AutismKB 2.0

Annotation Detail for HLA-A


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Basic Information Top
Gene Symbol:HLA-A ( FLJ26655,HLAA )
Gene Full Name: major histocompatibility complex, class I, A
Band: 6p22.1
Quick LinksEntrez ID:3105; OMIM: 142800; Uniprot ID:1A03_HUMAN; ENSEMBL ID: ENSG00000206503; HGNC ID: 4931
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
110N-linked (GlcNAc...) (By similarity).
Location(AA) Modifications Resource
110N-linked (GlcNAc...) (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
110N-linkedHMM predict
147Phosphotyrosine(INSR)HMM predict
281Phosphotyrosine(EGFR)HMM predict
295Phosphothreonine(PKC)HMM predict
302Phosphoserine(ATM)HMM predict
337Phosphoserine(PKG)HMM predict
337Phosphoserine(PKB)HMM predict
359Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002116
  • Location:chr6 30018309-30021631
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 30002896 30003060 164 15332
CTCF CD4SISSRdata 30002896 30003060 164 15332
CTCF G2GSE9613 30002538 30003399 861 15341
CTCF G2GSE9613 30004006 30004139 133 14237
H3ac HepG2E 30016639 30018265 1626 858
NFkBII GM10847GSE19485 30001699 30003434 1735 15743
NFkBII GM10847GSE19485 30017364 30018893 1529 181
NFkBII GM12878GSE19485 30017144 30018901 1757 287
NFkBII GM12892GSE19485 30017202 30018922 1720 248
NFkBII GM15510GSE19485 30017344 30018942 1598 167
NFkBII GM18505GSE19485 30001684 30003423 1739 15756
NFkBII GM18505GSE19485 30017396 30018835 1439 194
NFkBII GM18526GSE19485 30017396 30018830 1434 197
Oct1 H2O2-HelaGSE14283 30015504 30015531 27 2792
Oct1 HelaGSE14283 30000499 30000528 29 17796
PHF8 293TGSE20725 30017863 30018721 858 18
Rb GrowingGSE19898 30002552 30002691 139 15688
TAFII hESGSE17917 30018104 30018425 321 45
hScc1 BcellGSE12603 30002414 30003224 810 15491
p130 QuiescentGSE19898 30002341 30002760 419 15759
p130 SenescentGSE19898 30002518 30002886 368 15608
p130 SenescentGSE19898 30017906 30018198 292 258
p130 SenescentGSE19898 30018208 30018340 132 36
p130 shRbQuiescentGSE19898 30002176 30002902 726 15771
p130 shRbQuiescentGSE19898 30002994 30003465 471 15080
p130 shRbSenescentGSE19898 30002472 30002803 331 15672
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 30024302 30024373 71 2706
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 30018083 30018740 657 0
CTCF G2GSE9613 30020316 30020465 149 0
PHF8 HeLaGSE20725 30017782 30018876 1094 0
Pol2 GM12878GSE19551 30017746 30019194 1448 0
hScc1 BcellGSE12603 30018155 30018934 779 0
p130 shRbSenescentGSE19898 30018220 30018430 210 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-146a hsa-mir-146a 5 19187610
hsa-miR-146a* hsa-mir-146a 5 19187610
hsa-miR-15a hsa-mir-15a 13 19187610
hsa-miR-15a* hsa-mir-15a 13 19187610
hsa-miR-181a hsa-mir-181a-2 9 19187610
hsa-miR-181a hsa-mir-181a-1 1 19187610
hsa-miR-181b hsa-mir-181b-1 1 19187610
hsa-miR-181b hsa-mir-181b-2 9 19187610
hsa-miR-200b hsa-mir-200b 1 19187610
hsa-miR-200b* hsa-mir-200b 1 19187610
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018