AutismKB 2.0

Annotation Detail for HLA-G


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Basic Information Top
Gene Symbol:HLA-G ( MHC-G )
Gene Full Name: major histocompatibility complex, class I, G
Band: 6p22.1
Quick LinksEntrez ID:3135; OMIM: 142871; Uniprot ID:HLAG_HUMAN; ENSEMBL ID: ENSG00000204632; HGNC ID: 4964
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
110N-linked (GlcNAc...) (By similarity).
Location(AA) Modifications Resource
110N-linked (GlcNAc...) (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
83Phosphotyrosine(INSR)HMM predict
91Phosphothreonine(PKA)HMM predict
110N-linkedHMM predict
115Phosphoserine(CK1)HMM predict
116Phosphoserine(CK1)HMM predict
281Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002127
  • Location:chr6 29903496-29906855
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 29888744 29889149 405 14550
ER E2-MCF7GSE14664 29885324 29885356 32 18157
H3K27me3 colorectalcancer 29902072 29903222 1150 850
Oct1 HelaGSE14283 29890052 29890079 27 13431
Oct1 HelaGSE14283 29899011 29899045 34 4469
TFAP2C MCF7GSE21234 29888771 29889343 572 14440
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 29910645 29910932 287 3933
CTCF CD4GSE12889 29923805 29924237 432 17166
CTCF CD4SISSRdata 29910645 29910932 287 3933
CTCF CD4SISSRdata 29923805 29924237 432 17166
CTCF HelaGSE12889 29910714 29910904 190 3954
CTCF HelaGSE12889 29923769 29924170 401 17114
CTCF JurkatGSE12889 29923883 29924240 357 17206
CTCF G2GSE9613 29909902 29910045 143 3118
CTCF G2GSE9613 29910705 29911025 320 4010
CTCF G2GSE9613 29923240 29924501 1261 17015
GABP k562GSE8489 29920643 29920788 145 13860
Myc K562GSE19551 29923748 29924203 455 17120
Nanog hESGSE18292 29920287 29920587 300 13582
Oct1 H2O2-HelaGSE14283 29919846 29919877 31 13006
Oct1 HelaGSE14283 29913142 29913174 32 6303
Oct1 HelaGSE14283 29919833 29919888 55 13005
Oct4 hESGSE17917 29923846 29924338 492 17237
hScc1 BcellGSE12603 29910705 29911162 457 4078
hScc1 BcellGSE12603 29923240 29924397 1157 16963
hScc1 CdLSGSE12603 29910705 29911458 753 4226
hScc1 CdLSGSE12603 29923578 29924433 855 17150
hScc1 G2GSE9613 29909902 29910272 370 3232
hScc1 G2GSE9613 29910705 29911126 421 4060
hScc1 G2GSE9613 29923578 29924711 1133 17289
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 29903742 29904144 402 0
Oct1 HelaGSE14283 29904518 29904573 55 0
hScc1 BcellGSE12603 29903620 29904240 620 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1224-5p hsa-mir-1224 3 19664672
hsa-miR-1262 hsa-mir-1262 1 19664672
hsa-miR-148a hsa-mir-148a 7 19664672
hsa-miR-148a hsa-mir-148a 7 17847008
hsa-miR-148a* hsa-mir-148a 7 19664672
hsa-miR-148a* hsa-mir-148a 7 17847008
hsa-miR-148b hsa-mir-148b 12 19664672
hsa-miR-148b hsa-mir-148b 12 17847008
hsa-miR-148b* hsa-mir-148b 12 19664672
hsa-miR-148b* hsa-mir-148b 12 17847008
hsa-miR-152 hsa-mir-152 17 19664672
hsa-miR-152 hsa-mir-152 17 17847008
hsa-miR-19a* hsa-mir-19a 13 19664672
hsa-miR-218 hsa-mir-218-1 4 19664672
hsa-miR-218 hsa-mir-218-2 5 19664672
hsa-miR-218-2* hsa-mir-218-2 5 19664672
hsa-miR-331-5p hsa-mir-331 12 19664672
hsa-miR-433 hsa-mir-433 14 19664672
hsa-miR-508-5p hsa-mir-508 X 19664672
hsa-miR-513a-5p hsa-mir-513a-1 X 19664672
hsa-miR-513a-5p hsa-mir-513a-2 X 19664672
hsa-miR-513b hsa-mir-513b X 19664672
hsa-miR-518c* hsa-mir-518c 19 19664672
hsa-miR-589* hsa-mir-589 7 19664672
hsa-miR-616 hsa-mir-616 12 19664672
hsa-miR-616* hsa-mir-616 12 19664672
hsa-miR-661 hsa-mir-661 8 19664672
hsa-miR-92a-1* hsa-mir-92a-1 13 19664672
hsa-miR-92a-2* hsa-mir-92a-2 X 19664672
hsa-miR-93 hsa-mir-93 7 19664672
hsa-miR-93* hsa-mir-93 7 19664672
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018