Annotation Detail for HMGN2

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Basic Information Top

Gene Symbol:	HMGN2 ( HMG17,MGC5629,MGC88718 )
Gene Full Name:	high-mobility group nucleosomal binding domain 2
Band:	1p36.11
Quick Links	Entrez ID:3151; OMIM: 163910; Uniprot ID:HMGN2_HUMAN; ENSEMBL ID: ENSG00000198830; HGNC ID: 4986
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:3 results
Experimental PTM Sites from dbPTM:1 results
Predicted PTM Sites by profile HMM from dbPTM:2 results

Location(AA)	Modification
25	Phosphoserine.
29	Phosphoserine.
82	N6-acetyllysine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_005517
Location:chr1 26671500-26675047
strand:+

Upstream the gene:5 results
Downstream the gene:7 results
Inside the gene:11 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	26671139	26671774	635	44
Fos	K562	GSE19551	26670938	26671871	933	96
NRSF-mono	Jurkat	QuESTdata	26670323	26671712	1389	483
Rb	Quiescent	GSE19898	26670717	26671365	648	460
p130	Senescent	GSE19898	26670774	26671738	964	245

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	26689459	26689648	189	14506
Oct1	H2O2-Hela	GSE14283	26689693	26689722	29	14660
Oct1	Hela	GSE14283	26687350	26687431	81	12343
Oct1	Hela	GSE14283	26689693	26689721	28	14660
SRF	Hela	GSE8489	26683918	26684349	431	9086
SRF	k562	GSE8489	26683918	26684527	609	9175
TAF	k562	GSE8489	26683918	26684527	609	9175

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	26672487	26673203	716	0
PHF8	HeLa	GSE20725	26670846	26672717	1871	0
Rb	Growing	GSE19898	26671854	26672341	487	0
Rb	Quiescent	GSE19898	26671874	26672402	528	0
Rb	Senescent	GSE19898	26671819	26672429	610	0
Rb	shRbSenescence	GSE19898	26671842	26672262	420	0
hScc1	Bcell	GSE12603	26671179	26672387	1208	0
p130	Quiescent	GSE19898	26671914	26672376	462	0
p130	Senescent	GSE19898	26671829	26672297	468	0
p130	shRbQuiescent	GSE19898	26671875	26672332	457	0
p130	shRbSenescent	GSE19898	26670777	26672359	1582	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
436	mRNA	HMGN2	chr1	26483055	26486603	629	EST		chr1	26485838	26486467	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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