AutismKB 2.0

Annotation Detail for HNRNPU


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Basic Information Top
Gene Symbol:HNRNPU ( HNRPU,SAF-A,U21.1,hnRNP U )
Gene Full Name: heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
Band: 1q44
Quick LinksEntrez ID:3192; OMIM: 602869; Uniprot ID:HNRPU_HUMAN; ENSEMBL ID: ENSG00000153187; HGNC ID: 5048
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine; partial.
4Phosphoserine.
26Phosphoserine.
50Omega-N-methylarginine.
59Phosphoserine.
66Phosphoserine.
188Phosphoserine.
234N6-acetyllysine.
265N6-acetyllysine.
271Phosphoserine.
286Phosphothreonine.
352N6-acetyllysine.
464N6-acetyllysine.
473Phosphotyrosine.
516N6-acetyllysine.
524N6-acetyllysine.
551N6-acetyllysine.
565N6-acetyllysine.
626N6-acetyllysine.
635N6-acetyllysine.
670N6-acetyllysine.
733Omega-N-methylated arginine.
739Dimethylated arginine; in A2780 ovarian
739Omega-N-methylated arginine.
814N6-acetyllysine.
Location(AA) Modifications Resource
2N-acetylserine.Swiss-Prot 53.0
3PhosphoserinePhospho.ELM 6.0
4Phosphoserine.Swiss-Prot 53.0
50Omega-N-methylarginine.Swiss-Prot 53.0
58PhosphoserinePhospho.ELM 6.0
59Phosphoserine.Swiss-Prot 53.0
269PhosphoserinePhospho.ELM 6.0
270Phosphoserine.Swiss-Prot 53.0
471PhosphotyrosinePhospho.ELM 6.0
472Phosphotyrosine.Swiss-Prot 53.0
732Omega-N-methylated arginine.Swiss-Prot 53.0
738Omega-N-methylated arginine.Swiss-Prot 53.0
Location(AA) Modification Resource
26Phosphoserine(PKA)HMM predict
26Phosphoserine(PKG)HMM predict
26Phosphoserine(PKA)HMM predict
128Phosphoserine(CK2)HMM predict
128Phosphoserine(CK1)HMM predict
168O-linkedHMM predict
192O-linkedHMM predict
197O-linkedHMM predict
265Phosphotyrosine(SRC)HMM predict
270Phosphoserine(CDK)HMM predict
270Phosphoserine(PKG)HMM predict
270Phosphoserine(IKK)HMM predict
270Phosphoserine(CDC2)HMM predict
325Phosphoserine(PKG)HMM predict
612Phosphotyrosine(Syk)HMM predict
638N-linkedHMM predict
692N-linkedHMM predict
697N-linkedHMM predict
714MethylarginineHMM predict
719MethylarginineHMM predict
726MethylarginineHMM predict
738MethylarginineHMM predict
772MethylarginineHMM predict
811GlycineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004501
  • Location:chr1 243080224-243094449
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 243111763 243111947 184 17406
H3ac HepG2E 243094682 243095371 689 577
SRF GMOGSE8489 243109291 243109469 178 14931
TAF HelaGSE8489 243094550 243095528 978 590
TAF k562GSE8489 243094598 243096954 2356 1327
hScc1 G2GSE9613 243094241 243094756 515 49
p130 SenescentGSE19898 243094393 243095096 703 295
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 243092805 243094756 1951 0
GABP k562GSE8489 243091435 243093092 1657 0
H3K4me3 colorectalcancer 243091992 243093056 1064 0
H3ac HepG2E 243090826 243091569 743 0
H3ac HepG2E 243091953 243092769 816 0
NFkBII GM15510GSE19485 243092408 243095360 2952 0
PHF8 Hs68plusFBSGSE20725 243092598 243095479 2881 0
TAF HelaGSE8489 243092041 243093507 1466 0
TAF k562GSE8489 243091253 243092737 1484 0
hScc1 BcellGSE12603 243092769 243094756 1987 0
hScc1 CdLSGSE12603 243092676 243094981 2305 0
hScc1 G2GSE9613 243092805 243093680 875 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 19586368
hsa-miR-1 hsa-mir-1-1 20 19586368
hsa-miR-1 hsa-mir-1-2 18 19586368
hsa-miR-1 hsa-mir-1-1 20 19586368
hsa-miR-133a hsa-mir-133a-1 18 19586368
hsa-miR-133a hsa-mir-133a-2 20 19586368
hsa-miR-133a hsa-mir-133a-1 18 19586368
hsa-miR-133a hsa-mir-133a-2 20 19586368
hsa-miR-133b hsa-mir-133b 6 19586368
hsa-miR-133b hsa-mir-133b 6 19586368
hsa-miR-206 hsa-mir-206 6 19586368
hsa-miR-206 hsa-mir-206 6 19586368
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2610 EST chr1 241342750 241343647 611 mRNA HNRPU chr1 241343003 241353868Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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