AutismKB 2.0

Annotation Detail for HLX


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Basic Information Top
Gene Symbol:HLX ( HB24,HLX1 )
Gene Full Name: H2.0-like homeobox
Band: 1q41
Quick LinksEntrez ID:3142; OMIM: 142995; Uniprot ID:HLX_HUMAN; ENSEMBL ID: ENSG00000136630; HGNC ID: 4978
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
400Phosphoserine.
404Phosphothreonine.
477Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021958
  • Location:chr1 219119381-219125017
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 219114140 219114658 518 4983
CTCF G2GSE9613 219118920 219119702 782 71
H3K27me3 colorectalcancer 219116188 219116991 803 2792
H3K27me3 colorectalcancer 219117551 219118652 1101 1280
H3K4me3 colorectalcancer 219118021 219118617 596 1063
hScc1 BcellGSE12603 219114174 219114658 484 4966
hScc1 CdLSGSE12603 219113879 219114796 917 5044
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 219127465 219127677 212 2554
hScc1 BcellGSE12603 219131357 219131781 424 6552
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 219119940 219120272 332 0
CTCF G2GSE9613 219122153 219122571 418 0
CTCF G2GSE9613 219124156 219124812 656 0
H3K27me3 colorectalcancer 219120340 219122005 1665 0
H3K4me3 colorectalcancer 219120272 219121193 921 0
TAF k562GSE8489 219120377 219120752 375 0
hScc1 BcellGSE12603 219119315 219119732 417 0
hScc1 BcellGSE12603 219120068 219120303 235 0
hScc1 BcellGSE12603 219124156 219124610 454 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018