Annotation Detail for HMGCS1
Basic Information Top
| Gene Symbol: | HMGCS1 ( HMGCS,MGC90332 ) |
|---|---|
| Gene Full Name: | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| Band: | 5p12 |
| Quick Links | Entrez ID:3157; OMIM: 142940; Uniprot ID:HMCS1_HUMAN; ENSEMBL ID: ENSG00000112972; HGNC ID: 5007 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 4 | Phosphoserine. | |
| 46 | N6-acetyllysine. | |
| 246 | N6-acetyllysine. | |
| 273 | N6-acetyllysine. | |
| 321 | N6-acetyllysine. | |
| 476 | Phosphothreonine. | |
| 495 | Phosphoserine. | |
| 516 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 495 | Phosphoserine. | Swiss-Prot 53.0 |
| 495 | Phosphoserine | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 115 | Phosphoserine(CK2) | HMM predict |
| 202 | Sulfotyrosine | HMM predict |
| 205 | Sulfotyrosine | HMM predict |
| 205 | Phosphotyrosine(Syk) | HMM predict |
| 295 | Phosphotyrosine(INSR) | HMM predict |
| 310 | Phosphotyrosine(Syk) | HMM predict |
| 328 | Phosphoserine(ATM) | HMM predict |
| 393 | Phosphothreonine(MAPK) | HMM predict |
| 465 | Phosphothreonine(PKA) | HMM predict |
| 471 | Phosphothreonine(PKA) | HMM predict |
| 495 | Phosphoserine(CDC2) | HMM predict |
| 495 | Phosphoserine(CDK) | HMM predict |
- RefSeq ID: NM_002130
- Location:chr5 43325254-43349240
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | T30-glioblastoma | GSE21026 | 43348316 | 43350490 | 2174 | 163 |
| Oct1 | Hela | GSE14283 | 43351792 | 43351824 | 32 | 2568 |
| P300 | T30-glioblastoma | GSE21026 | 43348386 | 43350798 | 2412 | 352 |
| PHF8 | HeLa | GSE20725 | 43348656 | 43349949 | 1293 | 62 |
| Rb | Growing | GSE19898 | 43349357 | 43349594 | 237 | 235 |
| TAF | Hela | GSE8489 | 43350812 | 43351043 | 231 | 1687 |
| p130 | Quiescent | GSE19898 | 43349407 | 43349661 | 254 | 294 |
| p130 | Senescent | GSE19898 | 43349168 | 43349714 | 546 | 201 |
| p130 | shRbQuiescent | GSE19898 | 43348980 | 43349538 | 558 | 19 |
| p130 | shRbSenescent | GSE19898 | 43349000 | 43349707 | 707 | 113 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | Jurkat | GSE17954 | 43347573 | 43350827 | 3254 | 0 |
| CTCF | CD4 | GSE12889 | 43341786 | 43342146 | 360 | 0 |
| CTCF | CD4 | SISSRdata | 43341786 | 43342146 | 360 | 0 |
| CTCF | G2 | GSE9613 | 43341955 | 43342278 | 323 | 0 |
| CTCF | G2 | GSE9613 | 43348625 | 43349561 | 936 | 0 |
| H3K4me2 | HCT116 | GSE10453 | 43348456 | 43348917 | 461 | 0 |
| H3K4me3 | colorectal | cancer | 43347841 | 43348881 | 1040 | 0 |
| H3ac | HepG2 | E | 43347216 | 43349076 | 1860 | 0 |
| Oct1 | Hela | GSE14283 | 43332313 | 43332382 | 69 | 0 |
| PHF8 | 293T | GSE20725 | 43348717 | 43349472 | 755 | 0 |
| RARA | MCF7 | GSE15244 | 43330105 | 43330568 | 463 | 0 |
| TAF | Hela | GSE8489 | 43347813 | 43348816 | 1003 | 0 |
| hScc1 | Bcell | GSE12603 | 43348660 | 43349198 | 538 | 0 |
| p130 | Quiescent | GSE19898 | 43348911 | 43349354 | 443 | 0 |
Validated miRNA targets