Annotation Detail for HLA-E

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Basic Information Top

Gene Symbol:	HLA-E ( DKFZp686P19218,EA1.2,EA2.1,HLA-6.2,MHC,QA1 )
Gene Full Name:	major histocompatibility complex, class I, E
Band:	6p22.1
Quick Links	Entrez ID:3133; OMIM: 143010; Uniprot ID:HLAE_HUMAN; ENSEMBL ID: ENSG00000204592; HGNC ID: 4962
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
107	N-linked (GlcNAc...).

Location(AA)	Modifications	Resource
107	N-linked (GlcNAc...) (By similarity).	Swiss-Prot 53.0

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	30557898	30558209	311	7196
CTCF	CD4	SISSRdata	30557898	30558209	311	7196
CTCF	G2	GSE9613	30556155	30556504	349	8920
CTCF	G2	GSE9613	30557661	30558319	658	7260
CTCF	G2	GSE9613	30559451	30559683	232	5683
Fos	K562	GSE19551	30564861	30565519	658	60
H3K27me3	colorectal	cancer	30545418	30546173	755	19454
H3K27me3	colorectal	cancer	30556379	30557409	1030	8356
H3ac	HepG2	E	30565101	30565280	179	59
Nanog	hES	GSE18292	30559526	30559744	218	5615
Oct1	Hela	GSE14283	30565166	30565207	41	63
P300	T0-glioblastoma	GSE21026	30564705	30565631	926	82
STAT1	HeLa	GSE12783	30563390	30566952	3562	79
Sox2	hES	GSE18292	30559512	30559753	241	5617
TAFII	hES	GSE17917	30564854	30565502	648	72
USF1	HepG2	E	30565101	30565352	251	23
USF2	HepG2	E	30565101	30565333	232	33
hScc1	Bcell	GSE12603	30557661	30558319	658	7260
hScc1	Bcell	GSE12603	30559451	30559683	232	5683
hScc1	CdLS	GSE12603	30557661	30558319	658	7260
hScc1	CdLS	GSE12603	30559379	30559683	304	5719
hScc1	G2	GSE9613	30557731	30558319	588	7225
hScc1	G2	GSE9613	30559417	30559683	266	5700

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
GABP	k562	GSE8489	30584680	30585362	682	15958
Oct1	Hela	GSE14283	30574205	30574257	52	5168
Oct1	Hela	GSE14283	30585378	30585407	29	16329
hScc1	CdLS	GSE12603	30572383	30572757	374	3507

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	30565457	30566328	871
ER	MCF7	E	30567859	30568175	316
H3K4me3	colorectal	cancer	30566538	30567219	681
PHF8	Hs68minusFBS	GSE20725	30564774	30566228	1454
PHF8	Hs68plusFBS	GSE20725	30564942	30566432	1490
Pol2	GM12878	GSE19551	30564860	30566725	1865
PolII	HeLa	GSE12783	30564692	30567028	2336
Rb	Growing	GSE19898	30565864	30566059	195
hScc1	Bcell	GSE12603	30565101	30565814	713

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-1	hsa-mir-1-2	18	20841498
hsa-miR-1	hsa-mir-1-1	20	20841498
hsa-miR-10b	hsa-mir-10b	2	20841498
hsa-miR-10b*	hsa-mir-10b	2	20841498
hsa-miR-124	hsa-mir-124-1	8	21131957
hsa-miR-124	hsa-mir-124-2	8	21131957
hsa-miR-124	hsa-mir-124-3	20	21131957
hsa-miR-148a	hsa-mir-148a	7	21068402
hsa-miR-148a*	hsa-mir-148a	7	21068402
hsa-miR-148b	hsa-mir-148b	12	21068402
hsa-miR-148b*	hsa-mir-148b	12	21068402
hsa-miR-152	hsa-mir-152	17	21068402
hsa-miR-181a	hsa-mir-181a-2	9	19801983
hsa-miR-181a	hsa-mir-181a-1	1	19801983
hsa-miR-208b	hsa-mir-208b	14	20447577
hsa-miR-27a	hsa-mir-27a	19	21149577
hsa-miR-27a*	hsa-mir-27a	19	21149577
hsa-miR-499-3p	hsa-mir-499	20	20447577
hsa-miR-499-5p	hsa-mir-499	20	20447577
hsa-miR-520b	hsa-mir-520b	19	19109132

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018