 22 20440510
hsa-let-7b* hsa-let-7b 22 20440510
hsa-let-7c hsa-let-7c 21 20440510
hsa-let-7c* hsa-let-7c 21 20440510
hsa-let-7d hsa-let-7d 9 20440510
hsa-let-7d* hsa-let-7d 9 20440510
hsa-let-7e hsa-let-7e 19 20440510
hsa-let-7e* hsa-let-7e 19 20440510
hsa-let-7f hsa-let-7f-1 9 20440510
hsa-let-7f hsa-let-7f-2 X 20440510
hsa-let-7f-1* hsa-let-7f-1 9 20440510
hsa-let-7f-2* hsa-let-7f-2 X 20440510
hsa-let-7g hsa-let-7g 3 20440510
hsa-let-7g* hsa-let-7g 3 20440510
hsa-let-7i hsa-let-7i 12 20440510
hsa-let-7i* hsa-let-7i 12 20440510
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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